Prepares simulated training data and real bulk data for TAPE model training and prediction. The function performs variance filtering, gene intersection, log transformation, and per-sample scaling.
Arguments
- simudata
A list returned by [tape_simulate()] containing simulated pseudobulk expression and proportions.
- real_bulk
Numeric matrix with genes in rows and samples in columns.
- variance_threshold
Numeric scalar in `[0, 1]`. Fractional rank used to define the variance cutoff independently for simulated and real bulk data.
- scaler
Character scalar. Either `"mms"` for min-max scaling or `"ss"` for standard scaling.
Value
A named list with components:
- train_x
Numeric matrix of simulated training expression with samples in rows and genes in columns.
- train_y
Numeric matrix of simulated proportions with samples in rows and cell types in columns.
- test_x
Numeric matrix of processed real bulk expression with samples in rows and genes in columns.
- genename
Character vector of intersected gene names.
- celltypes
Character vector of cell-type names.
- samplename
Character vector of real bulk sample names.
Details
The current implementation applies scaling row-wise after `log1p` transformation, matching the intended sample-wise scaling direction.
Examples
## Build a tiny single-cell reference (genes x cells) ---------------------
set.seed(1)
n_genes <- 1000
cell_types <- c("Tcell", "Bcell", "Mono")
cells_per_type <- 100
n_cells <- length(cell_types) * cells_per_type
counts <- matrix(
rpois(n_genes * n_cells, lambda = 5),
nrow = n_genes, ncol = n_cells
)
rownames(counts) <- paste0("gene", seq_len(n_genes))
colnames(counts) <- paste0("cell", seq_len(n_cells))
meta <- data.frame(
cell_type = rep(cell_types, each = cells_per_type),
row.names = colnames(counts)
)
sc <- SeuratObject::CreateSeuratObject(counts = counts, meta.data = meta)
#> Warning: Data is of class matrix. Coercing to dgCMatrix.
## Simulate training pseudobulks (samples x genes) ------------------------
train_sim <- tape_simulate(
sc, celltype_col = "cell_type",
samplenum = 50, n = 100, sparse = FALSE, random_state = 1
)
#> [00:00:00] Simulation started
#> [00:00:00] Generating Dirichlet proportions
#> [00:00:00] Sampling cells and building pseudobulks
#>
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#> [00:00:00] Simulation finished
## Simulate a separate set to stand in for the real bulk ------------------
test_sim <- tape_simulate(
sc, celltype_col = "cell_type",
samplenum = 10, n = 100, sparse = FALSE, random_state = 2
)
#> [00:00:00] Simulation started
#> [00:00:00] Generating Dirichlet proportions
#> [00:00:00] Sampling cells and building pseudobulks
#>
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#> [00:00:00] Simulation finished
real_bulk <- t(test_sim$X) # tape_process expects genes x samples
## Variance filter, gene intersection, log1p, per-sample scaling ----------
processed <- tape_process(train_sim, real_bulk, scaler = "mms")
#> [00:00:00] Processing started
#> [00:00:00] Applying variance filtering
#> [00:00:00] Intersected gene number: 961
#> [00:00:00] Applying log1p transform
#> [00:00:00] Applying mms scaling
#> [00:00:00] Processing finished
head(processed$train_x)
#> gene1 gene2 gene3 gene4 gene5 gene6 gene7
#> sample_1 0.2862654 0.5974002 0.7550497 0.6182797 0.5283763 0.6338315 0.5816312
#> sample_2 0.7394278 0.5810004 0.6412827 0.4571170 0.6874380 0.7005105 0.3212391
#> sample_3 0.6217365 0.6101717 0.5751990 0.4615934 0.5039661 0.7126355 0.5927379
#> sample_4 0.5866482 0.7347215 0.8437349 0.7458074 0.2594087 0.7012096 0.5216740
#> sample_5 0.3551053 0.6051188 0.7357647 0.5939592 0.3060971 0.2055049 0.4211577
#> sample_6 0.3891228 0.6591914 0.5061833 0.5777905 0.2802925 0.6012782 0.6012782
#> gene8 gene10 gene11 gene12 gene13 gene14 gene15
#> sample_1 0.5868980 0.5067694 0.5551382 0.4464206 0.4016462 0.62865779 0.6389952
#> sample_2 0.6346374 0.3719360 0.5742356 0.2549216 0.5058340 0.59448954 0.2771720
#> sample_3 0.4309448 0.6275017 0.7735204 0.6788804 0.3937349 0.09144864 0.6159599
#> sample_4 0.7458074 0.3872312 0.6559217 0.4183332 0.4491082 0.60992202 0.2528686
#> sample_5 0.5317963 0.1797979 0.4506878 0.2562403 0.4624156 0.64384005 0.7304379
#> sample_6 0.4079179 0.5777905 0.7439821 0.5541142 0.1942708 0.58368000 0.5718892
#> gene16 gene17 gene18 gene19 gene20 gene21 gene22
#> sample_1 0.5551382 0.4795092 0.5067694 0.3214130 0.5974002 0.6492922 0.5337505
#> sample_2 0.8473246 0.5058340 0.7070279 0.7587200 0.5470406 0.4360218 0.7265050
#> sample_3 0.7570414 0.4061912 0.5099693 0.4371004 0.4798288 0.2921165 0.7680377
#> sample_4 0.4183332 0.2265613 0.5983082 0.5216740 0.4734972 0.5749415 0.6272567
#> sample_5 0.3245731 0.3368248 0.5827562 0.2875018 0.4389121 0.5545566 0.3793000
#> sample_6 0.8101012 0.4819223 0.4635947 0.7384046 0.8960144 0.3575289 0.4574601
#> gene23 gene24 gene25 gene26 gene27 gene28 gene29
#> sample_1 0.8567274 0.5710660 0.4185258 0.7001824 0.5710660 0.2862654 0.28626538
#> sample_2 0.5058340 0.6146230 0.3066137 0.7005105 0.8096347 0.6743149 0.12599659
#> sample_3 0.4493727 0.4676846 0.5985608 0.7070368 0.7293672 0.6447289 0.23335633
#> sample_4 0.7678540 0.6041209 0.4429790 0.4795629 0.5276407 0.4795629 0.29189146
#> sample_5 0.5317963 0.4092604 0.3793000 0.2625198 0.3245731 0.1408019 0.43891212
#> sample_6 0.5481653 0.7772270 0.4574601 0.4203817 0.3954012 0.2997922 0.03564357
#> gene30 gene31 gene32 gene33 gene34 gene35 gene36
#> sample_1 0.7102436 0.5013398 0.60786060 0.5710660 0.6026356 0.5175950 0.6595491
#> sample_2 0.8784154 0.8159456 0.08712398 0.5058340 0.7523014 0.6012140 0.6079251
#> sample_3 0.6732162 0.6101717 0.21350280 0.4979505 0.6043721 0.6275017 0.9540346
#> sample_4 0.6559217 0.6157117 0.52167399 0.4491082 0.8437349 0.4368370 0.7068216
#> sample_5 0.5658696 0.4330062 0.36722808 0.4448060 0.5771384 0.2687857 0.5375033
#> sample_6 0.5895577 0.7661870 0.63616246 0.5001367 0.3702071 0.3954012 0.6187719
#> gene37 gene38 gene39 gene40 gene41 gene42 gene43
#> sample_1 0.5763539 0.6026356 0.5868980 0.6286578 0.3618348 0.3503488 0.5067694
#> sample_2 0.4711078 0.5264999 0.3139343 0.2992772 0.7394278 0.2099771 0.4430682
#> sample_3 0.4554895 0.6504488 0.4185943 0.6101717 0.7680377 0.6504488 0.3749499
#> sample_4 0.5037005 0.5454682 0.5983082 0.3621094 0.3746973 0.2463139 0.4856160
#> sample_5 0.5088547 0.4799182 0.4211577 0.4857288 0.1211040 0.5883632 0.3913216
#> sample_6 0.4880063 0.5954238 0.3954012 0.4635947 0.5895577 0.2737638 0.6419366
#> gene44 gene45 gene46 gene47 gene48 gene49 gene50
#> sample_1 0.3789705 0.3675591 0.1840576 0.5337505 0.5921543 0.48498387 0.7893799
#> sample_2 0.7779028 0.3791168 0.5944895 0.8159456 0.7587200 0.29192487 0.7394278
#> sample_3 0.8704804 0.3178559 0.6159599 0.8810568 0.6732162 0.48588193 0.7625447
#> sample_4 0.6444894 0.5924840 0.2594087 0.7842806 0.5631877 0.43683699 0.6899532
#> sample_5 0.6438400 0.4092604 0.2750379 0.8196806 0.4389121 0.08129934 0.7090314
#> sample_6 0.3320076 0.2540907 0.3638748 0.7827316 0.3891228 0.56597612 0.6476994
#> gene51 gene52 gene53 gene54 gene55 gene56 gene57
#> sample_1 0.3903327 0.3675591 0.3038978 0.7102436 0.7649040 0.4958991 0.19018076
#> sample_2 0.5538598 0.5058340 0.6146230 0.8033121 0.8784154 0.5877517 0.09493429
#> sample_3 0.3497131 0.4247761 0.5219386 0.3874867 0.5219386 0.6275017 0.32425531
#> sample_4 0.4245141 0.3240177 0.4552245 0.6330122 0.9591383 0.6955868 0.13939164
#> sample_5 0.4799182 0.2750379 0.4915277 0.4092604 0.5602187 0.5317963 0.10789686
#> sample_6 0.3384087 0.7216086 0.5718892 0.6361625 0.4389792 0.3191637 0.35116926
#> gene58 gene59 gene60 gene61 gene62 gene63 gene64
#> sample_1 0.5974002 0.3789705 0.2205851 0.5391137 0.4016462 0.5868980 0.4574963
#> sample_2 0.5402075 0.4147944 0.5402075 0.5606654 0.8285321 0.2697715 0.3503016
#> sample_3 0.5575537 0.3999697 0.5634473 0.5338588 0.7515276 0.5398006 0.5927379
#> sample_4 0.8650586 0.4856160 0.6272567 0.6099220 0.6387565 0.3176206 0.5335953
#> sample_5 0.5602187 0.3793000 0.3122689 0.3429312 0.3913216 0.3551053 0.2812766
#> sample_6 0.6706387 0.5061833 0.6012782 0.4940778 0.7882259 0.3127206 0.6245802
#> gene65 gene66 gene68 gene69 gene70 gene71 gene72
#> sample_1 0.6492922 0.3846577 0.6441487 0.4740232 0.6850182 0.2921560 0.4904471
#> sample_2 0.8285321 0.6874380 0.5810004 0.5742356 0.6079251 0.4571170 0.5538598
#> sample_3 0.7460033 0.4061912 0.7570414 0.2921165 0.8224044 0.5219386 0.6217365
#> sample_4 0.7235934 0.4491082 0.3684101 0.7842806 0.2854237 0.5335953 0.4734972
#> sample_5 0.4740958 0.4092604 0.4092604 0.6217774 0.7251011 0.2937136 0.5658696
#> sample_6 0.7103579 0.4880063 0.6129522 0.3127206 0.5122174 0.4635947 0.6129522
#> gene73 gene74 gene75 gene76 gene77 gene78 gene79
#> sample_1 0.5229911 0.8897667 0.6286578 0.4574963 0.5974002 0.4241284 0.6389952
#> sample_2 0.5470406 0.7651263 0.6346374 0.7969776 0.6279791 0.1414215 0.4430682
#> sample_3 0.7126355 0.7570414 0.8277856 0.6958069 0.5219386 0.5159601 0.5869034
#> sample_4 0.4674190 0.5216740 0.7733398 0.3934781 0.8544162 0.2331603 0.7842806
#> sample_5 0.4973149 0.6657349 0.4799182 0.6051188 0.4857288 0.3732704 0.6217774
#> sample_6 0.6071210 0.4819223 0.6187719 0.6245802 0.6649206 0.3127206 0.4940778
#> gene80 gene81 gene82 gene83 gene84 gene85 gene86
#> sample_1 0.8136305 0.6951373 0.7001824 0.2980334 0.6338315 0.4630168 0.6130753
#> sample_2 0.5127366 0.6611407 0.6743149 0.7715206 0.7005105 0.4919862 0.4005685
#> sample_3 0.3306407 0.5810571 0.4979505 0.6845335 0.4493727 0.6389978 0.6845335
#> sample_4 0.5808007 0.4795629 0.4306821 0.4674190 0.4734972 0.4245141 0.7124229
#> sample_5 0.3490247 0.6162352 0.4211577 0.2562403 0.4152152 0.4565577 0.4565577
#> sample_6 0.4880063 0.7495490 0.3255926 0.5659761 0.5302461 0.5659761 0.5600511
#> gene87 gene88 gene89 gene91 gene92 gene93 gene94
#> sample_1 0.4574963 0.5175950 0.4958991 0.6389952 0.5657674 0.4795092 0.6182797
#> sample_2 0.4711078 0.6146230 0.4641197 0.6213076 0.8285321 0.3934330 0.6412827
#> sample_3 0.5869034 0.7515276 0.6958069 0.3560429 0.6389978 0.4061912 0.2068547
#> sample_4 0.2724451 0.5097039 0.5631877 0.7402697 0.6673096 0.5216740 0.1461900
#> sample_5 0.3490247 0.4915277 0.2937136 0.2562403 0.4032932 0.5431990 0.3913216
#> sample_6 0.6187719 0.6990641 0.4016662 0.1263488 0.5659761 0.4574601 0.1875486
#> gene95 gene96 gene97 gene98 gene99 gene100 gene101
#> sample_1 0.7451584 0.6182797 0.6078606 0.4464206 0.5974002 0.6799440 0.5816312
#> sample_2 0.4919862 0.5127366 0.6677342 0.4641197 0.3503016 0.3719360 0.8784154
#> sample_3 0.3497131 0.5869034 0.4554895 0.6732162 0.6159599 0.4676846 0.6845335
#> sample_4 0.4856160 0.4491082 0.4976847 0.6330122 0.6955868 0.4734972 0.7180135
#> sample_5 0.4506878 0.7304379 0.7036548 0.1145080 0.4448060 0.3973136 0.4152152
#> sample_6 0.5061833 0.5954238 0.5541142 0.7272179 0.4635947 0.5242488 0.5242488
#> gene102 gene103 gene104 gene105 gene106 gene107 gene108
#> sample_1 0.3789705 0.41852581 0.6900826 0.4904471 0.3618348 0.5444660 0.3330255
#> sample_2 0.1337178 0.11825769 0.4919862 0.7329726 0.2697715 0.4571170 0.3791168
#> sample_3 0.4979505 0.08451531 0.7404685 0.4185943 0.5516480 0.1190179 0.4185943
#> sample_4 0.4491082 0.16649065 0.5156951 0.5037005 0.5866482 0.7568514 0.2594087
#> sample_5 0.3611731 0.38531711 0.5030906 0.3490247 0.3672281 0.2246356 0.5375033
#> sample_6 0.4635947 0.35116926 0.7772270 0.5600511 0.2540907 0.2009778 0.2606630
#> gene109 gene110 gene111 gene112 gene113 gene114 gene115
#> sample_1 0.5763539 0.2446586 0.4016462 0.6544256 0.5013398 0.6026356 0.3903327
#> sample_2 0.6079251 0.4147944 0.6346374 0.8033121 0.6611407 0.4711078 0.5333607
#> sample_3 0.7349232 0.6159599 0.7844547 1.0000000 0.4309448 0.7182234 0.4615934
#> sample_4 0.7068216 0.4976847 0.6502111 0.6387565 0.5037005 0.8060403 0.2724451
#> sample_5 0.3184276 0.2562403 0.5939592 0.4857288 0.3429312 0.4389121 0.2625198
#> sample_6 0.6990641 0.3765259 0.5481653 0.8209783 0.6877268 0.5182393 0.4819223
#> gene116 gene117 gene118 gene119 gene120 gene121 gene122
#> sample_1 0.4904471 0.3903327 0.24465864 0.4016462 0.7202665 0.6850182 0.2625706
#> sample_2 0.9518888 0.5264999 0.08712398 0.4147944 0.7651263 0.6412827 0.2992772
#> sample_3 0.2333563 0.7238007 0.71263547 0.5219386 0.3560429 0.5516480 0.2661473
#> sample_4 0.6387565 0.4613281 0.47349724 0.4429790 0.8006156 0.5513866 0.1799466
#> sample_5 0.3611731 0.3429312 0.71439793 0.5658696 0.4211577 0.5715095 0.3551053
#> sample_6 0.3575289 0.6706387 0.37020714 0.1332119 0.5001367 0.7882259 0.4513126
#> gene123 gene124 gene125 gene126 gene127 gene128 gene129
#> sample_1 0.5121877 0.3903327 0.4408652 0.3959955 0.4904471 0.7501087 0.5229911
#> sample_2 0.5810004 0.5742356 0.4850410 0.5470406 0.2845565 0.7070279 0.4005685
#> sample_3 0.8492113 0.6217365 0.3749499 0.7844547 0.4123994 0.6958069 0.6389978
#> sample_4 0.7068216 0.7951807 0.4734972 0.3240177 0.4613281 0.6387565 0.6444894
#> sample_5 0.6602768 0.2687857 0.2937136 0.4799182 0.3245731 0.5203484 0.4973149
#> sample_6 0.4141564 0.4451524 0.2933066 0.3954012 0.6012782 0.4819223 0.2672207
#> gene130 gene131 gene132 gene133 gene134 gene135 gene136
#> sample_1 0.5604582 0.4352981 0.5710660 0.4408652 0.5175950 0.5604582 0.4072847
#> sample_2 0.8597952 0.7135327 0.6213076 0.7200251 0.4711078 0.6743149 0.7394278
#> sample_3 0.6561574 0.8438696 0.7126355 0.8277856 0.6101717 0.6845335 0.7680377
#> sample_4 0.6955868 0.4183332 0.5690705 0.6272567 0.6387565 0.3997117 0.5395378
#> sample_5 0.2687857 0.3732704 0.5488834 0.6106824 0.4973149 0.3793000 0.5030906
#> sample_6 0.4203817 0.4141564 0.4141564 0.6877268 0.4880063 0.3702071 0.5242488
#> gene137 gene138 gene140 gene141 gene142 gene143 gene144
#> sample_1 0.5444660 0.3214130 0.2506428 0.09680512 0.6441487 0.7302515 0.6595491
#> sample_2 0.7523014 0.1796792 0.5264999 0.52649995 0.4005685 0.6545343 0.6939806
#> sample_3 0.7899065 0.6732162 0.3999697 0.27916091 0.5159601 0.3874867 0.5398006
#> sample_4 0.5037005 0.5395378 0.2659341 0.36841010 0.4856160 0.4613281 0.7788153
#> sample_5 0.4682616 0.1276850 0.4448060 0.24363999 0.2246356 0.4032932 0.4032932
#> sample_6 0.4079179 0.6591914 0.4819223 0.26722070 0.5541142 0.5718892 0.4265939
#> gene145 gene146 gene148 gene149 gene150 gene151 gene152
#> sample_1 0.5657674 0.8087982 0.5816312 0.4630168 0.4352981 0.6544256 0.5121877
#> sample_2 0.6479150 0.4500999 0.6346374 0.5877517 0.5402075 0.5058340 0.4500999
#> sample_3 0.4919225 0.5810571 0.6101717 0.4979505 0.2856459 0.4247761 0.5751990
#> sample_4 0.5749415 0.5037005 0.5395378 0.6843087 0.5808007 0.3621094 0.2789416
#> sample_5 0.7727792 0.6493294 0.5030906 0.5715095 0.5030906 0.4448060 0.3184276
#> sample_6 0.4451524 0.5242488 0.6934009 0.8747697 0.4697166 0.1875486 0.3954012
#> gene153 gene155 gene156 gene157 gene158 gene159 gene160
#> sample_1 0.5283763 0.5710660 0.3330255 0.7451584 0.3675591 0.4958991 0.5974002
#> sample_2 0.5606654 0.7842731 0.6545343 0.6012140 0.2474721 0.5058340 0.5742356
#> sample_3 0.5159601 0.7070368 0.4798288 0.2856459 0.5099693 0.3050147 0.3306407
#> sample_4 0.3112095 0.4121392 0.3746973 0.6843087 0.1529725 0.5276407 0.4976847
#> sample_5 0.2937136 0.5545566 0.2937136 0.5883632 0.3973136 0.4032932 0.1990996
#> sample_6 0.3384087 0.5600511 0.2276538 0.6012782 0.5182393 0.3255926 0.6649206
#> gene161 gene162 gene163 gene164 gene165 gene167 gene168
#> sample_1 0.3272256 0.5067694 0.7893799 0.5121877 0.3789705 0.4241284 0.7052178
#> sample_2 0.3212391 0.5264999 0.6346374 0.6079251 0.4641197 0.5877517 0.5058340
#> sample_3 0.2333563 0.6618548 0.8224044 0.3433695 0.3686612 0.6732162 0.7404685
#> sample_4 0.4734972 0.6157117 0.8276395 0.5454682 0.6616212 0.7235934 0.7291628
#> sample_5 0.2750379 0.2562403 1.0000000 0.3973136 0.2625198 0.3122689 0.4624156
#> sample_6 0.2276538 0.2276538 0.8426128 0.3384087 0.8155448 0.5600511 0.7047164
#> gene169 gene170 gene171 gene172 gene173 gene174 gene175
#> sample_1 0.5498075 0.5391137 0.4904471 0.5283763 0.5974002 0.7698174 0.4297192
#> sample_2 1.0000000 0.2992772 0.4218850 0.5606654 0.3503016 0.6808828 0.4218850
#> sample_3 0.5159601 0.7182234 0.3497131 0.3623589 0.2530753 0.6332554 0.5985608
#> sample_4 0.6729869 0.3112095 0.6559217 0.4491082 0.5572931 0.4674190 0.6099220
#> sample_5 0.5375033 0.2436400 0.2937136 0.5030906 0.2309843 0.2182728 0.2687857
#> sample_6 0.3828311 0.5302461 0.5659761 0.2143460 0.5242488 0.4079179 0.6071210
#> gene176 gene177 gene178 gene179 gene180 gene181 gene182
#> sample_1 0.6595491 0.7302515 0.7052178 0.6338315 0.4241284 0.6130753 0.6026356
#> sample_2 0.5470406 0.6743149 0.5538598 0.3862825 0.4005685 0.5538598 0.6939806
#> sample_3 0.5869034 0.5159601 0.6101717 0.1598878 0.5810571 0.9847588 0.5219386
#> sample_4 0.4245141 0.6330122 0.8276395 0.7897357 0.5037005 0.5454682 0.7291628
#> sample_5 0.6602768 0.3853171 0.7463889 0.3611731 0.5375033 0.5203484 0.6217774
#> sample_6 0.5061833 0.7328166 1.0000000 0.3954012 0.5954238 0.5362313 0.6476994
#> gene183 gene184 gene185 gene186 gene187 gene188 gene189
#> sample_1 0.5229911 0.5067694 0.5763539 0.3675591 0.5444660 0.5710660 0.3097491
#> sample_2 0.5196253 0.6079251 0.6012140 0.5402075 0.2325239 0.7070279 0.4711078
#> sample_3 0.7404685 0.7014272 0.5159601 0.4919225 0.2465171 0.5634473 0.7404685
#> sample_4 0.2659341 0.1257475 0.6843087 0.3934781 0.4734972 0.4856160 0.4121392
#> sample_5 0.4092604 0.2436400 0.4211577 0.2562403 0.3490247 0.2373191 0.4799182
#> sample_6 0.6361625 0.6245802 0.5954238 0.6303770 0.2672207 0.6649206 0.7103579
#> gene190 gene191 gene192 gene193 gene194 gene195 gene196
#> sample_1 0.4129113 0.6748601 0.2446586 0.4129113 0.3846577 0.7352298 0.9131152
#> sample_2 0.2771720 0.3575285 0.6479150 0.4641197 0.6012140 0.5877517 0.8348078
#> sample_3 0.3937349 0.5693291 0.6101717 0.4493727 0.3999697 0.6788804 0.7014272
#> sample_4 0.3431255 0.1799466 0.5572931 0.5690705 0.2918915 0.8597422 0.7842806
#> sample_5 0.4448060 0.1862462 0.2687857 0.1538593 0.1990996 0.5260780 0.7727792
#> sample_6 0.4880063 0.6534510 0.6763458 0.5541142 0.5836800 0.8209783 0.6419366
#> gene197 gene198 gene200 gene201 gene202 gene203 gene204
#> sample_1 0.3038978 0.5444660 0.6595491 0.7550497 0.5391137 0.3214130 0.4016462
#> sample_2 0.5538598 0.5127366 0.5944895 0.7265050 0.7715206 0.5470406 0.3575285
#> sample_3 0.4432430 0.3686612 0.7789927 0.6561574 0.6447289 0.6561574 0.7460033
#> sample_4 0.4916566 0.5216740 0.4856160 0.7842806 0.6502111 0.6673096 0.5216740
#> sample_5 0.6217774 0.3793000 0.2812766 0.5431990 0.4092604 0.4211577 0.4740958
#> sample_6 0.6591914 0.4880063 0.4513126 0.7103579 0.4451524 0.7216086 0.5182393
#> gene205 gene206 gene207 gene208 gene209 gene210 gene211
#> sample_1 0.5175950 0.7401988 0.5551382 0.8136305 0.8519735 0.4519643 0.3732710
#> sample_2 0.5058340 0.5606654 0.6346374 0.5606654 0.6939806 0.7458707 0.5877517
#> sample_3 0.4432430 0.4185943 0.5751990 0.7460033 0.5279048 0.6732162 0.6043721
#> sample_4 0.7291628 0.6502111 0.6272567 0.5156951 0.8967557 0.4916566 0.5749415
#> sample_5 0.7780284 0.5317963 0.6383402 0.4448060 0.7036548 0.3611731 0.4330062
#> sample_6 0.5541142 0.6071210 0.8209783 0.5302461 0.6419366 0.3127206 0.4880063
#> gene212 gene213 gene214 gene215 gene216 gene217 gene218
#> sample_1 0.6130753 0.5283763 0.5013398 0.6646627 0.7550497 0.3214130 0.5444660
#> sample_2 0.6412827 0.4147944 0.4430682 0.6611407 0.6213076 0.3430593 0.6479150
#> sample_3 0.5869034 0.4979505 0.4676846 0.5634473 0.7735204 0.3497131 0.4309448
#> sample_4 0.6786533 0.3809709 0.5216740 0.5690705 0.7347215 0.4976847 0.3176206
#> sample_5 0.2055049 0.3368248 0.2937136 0.3184276 0.5545566 0.3429312 0.3611731
#> sample_6 0.6419366 0.3384087 0.5122174 0.5182393 0.5481653 0.3891228 0.5001367
#> gene219 gene221 gene222 gene223 gene224 gene225 gene226
#> sample_1 0.7942479 0.4574963 0.5710660 0.5551382 0.4241284 0.6646627 0.5391137
#> sample_2 0.5877517 0.3719360 0.4711078 0.7458707 0.2845565 0.6677342 0.6213076
#> sample_3 0.6447289 0.5751990 0.3937349 0.4123994 0.4615934 0.5634473 0.3623589
#> sample_4 0.7291628 0.4734972 0.8703654 0.4552245 0.6330122 0.6041209 0.3367701
#> sample_5 0.6493294 0.3672281 0.6217774 0.5827562 0.1408019 0.6051188 0.5088547
#> sample_6 0.5122174 0.4574601 0.5242488 0.5122174 0.4880063 0.4635947 0.4016662
#> gene227 gene228 gene229 gene230 gene231 gene232 gene233
#> sample_1 0.4464206 0.4129113 0.5337505 0.4630168 0.6900826 0.5444660 0.6078606
#> sample_2 0.2697715 0.7969776 0.5674573 0.4005685 0.6611407 0.7265050 0.7005105
#> sample_3 0.4432430 0.7735204 0.5575537 0.7238007 0.4615934 0.6043721 0.7070368
#> sample_4 0.4368370 0.4306821 0.3809709 0.4916566 0.7513346 0.3112095 0.6099220
#> sample_5 0.4448060 0.7989298 0.2750379 0.4506878 0.2937136 0.4799182 0.5771384
#> sample_6 0.5122174 0.5895577 0.4880063 0.5895577 0.5895577 0.6591914 0.5600511
#> gene234 gene235 gene236 gene237 gene238 gene239 gene240
#> sample_1 0.6697663 0.6130753 0.6389952 0.6748601 0.4072847 0.5444660 0.5391137
#> sample_2 0.3934330 0.2250250 0.4711078 0.5333607 0.6611407 0.4076889 0.4780816
#> sample_3 0.7515276 0.6618548 0.3999697 0.4432430 0.3686612 0.5159601 0.7953481
#> sample_4 0.7235934 0.4613281 0.5276407 0.4734972 0.5037005 0.4245141 0.5395378
#> sample_5 0.6982681 0.2182728 0.3429312 0.6548083 0.4915277 0.1990996 0.4330062
#> sample_6 0.6649206 0.2737638 0.7272179 0.5600511 0.4141564 0.4327931 0.6591914
#> gene241 gene242 gene243 gene244 gene245 gene246 gene247
#> sample_1 0.5498075 0.6850182 0.6130753 0.5710660 0.3155875 0.6900826 0.6234739
#> sample_2 0.6677342 0.6808828 0.2549216 0.3430593 0.4500999 0.7906313 0.8159456
#> sample_3 0.7570414 0.3874867 0.4919225 0.4615934 0.0000000 0.7070368 0.5634473
#> sample_4 0.6099220 0.5924840 0.5454682 0.5216740 0.3621094 0.6786533 0.5631877
#> sample_5 0.5883632 0.3973136 0.4973149 0.5431990 0.4506878 0.6711827 0.4857288
#> sample_6 0.7047164 0.4203817 0.5777905 0.5600511 0.4141564 0.4940778 0.6245802
#> gene248 gene249 gene250 gene251 gene252 gene253 gene254
#> sample_1 0.5391137 0.3214130 0.4241284 0.6026356 0.6748601 0.5337505 0.6748601
#> sample_2 0.3791168 0.4989172 0.6743149 0.2697715 0.7394278 0.5538598 0.3212391
#> sample_3 0.7349232 0.4676846 0.7735204 0.5338588 0.5219386 0.7953481 0.5985608
#> sample_4 0.7458074 0.6559217 0.5866482 0.4491082 0.4916566 0.5216740 0.3934781
#> sample_5 0.7197545 0.3732704 0.3060971 0.5088547 0.7675205 0.4506878 0.1862462
#> sample_6 0.5302461 0.4697166 0.4574601 0.3765259 0.5541142 0.7328166 0.3702071
#> gene255 gene256 gene257 gene258 gene259 gene260 gene261
#> sample_1 0.4574963 0.4016462 0.4958991 0.4519643 0.5816312 0.6338315 0.4352981
#> sample_2 0.7135327 0.5674573 0.3066137 0.5127366 0.6545343 0.5674573 0.5264999
#> sample_3 0.8863307 0.7126355 0.4979505 0.7182234 0.5219386 0.6217365 0.8385182
#> sample_4 0.6955868 0.4856160 0.3557951 0.3997117 0.4795629 0.5983082 0.8168598
#> sample_5 0.5827562 0.6162352 0.5260780 0.5030906 0.1733351 0.6438400 0.5715095
#> sample_6 0.6877268 0.5422043 0.4940778 0.4513126 0.5302461 0.4819223 0.5362313
#> gene262 gene263 gene264 gene265 gene266 gene267 gene268
#> sample_1 0.4297192 0.3732710 0.7152598 0.4795092 0.6544256 0.6441487 0.6799440
#> sample_2 0.5333607 0.5058340 0.6545343 0.5196253 0.8410720 0.7651263 0.5944895
#> sample_3 0.5099693 0.6675411 0.6901757 0.6675411 0.8224044 0.6217365 0.5039661
#> sample_4 0.6616212 0.4734972 0.4491082 0.5749415 0.6387565 0.6559217 0.8060403
#> sample_5 0.3245731 0.3245731 0.5088547 0.3184276 0.5317963 0.6106824 0.6273089
#> sample_6 0.4079179 0.5718892 0.5001367 0.6534510 0.6303770 0.4635947 0.6934009
#> gene269 gene270 gene271 gene272 gene273 gene274 gene275
#> sample_1 0.42412843 0.6286578 0.5067694 0.5868980 0.4685258 0.4408652 0.3618348
#> sample_2 0.29192487 0.6079251 0.8159456 0.4711078 0.7715206 0.4641197 0.4780816
#> sample_3 0.48588193 0.4493727 0.5927379 0.5338588 0.5927379 0.5219386 0.6447289
#> sample_4 0.70682164 0.9694073 0.5037005 0.5631877 0.5749415 0.4916566 0.5276407
#> sample_5 0.29371361 0.6548083 0.5375033 0.3122689 0.4032932 0.5883632 0.4032932
#> sample_6 0.08483138 0.5422043 0.4079179 0.3447959 0.6649206 0.5362313 0.7103579
#> gene276 gene277 gene278 gene279 gene280 gene281 gene282
#> sample_1 0.7001824 0.4685258 0.3214130 0.5498075 0.7451584 0.4297192 0.8567274
#> sample_2 0.8033121 0.3791168 0.5264999 0.5127366 0.5127366 0.6808828 0.8784154
#> sample_3 0.7844547 0.1327051 0.3306407 0.6958069 0.7460033 0.6043721 0.7404685
#> sample_4 0.8437349 0.4429790 0.5335953 0.4552245 0.7733398 0.7347215 0.5631877
#> sample_5 0.5375033 0.3551053 0.4799182 0.4565577 0.5545566 0.5375033 0.6273089
#> sample_6 0.6934009 0.4141564 0.3255926 0.3575289 0.5302461 0.7159886 0.4880063
#> gene283 gene284 gene285 gene286 gene287 gene288 gene289
#> sample_1 0.3789705 0.8232687 0.6900826 0.4685258 0.4849839 0.3903327 0.34458701
#> sample_2 0.6279791 0.6412827 0.4289608 0.5877517 0.7265050 0.4989172 0.44306818
#> sample_3 0.8007795 0.5039661 0.7014272 0.4371004 0.6732162 0.7238007 0.43710040
#> sample_4 0.4674190 0.7678540 0.4183332 0.4734972 0.8114551 0.6673096 0.38097094
#> sample_5 0.3672281 0.8300002 0.4211577 0.4032932 0.4330062 0.4565577 0.33682484
#> sample_6 0.2342853 0.5481653 0.5061833 0.5362313 0.3702071 0.6820418 0.09873559
#> gene290 gene291 gene292 gene293 gene294 gene295 gene296
#> sample_1 0.5498075 0.3503488 0.2566134 0.6389952 0.2326494 0.1901808 0.3038978
#> sample_2 0.2175094 0.4850410 0.2400063 0.8096347 0.5333607 0.4360218 0.5196253
#> sample_3 0.6447289 0.6101717 0.6159599 0.3306407 0.5575537 0.8116120 0.6675411
#> sample_4 0.4916566 0.4734972 0.3934781 0.4306821 0.3684101 0.2724451 0.7012096
#> sample_5 0.3307055 0.3913216 0.1603659 0.4799182 0.3184276 0.2875018 0.2937136
#> sample_6 0.4697166 0.4513126 0.4819223 0.5895577 0.1400590 0.2868067 0.4265939
#> gene297 gene298 gene299 gene300 gene301 gene302 gene303
#> sample_1 0.5604582 0.7302515 0.5816312 0.5121877 0.6492922 0.4958991 0.5921543
#> sample_2 0.4641197 0.5264999 0.6346374 0.5742356 0.3719360 0.6079251 0.9336694
#> sample_3 0.5159601 0.6275017 0.6043721 0.6101717 0.5516480 0.5398006 0.4309448
#> sample_4 0.5454682 0.7897357 0.5749415 0.5808007 0.4121392 0.5156951 0.4674190
#> sample_5 0.5088547 0.7036548 0.5602187 0.6383402 0.4799182 0.6766202 0.4624156
#> sample_6 0.2672207 0.5600511 0.6071210 0.2933066 0.4758258 0.4819223 0.2672207
#> gene304 gene305 gene306 gene308 gene309 gene310 gene311
#> sample_1 0.5121877 0.3388126 0.7942479 0.5868980 0.7401988 0.6234739 0.6078606
#> sample_2 0.5264999 0.4571170 0.4500999 0.6279791 0.7458707 0.5606654 0.5127366
#> sample_3 0.6275017 0.5338588 0.5693291 0.7126355 0.4185943 0.6275017 0.6732162
#> sample_4 0.8006156 0.6041209 0.6041209 0.6673096 0.8703654 0.6843087 0.4183332
#> sample_5 0.5030906 0.4565577 0.5260780 0.4389121 0.6162352 0.3307055 0.3732704
#> sample_6 0.2276538 0.7882259 0.8533708 0.4079179 0.4819223 0.6129522 0.6361625
#> gene312 gene313 gene314 gene315 gene316 gene317 gene319
#> sample_1 0.3789705 0.5067694 0.7698174 0.5710660 0.5763539 0.3388126 0.6182797
#> sample_2 0.4919862 0.5402075 0.7135327 0.4360218 0.6479150 0.1414215 0.4147944
#> sample_3 0.7182234 0.4858819 0.7014272 0.7953481 0.7349232 0.6845335 0.6561574
#> sample_4 0.6559217 0.4491082 0.8914967 0.7513346 0.5983082 0.2659341 0.5513866
#> sample_5 0.4682616 0.4092604 0.7036548 0.4506878 0.6383402 0.5260780 0.7090314
#> sample_6 0.3954012 0.7495490 0.5541142 0.3575289 0.7272179 0.4389792 0.5362313
#> gene320 gene321 gene322 gene324 gene325 gene326 gene327
#> sample_1 0.6492922 0.4795092 0.6286578 0.5013398 0.4072847 0.4904471 0.7302515
#> sample_2 0.5674573 0.5196253 0.8033121 0.5402075 0.6808828 0.1414215 0.5402075
#> sample_3 0.6332554 0.4493727 0.8062008 0.7515276 0.4858819 0.3050147 0.6732162
#> sample_4 0.5037005 0.5395378 0.5924840 0.4856160 0.4121392 0.5983082 0.2265613
#> sample_5 0.6928714 0.5030906 0.6874645 0.4032932 0.5088547 0.3429312 0.4152152
#> sample_6 0.5061833 0.4758258 0.5895577 0.6649206 0.4697166 0.4513126 0.6012782
#> gene328 gene329 gene330 gene331 gene332 gene333 gene334
#> sample_1 0.3155875 0.5868980 0.4685258 0.4740232 0.16560222 0.4630168 0.6900826
#> sample_2 0.2549216 0.2992772 0.5944895 0.5944895 0.35752845 0.6677342 0.6412827
#> sample_3 0.3937349 0.2856459 0.6675411 0.5693291 0.37494994 0.6043721 0.6845335
#> sample_4 0.5156951 0.1597394 0.6955868 0.5276407 0.41213920 0.5216740 0.5276407
#> sample_5 0.1473380 0.4448060 0.4330062 0.5375033 0.02735565 0.3490247 0.2562403
#> sample_6 0.6877268 0.3954012 0.6476994 0.5362313 0.33840869 0.6245802 0.5242488
#> gene335 gene336 gene337 gene338 gene339 gene340 gene341
#> sample_1 0.3732710 0.3618348 0.00000000 0.7991069 0.3903327 0.5067694 0.7102436
#> sample_2 0.3575285 0.3430593 0.46411966 0.7329726 0.7715206 0.7070279 0.4360218
#> sample_3 0.5219386 0.3497131 0.70703675 0.7570414 0.4798288 0.7735204 0.7735204
#> sample_4 0.5808007 0.4306821 0.09826678 0.4674190 0.4856160 0.6330122 0.5216740
#> sample_5 0.3973136 0.5030906 0.23098432 0.4032932 0.5939592 0.6383402 0.5658696
#> sample_6 0.6934009 0.2737638 0.36387483 0.5061833 0.3954012 0.8209783 0.4635947
#> gene342 gene343 gene344 gene345 gene346 gene347 gene349
#> sample_1 0.4297192 0.5657674 0.6900826 0.6078606 0.6850182 0.6389952 0.3675591
#> sample_2 0.3575285 0.5058340 0.6743149 0.4500999 0.5674573 0.7458707 0.6346374
#> sample_3 0.5099693 0.6043721 0.6332554 0.6275017 0.5219386 0.6275017 0.4979505
#> sample_4 0.4121392 0.4976847 0.6330122 0.5513866 0.7678540 0.5513866 0.6272567
#> sample_5 0.2937136 0.4799182 0.4682616 0.3732704 0.4506878 0.4740958 0.4032932
#> sample_6 0.5001367 0.2672207 0.5362313 0.3511693 0.2868067 0.5362313 0.7439821
#> gene350 gene351 gene352 gene353 gene354 gene355 gene356
#> sample_1 0.6951373 0.5175950 0.7649040 0.4904471 0.5337505 0.5498075 0.5283763
#> sample_2 0.7070279 0.6012140 0.5877517 0.6545343 0.6677342 0.5470406 0.5264999
#> sample_3 0.6332554 0.2985728 0.6958069 0.7070368 0.5693291 0.7014272 0.4247761
#> sample_4 0.6729869 0.4976847 0.7458074 0.5924840 0.7678540 0.7678540 0.6157117
#> sample_5 0.4857288 0.4506878 0.6874645 0.5715095 0.7090314 0.5431990 0.5375033
#> sample_6 0.3447959 0.4574601 0.8209783 0.7159886 0.6419366 0.7159886 0.3638748
#> gene357 gene360 gene361 gene362 gene363 gene364 gene365
#> sample_1 0.8039570 0.5974002 0.5391137 0.6441487 0.2803616 0.6026356 0.6748601
#> sample_2 0.7070279 0.4850410 0.5742356 0.3139343 0.6012140 0.4218850 0.5264999
#> sample_3 0.5279048 0.5516480 0.5810571 0.4676846 0.7625447 0.4554895 0.4061912
#> sample_4 0.6843087 0.4306821 0.7291628 0.6272567 0.4674190 0.4121392 0.7897357
#> sample_5 0.4915277 0.6328299 0.6162352 0.5658696 0.3184276 0.5715095 0.7463889
#> sample_6 0.7103579 0.5718892 0.4203817 0.5122174 0.5481653 0.5600511 0.4819223
#> gene366 gene367 gene368 gene369 gene370 gene371
#> sample_1 0.7152598 0.50676937 0.5337505 0.07772642 0.4072847 0.4740232
#> sample_2 0.6079251 0.08712398 0.6874380 0.45009990 0.8907722 0.6146230
#> sample_3 0.5985608 0.55164802 0.5516480 0.80077951 0.6901757 0.7182234
#> sample_4 0.6729869 0.71242293 0.6041209 0.48561598 0.5097039 0.4059320
#> sample_5 0.3913216 0.50885468 0.2750379 0.11450802 0.3490247 0.2625198
#> sample_6 0.6071210 0.53623130 0.7717122 0.56597612 0.7047164 0.4203817
#> gene372 gene373 gene374 gene375 gene376 gene377 gene378
#> sample_1 0.4297192 0.3789705 0.4129113 0.3959955 0.4408652 0.4129113 0.2862654
#> sample_2 0.6012140 0.6479150 0.3647399 0.4919862 0.7070279 0.8033121 0.7458707
#> sample_3 0.7953481 0.2791609 0.2791609 0.3812251 0.7349232 0.9229823 0.2921165
#> sample_4 0.6041209 0.4795629 0.3431255 0.3746973 0.6272567 0.6729869 0.5335953
#> sample_5 0.4565577 0.6383402 0.4973149 0.1473380 0.5088547 0.4857288 0.5431990
#> sample_6 0.5481653 0.4203817 0.4203817 0.6591914 0.4451524 0.5600511 0.7047164
#> gene379 gene380 gene382 gene383 gene384 gene385 gene386
#> sample_1 0.5067694 0.5710660 0.5657674 0.6130753 0.1656022 0.6182797 0.6799440
#> sample_2 0.4641197 0.4571170 0.4780816 0.4989172 0.6545343 0.4005685 0.6479150
#> sample_3 0.6618548 0.4737630 0.5099693 0.3937349 0.8116120 0.6043721 0.5693291
#> sample_4 0.3809709 0.4976847 0.5983082 0.6041209 0.5924840 0.5690705 0.6387565
#> sample_5 0.5827562 0.1408019 0.3551053 0.4092604 0.4270880 0.7780284 0.4032932
#> sample_6 0.2933066 0.7439821 0.3062635 0.6934009 0.6245802 0.6419366 0.4940778
#> gene387 gene388 gene389 gene390 gene391 gene392 gene393
#> sample_1 0.7893799 0.3846577 0.5974002 0.8519735 0.3675591 0.5710660 0.3330255
#> sample_2 0.6412827 0.6412827 0.8845994 0.7523014 0.6479150 0.6677342 0.4641197
#> sample_3 0.4123994 0.4979505 0.3306407 0.6043721 0.2791609 0.8224044 0.8224044
#> sample_4 0.5866482 0.6272567 0.5216740 0.6616212 0.4674190 0.7568514 0.4856160
#> sample_5 0.5030906 0.2436400 0.3368248 0.6820475 0.3368248 0.6273089 0.4624156
#> sample_6 0.4697166 0.7772270 0.4880063 0.5302461 0.5954238 0.6591914 0.4574601
#> gene394 gene395 gene396 gene397 gene398 gene399 gene400
#> sample_1 0.3675591 0.3732710 0.4185258 0.5498075 0.33302546 0.6234739 0.5551382
#> sample_2 0.6677342 0.4989172 0.5333607 0.3358015 0.26977146 0.6611407 0.5538598
#> sample_3 0.9177746 0.5575537 0.6275017 0.5398006 0.59856082 0.5927379 0.8704804
#> sample_4 0.4916566 0.5572931 0.7235934 0.2397445 0.43068206 0.5513866 0.7180135
#> sample_5 0.2562403 0.4565577 0.5545566 0.4682616 0.04093662 0.4973149 0.5939592
#> sample_6 0.6706387 0.5541142 0.5541142 0.5422043 0.35116926 0.5954238 0.8587351
#> gene401 gene402 gene403 gene404 gene405 gene406 gene407
#> sample_1 0.4958991 0.5816312 0.5391137 0.6850182 0.7152598 0.4904471 0.5974002
#> sample_2 0.4147944 0.3430593 0.6874380 0.8845994 0.5196253 0.6677342 0.6146230
#> sample_3 0.6159599 0.1463282 0.4309448 0.6788804 0.6447289 0.7238007 0.7182234
#> sample_4 0.4795629 0.3112095 0.9488331 0.7842806 0.5335953 0.7347215 0.3934781
#> sample_5 0.4152152 0.2625198 0.4389121 0.4152152 0.5771384 0.3184276 0.3793000
#> sample_6 0.5122174 0.5122174 0.4697166 0.6187719 0.6419366 0.6820418 0.5836800
#> gene408 gene409 gene410 gene411 gene412 gene413 gene414
#> sample_1 0.5175950 0.6441487 0.3789705 0.6951373 0.5816312 0.6595491 0.3732710
#> sample_2 0.4571170 0.6012140 0.3647399 0.7394278 0.9458266 0.7523014 0.2623547
#> sample_3 0.7404685 0.7014272 0.5810571 0.5869034 0.6958069 0.6217365 0.8492113
#> sample_4 0.4734972 0.7180135 0.3112095 0.8650586 0.7733398 0.4245141 0.2000153
#> sample_5 0.4389121 0.5939592 0.4915277 0.7410817 0.7090314 0.1668578 0.1926801
#> sample_6 0.6187719 0.3511693 0.5061833 0.8747697 0.5182393 0.5718892 0.4327931
#> gene415 gene416 gene417 gene418 gene419 gene420 gene421
#> sample_1 0.6078606 0.8991309 0.7401988 0.4519643 0.5175950 0.3959955 0.4297192
#> sample_2 0.6146230 0.6939806 0.3212391 0.5538598 0.5538598 0.2845565 0.4571170
#> sample_3 0.6788804 0.6043721 0.4919225 0.4123994 0.8545432 0.2135028 0.3560429
#> sample_4 0.7788153 0.7733398 0.4059320 0.3431255 0.5983082 0.4121392 0.4183332
#> sample_5 0.5883632 0.6162352 0.3429312 0.4330062 0.5088547 0.2055049 0.3490247
#> sample_6 0.6071210 0.7216086 0.6476994 0.2737638 0.4513126 0.1672895 0.5895577
#> gene422 gene423 gene424 gene425 gene426 gene427 gene428
#> sample_1 0.2980334 0.6078606 0.4795092 0.4129113 0.6544256 0.5763539 0.6951373
#> sample_2 0.3430593 0.8348078 0.7394278 0.7329726 0.5058340 0.7458707 0.5402075
#> sample_3 0.4676846 0.7735204 0.5338588 0.8385182 0.3999697 0.4979505 0.5516480
#> sample_4 0.5156951 0.7180135 0.6214899 0.6955868 0.6157117 0.4734972 0.6444894
#> sample_5 0.2999120 0.2309843 0.1603659 0.4915277 0.3429312 0.5883632 0.3490247
#> sample_6 0.0000000 0.6534510 0.4697166 0.6591914 0.3702071 0.3511693 0.5659761
#> gene429 gene430 gene431 gene432 gene433 gene434 gene435
#> sample_1 0.6026356 0.3097491 0.3388126 0.3959955 0.5391137 0.6389952 0.6544256
#> sample_2 0.2175094 0.4360218 0.3862825 0.5196253 0.6479150 0.3862825 0.6146230
#> sample_3 0.3178559 0.5516480 0.1801094 0.8492113 0.7404685 0.8598653 0.5159601
#> sample_4 0.8060403 0.4734972 0.5395378 0.5924840 0.6387565 0.5631877 0.6502111
#> sample_5 0.4740958 0.2055049 0.3611731 0.4032932 0.6874645 0.5260780 0.3368248
#> sample_6 0.4327931 0.5422043 0.4697166 0.3765259 0.4697166 0.3127206 0.3191637
#> gene436 gene437 gene438 gene439 gene440 gene441 gene442
#> sample_1 0.4129113 0.2145323 0.3038978 0.4408652 0.6544256 0.4185258 0.5067694
#> sample_2 0.5606654 0.4218850 0.4076889 0.1491077 0.3647399 0.3212391 0.6874380
#> sample_3 0.6389978 0.5099693 0.3874867 0.6217365 0.6675411 0.3874867 0.9073310
#> sample_4 0.5454682 0.4183332 0.4368370 0.6330122 0.5335953 0.5216740 0.7347215
#> sample_5 0.3184276 0.1733351 0.1733351 0.3184276 0.5030906 0.3793000 0.5260780
#> sample_6 0.5777905 0.4265939 0.1942708 0.5362313 0.3255926 0.5541142 0.6591914
#> gene443 gene444 gene445 gene446 gene447 gene448 gene449
#> sample_1 0.23866084 0.5283763 0.5175950 0.5974002 0.4740232 0.7252637 0.5710660
#> sample_2 0.54020753 0.4711078 0.6939806 0.8348078 0.6611407 0.6213076 0.5333607
#> sample_3 0.69580689 0.5751990 0.2135028 0.3623589 0.4858819 0.2985728 0.5338588
#> sample_4 0.48561598 0.3367701 0.5395378 0.3367701 0.8060403 0.5631877 0.5631877
#> sample_5 0.43891212 0.3060971 0.5317963 0.3853171 0.8300002 0.6874645 0.5658696
#> sample_6 0.06385131 0.6591914 0.5541142 0.2933066 0.5122174 0.3954012 0.1468902
#> gene450 gene451 gene452 gene454 gene455 gene456 gene457
#> sample_1 0.3272256 0.5283763 0.8136305 0.4849839 0.4408652 0.2862654 0.5921543
#> sample_2 0.6545343 0.4989172 0.6743149 0.4289608 0.3212391 0.3575285 0.7329726
#> sample_3 0.5099693 0.5099693 0.5693291 0.4247761 0.6732162 0.2596186 0.8863307
#> sample_4 0.3557951 0.2983450 0.6843087 0.5808007 0.7458074 0.2659341 0.6272567
#> sample_5 0.3973136 0.2750379 0.5883632 0.3060971 0.5658696 0.1473380 0.5375033
#> sample_6 0.4327931 0.4451524 0.5718892 0.5777905 0.5718892 0.2933066 0.4513126
#> gene458 gene459 gene460 gene461 gene462 gene463 gene464
#> sample_1 0.4016462 0.2625706 0.6338315 0.5013398 0.7451584 0.4519643 0.4464206
#> sample_2 0.4147944 0.2400063 0.8348078 0.3575285 0.7715206 0.4360218 0.7005105
#> sample_3 0.6159599 0.3497131 0.7625447 0.6217365 0.6561574 0.7293672 0.3433695
#> sample_4 0.5276407 0.6673096 0.6843087 0.7124229 0.7068216 0.6272567 0.4552245
#> sample_5 0.2625198 0.3184276 0.3551053 0.6820475 0.4270880 0.6982681 0.3913216
#> sample_6 0.5182393 0.3765259 0.7991838 0.5541142 0.6990641 0.5242488 0.4574601
#> gene465 gene466 gene467 gene468 gene469 gene470 gene471
#> sample_1 0.4185258 0.5175950 0.4408652 0.3214130 0.5067694 0.7202665 0.4740232
#> sample_2 0.4218850 0.4571170 0.3719360 0.2697715 0.5538598 0.4500999 0.6213076
#> sample_3 0.7625447 0.4493727 0.5219386 0.3623589 0.5398006 0.7349232 0.6043721
#> sample_4 0.6673096 0.6502111 0.4306821 0.4059320 0.3684101 0.7788153 0.5395378
#> sample_5 0.2246356 0.6328299 0.3853171 0.1538593 0.6874645 0.5375033 0.4032932
#> sample_6 0.5895577 0.2933066 0.6591914 0.4574601 0.4327931 0.6591914 0.4635947
#> gene472 gene473 gene474 gene475 gene476 gene477 gene478
#> sample_1 0.2980334 0.6338315 0.5444660 0.2506428 0.6286578 0.4352981 0.4297192
#> sample_2 0.2919249 0.3212391 0.5470406 0.3212391 0.2992772 0.4780816 0.1567765
#> sample_3 0.4123994 0.4979505 0.7070368 0.3686612 0.5575537 0.5159601 0.4737630
#> sample_4 0.4734972 0.5037005 0.6729869 0.4916566 0.5513866 0.6843087 0.3746973
#> sample_5 0.3672281 0.5431990 0.4448060 0.1408019 0.6162352 0.5939592 0.3793000
#> sample_6 0.6071210 0.5541142 0.3575289 0.4635947 0.3702071 0.5541142 0.5777905
#> gene479 gene480 gene481 gene482 gene483 gene484 gene485
#> sample_1 0.6697663 0.3959955 0.2744446 0.3846577 0.4685258 0.5067694 0.7698174
#> sample_2 0.1872791 0.5944895 0.7842731 0.6346374 0.2250250 0.2024280 0.3791168
#> sample_3 0.3306407 0.1395246 0.7735204 0.4371004 0.2267535 0.8007795 0.3497131
#> sample_4 0.3809709 0.3746973 0.6387565 0.3621094 0.7180135 0.6272567 0.4856160
#> sample_5 0.4389121 0.4857288 0.3913216 0.2687857 0.3611731 0.2118959 0.2687857
#> sample_6 0.5481653 0.2672207 0.6649206 0.4451524 0.3511693 0.5895577 0.3954012
#> gene486 gene487 gene488 gene489 gene490 gene491 gene492
#> sample_1 0.6544256 0.6595491 0.5604582 0.5391137 0.5175950 0.5551382 0.4408652
#> sample_2 0.3862825 0.5402075 0.4500999 0.2845565 0.4919862 0.5538598 0.4430682
#> sample_3 0.6845335 0.6901757 0.6618548 0.4123994 0.5516480 0.4309448 0.5398006
#> sample_4 0.5097039 0.6502111 0.5983082 0.4429790 0.8168598 0.4613281 0.4734972
#> sample_5 0.2182728 0.5431990 0.8556385 0.3368248 0.4682616 0.4682616 0.1990996
#> sample_6 0.5954238 0.5481653 0.6877268 0.5001367 0.5718892 0.6934009 0.5718892
#> gene493 gene494 gene495 gene496 gene497 gene498 gene499
#> sample_1 0.2266242 0.5013398 0.2084654 0.3675591 0.4519643 0.5921543 0.7401988
#> sample_2 0.3934330 0.6939806 0.6479150 0.5196253 0.1414215 0.6545343 0.6874380
#> sample_3 0.2856459 0.5751990 0.3623589 0.4798288 0.6561574 0.7182234 0.5751990
#> sample_4 0.4245141 0.4306821 0.3304009 0.4121392 0.5395378 0.6041209 0.5395378
#> sample_5 0.3551053 0.4448060 0.3611731 0.3793000 0.2309843 0.5375033 0.4915277
#> sample_6 0.3828311 0.6129522 0.3702071 0.2276538 0.2737638 0.6012782 0.5541142
#> gene500 gene501 gene502 gene503 gene504 gene505 gene506
#> sample_1 0.5868980 0.7401988 0.3846577 0.5763539 0.7942479 0.6595491 0.4241284
#> sample_2 0.5264999 0.6939806 0.5810004 0.3862825 0.4641197 0.7715206 0.2325239
#> sample_3 0.4309448 0.4979505 0.8810568 0.3999697 0.3623589 0.8385182 0.3560429
#> sample_4 0.2265613 0.6444894 0.3367701 0.5513866 0.5216740 0.9281132 0.2789416
#> sample_5 0.4270880 0.4857288 0.3245731 0.0000000 0.6162352 0.6328299 0.3793000
#> sample_6 0.6129522 0.8155448 0.4574601 0.5061833 0.4940778 0.7772270 0.4758258
#> gene507 gene508 gene509 gene510 gene511 gene512 gene513
#> sample_1 0.7501087 0.8614727 0.7202665 0.5444660 0.4795092 0.5175950 0.5391137
#> sample_2 0.5196253 0.5742356 0.5470406 0.3212391 0.6346374 0.9153514 0.5470406
#> sample_3 0.6447289 0.5099693 0.4554895 0.9229823 0.6675411 0.4554895 0.6845335
#> sample_4 0.6899532 0.5983082 0.6729869 0.3240177 0.5924840 0.7124229 0.8437349
#> sample_5 0.5317963 0.2812766 0.4389121 0.2436400 0.5995444 0.5658696 0.7569741
#> sample_6 0.4819223 0.3891228 0.3127206 0.3702071 0.3954012 0.4880063 0.3320076
#> gene514 gene515 gene516 gene517 gene518 gene519 gene520
#> sample_1 0.6799440 0.4408652 0.5604582 0.4016462 0.4072847 0.6234739 0.2921560
#> sample_2 0.7070279 0.5402075 0.4571170 0.6346374 0.2400063 0.8033121 0.1948620
#> sample_3 0.3999697 0.4123994 0.3497131 0.6275017 0.2856459 0.2465171 0.5693291
#> sample_4 0.6444894 0.5983082 0.3240177 0.6502111 0.6729869 0.3304009 0.4368370
#> sample_5 0.5317963 0.3672281 0.6657349 0.4448060 0.1926801 0.1862462 0.5431990
#> sample_6 0.7551054 0.4940778 0.5302461 0.3765259 0.3191637 0.5600511 0.5777905
#> gene521 gene522 gene523 gene524 gene525 gene526 gene527
#> sample_1 0.6182797 0.5337505 0.5175950 0.5175950 0.4795092 0.6697663 0.4685258
#> sample_2 0.7394278 0.4005685 0.6677342 0.6346374 0.5810004 0.5944895 0.5470406
#> sample_3 0.6217365 0.5219386 0.6217365 0.4493727 0.8545432 0.4371004 0.7182234
#> sample_4 0.5097039 0.6041209 0.5395378 0.3809709 0.4059320 0.6955868 0.0913561
#> sample_5 0.5030906 0.4270880 0.5771384 0.3429312 0.5488834 0.5030906 0.3973136
#> sample_6 0.6012782 0.6591914 0.8155448 0.5600511 0.4880063 0.4141564 0.7551054
#> gene529 gene530 gene531 gene533 gene534 gene535 gene536
#> sample_1 0.7302515 0.4795092 0.4685258 0.4685258 0.6748601 0.3846577 0.6130753
#> sample_2 0.6012140 0.3285281 0.2623547 0.6545343 0.5333607 0.3719360 0.4218850
#> sample_3 0.4858819 0.7014272 0.6332554 0.5634473 0.7293672 0.2985728 0.4919225
#> sample_4 0.5631877 0.6843087 0.5335953 0.5156951 0.6673096 0.4976847 0.3240177
#> sample_5 0.3672281 0.3429312 0.3551053 0.4740958 0.4799182 0.6928714 0.5030906
#> sample_6 0.6649206 0.6990641 0.6071210 0.4635947 0.4016662 0.5895577 0.3954012
#> gene537 gene538 gene539 gene540 gene541 gene543 gene544
#> sample_1 0.6338315 0.4185258 0.4408652 0.5604582 0.5391137 0.5444660 0.5498075
#> sample_2 0.8784154 0.2474721 0.4850410 0.6279791 0.5674573 0.4989172 0.7779028
#> sample_3 0.6675411 0.5985608 0.6043721 0.4554895 0.6275017 0.5927379 0.5810571
#> sample_4 0.8914967 0.7012096 0.4916566 0.4245141 0.7458074 0.3621094 0.4795629
#> sample_5 0.6602768 0.3368248 0.3672281 0.5995444 0.4330062 0.3853171 0.3732704
#> sample_6 0.3828311 0.6303770 0.4389792 0.9118480 0.6187719 0.5362313 0.5954238
#> gene545 gene546 gene547 gene548 gene549 gene550 gene551
#> sample_1 0.2506428 0.6799440 0.6492922 0.6544256 0.6026356 0.6182797 0.8087982
#> sample_2 0.6677342 0.4147944 0.3430593 0.5877517 0.6412827 0.5058340 0.5470406
#> sample_3 0.6845335 0.4554895 0.5751990 0.5693291 0.5634473 0.7735204 0.5751990
#> sample_4 0.8437349 0.7235934 0.6444894 0.7012096 0.6330122 0.6330122 0.9176980
#> sample_5 0.2875018 0.5545566 0.4624156 0.6711827 0.4915277 0.5715095 0.4973149
#> sample_6 0.7772270 0.5001367 0.5422043 0.6990641 0.7272179 0.7384046 0.7328166
#> gene552 gene553 gene554 gene555 gene556 gene557 gene558
#> sample_1 0.4849839 0.5229911 0.7451584 0.6441487 0.6338315 0.5067694 0.5229911
#> sample_2 0.5674573 0.7906313 0.6545343 0.7523014 0.4218850 0.4989172 0.7200251
#> sample_3 0.6732162 0.8915950 0.5751990 0.8492113 0.7126355 0.4123994 0.7404685
#> sample_4 0.7068216 0.6330122 0.7897357 0.7842806 0.3746973 0.4121392 0.7842806
#> sample_5 0.2373191 0.5203484 0.3913216 0.5317963 0.5375033 0.3611731 0.7357647
#> sample_6 0.6419366 0.4141564 0.5718892 0.3954012 0.5718892 0.3954012 0.6706387
#> gene559 gene560 gene561 gene562 gene563 gene564 gene565
#> sample_1 0.4740232 0.6286578 0.6748601 0.6544256 0.5498075 0.8087982 0.9909879
#> sample_2 0.3719360 0.6479150 0.4005685 0.5674573 0.6545343 0.6874380 0.7458707
#> sample_3 0.7625447 0.6217365 0.3874867 0.8170132 0.7625447 0.2921165 0.3497131
#> sample_4 0.6444894 0.5335953 0.4183332 0.2331603 0.7235934 0.5983082 0.9124765
#> sample_5 0.5939592 0.3368248 0.4211577 0.3913216 0.6820475 0.6106824 0.6602768
#> sample_6 0.6187719 0.4389792 0.5481653 0.5001367 0.5122174 0.2409019 0.7047164
#> gene566 gene567 gene568 gene569 gene571 gene572 gene574
#> sample_1 0.6234739 0.6492922 0.4685258 0.3445870 0.5868980 0.5013398 0.7302515
#> sample_2 0.5538598 0.5606654 0.3503016 0.3503016 0.4218850 0.6479150 0.4919862
#> sample_3 0.5279048 0.6389978 0.2135028 0.6043721 0.5338588 0.6732162 0.6332554
#> sample_4 0.7513346 0.7623579 0.1597394 0.1664906 0.3431255 0.5037005 0.3997117
#> sample_5 0.3732704 0.2625198 0.2687857 0.5488834 0.2625198 0.6162352 0.6982681
#> sample_6 0.3954012 0.5302461 0.1468902 0.2868067 0.2802925 0.4451524 0.7103579
#> gene575 gene576 gene577 gene578 gene579 gene580
#> sample_1 0.6286578 0.3846577 0.4016462 0.2980334 0.41291126 0.6441487
#> sample_2 0.7842731 0.5333607 0.5674573 0.4500999 0.03194144 0.4500999
#> sample_3 0.5927379 0.7899065 0.3497131 0.4123994 0.44937270 0.6845335
#> sample_4 0.7568514 0.5866482 0.4245141 0.6330122 0.44297901 0.3872312
#> sample_5 0.3307055 0.6106824 0.1538593 0.4270880 0.35510528 0.3307055
#> sample_6 0.4203817 0.3255926 0.3255926 0.5954238 0.49407775 0.4635947
#> gene581 gene582 gene583 gene584 gene585 gene586 gene587
#> sample_1 0.09046088 0.3618348 0.4685258 0.4849839 0.2862654 0.4072847 0.5868980
#> sample_2 0.65453428 0.3791168 0.5810004 0.2400063 0.5196253 0.4780816 0.5810004
#> sample_3 0.72380067 0.6845335 0.4432430 0.3306407 0.3999697 0.8598653 0.6217365
#> sample_4 0.64448940 0.5983082 0.7124229 0.4121392 0.4734972 0.5513866 1.0000000
#> sample_5 0.43300615 0.1408019 0.4092604 0.5602187 0.2812766 0.2937136 0.5488834
#> sample_6 0.22765384 0.5718892 0.5895577 0.6129522 0.1056632 0.4451524 0.3891228
#> gene588 gene589 gene590 gene591 gene592 gene593 gene594
#> sample_1 0.6389952 0.5657674 0.5121877 0.6595491 0.6286578 0.6799440 0.4904471
#> sample_2 0.6213076 0.3862825 0.5058340 0.5538598 0.4919862 0.3285281 0.7070279
#> sample_3 0.5810571 0.5634473 0.6901757 0.6504488 0.5219386 0.4371004 0.7014272
#> sample_4 0.5983082 0.5690705 0.4429790 0.4491082 0.5866482 0.5572931 0.5749415
#> sample_5 0.6928714 0.2687857 0.4915277 0.4092604 0.4915277 0.3307055 0.4682616
#> sample_6 0.5541142 0.5182393 0.7384046 0.7159886 0.6361625 0.4574601 0.6245802
#> gene595 gene596 gene598 gene599 gene600 gene601 gene602
#> sample_1 0.4408652 0.4352981 0.5444660 0.4185258 0.5816312 0.6850182 0.5229911
#> sample_2 0.4500999 0.6279791 0.6874380 0.7135327 0.7394278 0.3791168 0.4147944
#> sample_3 0.5693291 0.6788804 0.7625447 0.8438696 0.6101717 0.3370120 0.7844547
#> sample_4 0.2724451 0.4734972 0.4674190 0.8437349 0.5572931 0.7568514 0.4121392
#> sample_5 0.2309843 0.4092604 0.4448060 0.4740958 0.4330062 0.3973136 0.4740958
#> sample_6 0.5001367 0.5954238 0.5001367 0.5600511 0.6012782 0.5836800 0.3702071
#> gene603 gene604 gene605 gene606 gene607 gene608 gene609
#> sample_1 0.7102436 0.6951373 0.5604582 0.6078606 0.6078606 0.2266242 0.5175950
#> sample_2 0.5402075 0.7135327 0.3862825 0.5402075 0.6012140 0.4218850 0.4147944
#> sample_3 0.7953481 0.4371004 0.5985608 0.6389978 0.7182234 0.6504488 0.5985608
#> sample_4 0.6272567 0.3304009 0.6559217 0.5156951 0.3746973 0.4976847 0.4183332
#> sample_5 0.6273089 0.3732704 0.4682616 0.3368248 0.5375033 0.3184276 0.5883632
#> sample_6 0.6706387 0.5242488 0.5302461 0.3320076 0.6591914 0.5362313 0.6763458
#> gene610 gene611 gene612 gene613 gene614 gene615 gene616
#> sample_1 0.6182797 0.5391137 0.4519643 0.2446586 0.7252637 0.4904471 0.4519643
#> sample_2 0.2845565 0.4919862 0.6279791 0.4919862 0.6611407 0.5264999 0.1182577
#> sample_3 0.4615934 0.7789927 0.7899065 0.3812251 0.4919225 0.5810571 0.5751990
#> sample_4 0.4552245 0.6729869 0.9072456 0.5866482 0.7012096 0.4245141 0.1664906
#> sample_5 0.3429312 0.5488834 0.4624156 0.5715095 0.5939592 0.2373191 0.2812766
#> sample_6 0.7772270 0.8587351 0.5302461 0.1400590 0.8101012 0.5777905 0.1537057
#> gene617 gene618 gene619 gene620 gene621 gene622 gene623
#> sample_1 0.5013398 0.7401988 0.32722561 0.4352981 0.7401988 0.3560981 0.7401988
#> sample_2 0.6939806 0.6079251 0.35752845 0.4919862 0.5944895 0.2771720 0.8096347
#> sample_3 0.6447289 0.7460033 0.80620081 0.5279048 0.5693291 0.5869034 0.6618548
#> sample_4 0.4121392 0.4306821 0.33040085 0.7568514 0.4245141 0.6214899 0.6673096
#> sample_5 0.5883632 0.2436400 0.02735565 0.5146073 0.2055049 0.4389121 0.6273089
#> sample_6 0.4265939 0.5600511 0.60127818 0.3638748 0.4451524 0.5242488 0.5777905
#> gene624 gene625 gene626 gene627 gene628 gene629 gene630
#> sample_1 0.3789705 0.5498075 0.5498075 0.4849839 0.7796168 0.5868980 0.6026356
#> sample_2 0.6479150 0.5196253 0.3719360 0.5333607 0.7779028 0.5058340 0.6079251
#> sample_3 0.5927379 0.6845335 0.7515276 0.5751990 0.7570414 0.5693291 0.3497131
#> sample_4 0.1664906 0.5395378 0.3746973 0.6330122 0.9745284 0.4613281 0.4734972
#> sample_5 0.2499470 0.6657349 0.5939592 0.4152152 0.5827562 0.2562403 0.4915277
#> sample_6 0.5182393 0.4203817 0.3765259 0.4451524 0.9743455 0.4635947 0.6649206
#> gene631 gene632 gene633 gene634 gene635 gene636 gene637
#> sample_1 0.5974002 0.5974002 0.4795092 0.5067694 0.5657674 0.4185258 0.6799440
#> sample_2 0.5058340 0.4571170 0.2474721 0.2919249 0.6412827 0.4360218 0.5196253
#> sample_3 0.5457304 0.6389978 0.3306407 0.7680377 0.6159599 0.7953481 0.5279048
#> sample_4 0.5335953 0.4976847 0.4674190 0.2918915 0.7180135 0.5749415 0.6616212
#> sample_5 0.7304379 0.5545566 0.4389121 0.1342509 0.5545566 0.4211577 0.5203484
#> sample_6 0.5302461 0.6187719 0.8264018 0.5182393 0.4880063 0.3891228 0.6361625
#> gene638 gene639 gene640 gene641 gene642 gene643 gene644
#> sample_1 0.5013398 0.5816312 0.4072847 0.3959955 0.4904471 0.4519643 0.5337505
#> sample_2 0.6012140 0.5877517 0.6012140 0.2845565 0.8033121 0.7005105 0.4500999
#> sample_3 0.7014272 0.7515276 0.2465171 0.6217365 0.8331568 0.5927379 0.3433695
#> sample_4 0.5156951 0.8060403 0.4552245 0.7513346 0.3494672 0.5808007 0.8756625
#> sample_5 0.5602187 0.5030906 0.2055049 0.3122689 0.6217774 0.5030906 0.4506878
#> sample_6 0.7937099 0.8101012 0.5836800 0.5954238 0.5182393 0.3511693 0.4880063
#> gene645 gene646 gene647 gene648 gene649 gene650 gene651
#> sample_1 0.6338315 0.6748601 0.3272256 0.4464206 0.6595491 0.6441487 0.5974002
#> sample_2 0.8597952 0.7005105 0.6545343 0.6146230 0.5058340 0.6743149 0.8348078
#> sample_3 0.3999697 0.5219386 0.4919225 0.7789927 0.7070368 0.6958069 0.8062008
#> sample_4 0.8114551 0.7458074 0.2789416 0.3304009 0.6559217 0.7842806 0.6444894
#> sample_5 0.5939592 0.7143979 0.2373191 0.5203484 0.6548083 0.5146073 0.6217774
#> sample_6 0.5600511 0.6012782 0.3127206 0.3891228 0.2143460 0.4697166 0.7661870
#> gene652 gene653 gene654 gene655 gene656 gene657 gene658
#> sample_1 0.5498075 0.4352981 0.5283763 0.5337505 0.6697663 0.5121877 0.5444660
#> sample_2 0.3862825 0.4147944 0.7005105 0.5742356 0.4218850 0.6874380 0.2623547
#> sample_3 0.5751990 0.4432430 0.4979505 0.7789927 0.4676846 0.9177746 0.7515276
#> sample_4 0.5097039 0.5156951 0.6444894 0.5983082 0.4976847 0.4183332 0.7291628
#> sample_5 0.7357647 0.4270880 0.8145069 0.4330062 0.3368248 0.5030906 0.2309843
#> sample_6 0.4451524 0.1740581 0.5895577 0.4079179 0.6990641 0.5122174 0.5481653
#> gene659 gene660 gene661 gene662 gene663 gene664 gene665
#> sample_1 0.4185258 0.6389952 0.5498075 0.4185258 0.3445870 0.4129113 0.5710660
#> sample_2 0.2024280 0.5470406 0.6939806 0.7651263 0.5674573 0.1567765 0.5196253
#> sample_3 0.7844547 0.3686612 0.7014272 0.7293672 0.6101717 0.3623589 0.5159601
#> sample_4 0.4183332 0.4613281 0.7124229 0.4245141 0.3431255 0.3112095 0.6502111
#> sample_5 0.1668578 0.5658696 0.6602768 0.6383402 0.5715095 0.1862462 0.4799182
#> sample_6 0.4451524 0.7551054 0.3191637 0.5061833 0.4451524 0.3384087 0.4265939
#> gene666 gene667 gene668 gene669 gene670 gene671 gene672
#> sample_1 0.4352981 0.6697663 0.5921543 0.36755909 0.6951373 0.5444660 0.6078606
#> sample_2 0.5538598 0.9760299 0.3503016 0.00000000 0.4500999 0.4360218 0.6611407
#> sample_3 0.5927379 0.7404685 0.7293672 0.15988782 0.7735204 0.5159601 0.6504488
#> sample_4 0.7458074 0.5924840 0.6272567 0.34312553 0.5749415 0.6387565 0.9229103
#> sample_5 0.5939592 0.5771384 0.2562403 0.01371031 0.2562403 0.5030906 0.4270880
#> sample_6 0.6129522 0.6877268 0.5302461 0.15370570 0.5362313 0.7103579 0.6990641
#> gene673 gene674 gene675 gene676 gene678 gene679 gene680
#> sample_1 0.4574963 0.3445870 0.6646627 0.4519643 0.4685258 0.5283763 0.7747216
#> sample_2 0.5877517 0.5470406 0.7842731 0.3719360 0.6677342 0.2400063 0.6545343
#> sample_3 0.4615934 0.6275017 0.4061912 0.7349232 0.5985608 0.7238007 0.4615934
#> sample_4 0.5454682 0.4491082 0.6616212 0.3746973 0.4976847 0.4734972 0.4552245
#> sample_5 0.1668578 0.4682616 0.6051188 0.4330062 0.3184276 0.2118959 0.6051188
#> sample_6 0.4016662 0.6419366 0.5481653 0.5836800 0.5182393 0.4079179 0.3255926
#> gene681 gene682 gene683 gene684 gene685 gene686 gene687
#> sample_1 0.5391137 0.5013398 0.4352981 0.5175950 0.50676937 0.3388126 0.6078606
#> sample_2 0.2771720 0.3139343 0.2549216 0.4989172 0.41479439 0.7200251 0.3285281
#> sample_3 0.1395246 0.5575537 0.5985608 0.6217365 0.41859431 0.2201357 0.5869034
#> sample_4 0.5156951 0.5276407 0.3304009 0.5037005 0.44297901 0.6616212 0.4183332
#> sample_5 0.3793000 0.2999120 0.4270880 0.4799182 0.07461139 0.3611731 0.4330062
#> sample_6 0.5777905 0.2540907 0.4451524 0.6934009 0.56597612 0.5302461 0.6129522
#> gene689 gene690 gene691 gene692 gene693 gene694 gene695
#> sample_1 0.3675591 0.3846577 0.4185258 0.5816312 0.4685258 0.5604582 0.25064282
#> sample_2 0.4850410 0.5470406 0.4289608 0.5877517 0.5944895 0.3934330 0.05570131
#> sample_3 0.4554895 0.3560429 0.5159601 0.4737630 0.7349232 0.5398006 0.50996928
#> sample_4 0.4916566 0.3557951 0.5454682 0.7623579 0.6214899 0.4059320 0.04954580
#> sample_5 0.2309843 0.2999120 0.3732704 0.2182728 0.4270880 0.5030906 0.30609711
#> sample_6 0.2997922 0.5001367 0.3765259 0.5718892 0.5422043 0.4016662 0.37652587
#> gene696 gene697 gene698 gene699 gene700 gene701 gene702
#> sample_1 0.5498075 1.0000000 0.5974002 0.7649040 0.5974002 0.3272256 0.5067694
#> sample_2 0.7394278 0.6743149 0.5810004 0.7842731 0.8033121 0.2024280 0.7458707
#> sample_3 0.6618548 0.5927379 0.6389978 0.8224044 0.4371004 0.7570414 0.6901757
#> sample_4 0.5395378 0.8437349 0.5454682 0.5037005 0.5808007 0.6041209 0.6214899
#> sample_5 0.6982681 0.7251011 0.6106824 0.4624156 0.3672281 0.4624156 0.4624156
#> sample_6 0.4940778 0.5954238 0.7661870 0.5541142 0.5777905 0.6012782 0.5836800
#> gene703 gene704 gene705 gene706 gene707 gene708 gene709
#> sample_1 0.8709378 0.5283763 0.6544256 0.4241284 0.7102436 0.6900826 0.5444660
#> sample_2 0.5742356 0.4711078 0.6412827 0.5877517 0.2992772 0.6874380 0.3791168
#> sample_3 0.4432430 0.4798288 0.8331568 0.2068547 0.9073310 0.7625447 0.5219386
#> sample_4 0.8168598 0.3809709 0.6041209 0.4856160 0.6502111 0.6157117 0.1799466
#> sample_5 0.6438400 0.3184276 0.5771384 0.3853171 0.6328299 0.5317963 0.1538593
#> sample_6 0.5895577 0.1875486 0.8372190 0.4141564 0.6877268 0.5659761 0.4635947
#> gene710 gene711 gene712 gene713 gene715 gene716 gene718
#> sample_1 0.5013398 0.5391137 0.4574963 0.6130753 0.5763539 0.4185258 0.3330255
#> sample_2 0.7779028 0.6808828 0.3934330 0.3862825 0.6479150 0.4571170 0.3575285
#> sample_3 0.5751990 0.9437206 0.4554895 0.7182234 0.8651777 0.4185943 0.6788804
#> sample_4 0.5866482 0.4613281 0.5866482 0.5216740 0.7180135 0.3112095 0.5690705
#> sample_5 0.4506878 0.5030906 0.1990996 0.4915277 0.8093239 0.3793000 0.4973149
#> sample_6 0.5777905 0.5777905 0.5061833 0.6303770 0.6763458 0.3765259 0.5422043
#> gene719 gene720 gene721 gene722 gene723 gene725 gene726
#> sample_1 0.7796168 0.3732710 0.5175950 0.5868980 0.7796168 0.4072847 0.4129113
#> sample_2 0.4850410 0.2623547 0.7969776 0.5674573 0.7005105 0.3791168 0.4850410
#> sample_3 0.6447289 0.5279048 0.5338588 0.2661473 0.8385182 0.3999697 0.7014272
#> sample_4 0.5395378 0.2528686 0.8490804 0.6843087 0.6616212 0.4491082 0.4059320
#> sample_5 0.4973149 0.1603659 0.6383402 0.4682616 0.6106824 0.2373191 0.2812766
#> sample_6 0.3191637 0.5001367 0.5954238 0.3191637 0.5895577 0.4016662 0.4265939
#> gene727 gene728 gene729 gene731 gene732 gene733 gene734
#> sample_1 0.3560981 0.3675591 0.5551382 0.5121877 0.5337505 0.6492922 0.7202665
#> sample_2 0.3212391 0.4780816 0.7265050 0.4850410 0.6346374 0.5810004 0.6012140
#> sample_3 0.5927379 0.8598653 0.8968498 0.5039661 0.5099693 0.7014272 0.3812251
#> sample_4 0.6899532 0.5690705 0.6955868 0.3621094 0.5924840 0.3367701 0.6843087
#> sample_5 0.3853171 0.4565577 0.6602768 0.5995444 0.4270880 0.5545566 0.5260780
#> sample_6 0.5718892 0.6187719 0.5182393 0.6361625 0.3575289 0.4940778 0.5777905
#> gene735 gene736 gene737 gene738 gene740 gene741 gene742
#> sample_1 0.6286578 0.4740232 0.3388126 0.4519643 0.3732710 0.6286578 0.3272256
#> sample_2 0.5538598 0.8969338 0.1337178 0.7587200 0.4780816 0.4641197 0.4147944
#> sample_3 0.5279048 0.8492113 0.3874867 0.7680377 0.4554895 0.6788804 0.3812251
#> sample_4 0.4183332 0.6099220 0.5216740 0.7068216 0.4674190 0.3746973 0.4674190
#> sample_5 0.4211577 0.6928714 0.2499470 0.3184276 0.2875018 0.3122689 0.1926801
#> sample_6 0.5600511 0.6820418 0.1537057 0.8854112 0.5600511 0.4016662 0.2868067
#> gene743 gene744 gene745 gene746 gene747 gene748 gene749
#> sample_1 0.5868980 0.5121877 0.5921543 0.3388126 0.5391137 0.6799440 0.5013398
#> sample_2 0.9153514 0.4780816 0.6412827 0.4218850 0.6874380 0.4360218 0.5810004
#> sample_3 0.6159599 0.2921165 0.6845335 0.6043721 0.5457304 0.3114424 0.6043721
#> sample_4 0.5276407 0.4795629 0.7180135 0.2463139 0.5335953 0.5395378 0.7124229
#> sample_5 0.7036548 0.5203484 0.3672281 0.4389121 0.6438400 0.4448060 0.3551053
#> sample_6 0.5302461 0.6071210 0.8372190 0.5954238 0.4141564 0.8101012 0.5422043
#> gene750 gene751 gene752 gene753 gene754 gene755 gene756
#> sample_1 0.5444660 0.6338315 0.4016462 0.8424399 0.4740232 0.3732710 0.3560981
#> sample_2 0.7906313 0.9880361 0.1644280 0.5058340 0.3647399 0.4571170 0.7906313
#> sample_3 0.5985608 0.7182234 0.3812251 0.6159599 0.3178559 0.6504488 0.4247761
#> sample_4 0.5690705 0.7458074 0.7951807 0.5037005 0.4734972 0.4491082 0.6843087
#> sample_5 0.5545566 0.8248450 0.4211577 0.4565577 0.2687857 0.4682616 0.4506878
#> sample_6 0.6591914 0.6877268 0.3954012 0.2997922 0.3765259 0.4016662 0.3765259
#> gene757 gene759 gene760 gene761 gene762 gene763 gene764
#> sample_1 0.4740232 0.4519643 0.7649040 0.5121877 0.1594216 0.5868980 0.6697663
#> sample_2 0.5402075 0.6012140 0.2099771 0.4430682 0.4076889 0.9820383 0.4430682
#> sample_3 0.6732162 0.8331568 0.4798288 0.4919225 0.4309448 0.7570414 0.5099693
#> sample_4 0.6729869 0.6099220 0.3367701 0.3304009 0.4245141 0.5097039 0.7124229
#> sample_5 0.5260780 0.6602768 0.5883632 0.4092604 0.1797979 0.4624156 0.6766202
#> sample_6 0.4697166 0.6071210 0.4697166 0.5481653 0.2868067 0.4203817 0.3638748
#> gene765 gene766 gene768 gene769 gene770 gene771 gene772
#> sample_1 0.3097491 0.6286578 0.3618348 0.5498075 0.5657674 0.5067694 0.4297192
#> sample_2 0.5810004 0.2623547 0.5402075 0.5944895 0.7005105 0.6743149 0.6677342
#> sample_3 0.6101717 0.6332554 0.5634473 0.6217365 0.6732162 0.5693291 0.7014272
#> sample_4 0.4368370 0.7068216 0.4856160 0.4916566 0.4491082 0.7012096 0.5454682
#> sample_5 0.4092604 0.2687857 0.5545566 0.5088547 0.3913216 0.3307055 0.6106824
#> sample_6 0.3765259 0.6534510 0.4758258 0.5242488 0.6763458 0.5954238 0.4513126
#> gene773 gene774 gene775 gene776 gene777 gene778 gene779
#> sample_1 0.7052178 0.4241284 0.4849839 0.5121877 0.7302515 0.4241284 0.6338315
#> sample_2 0.6545343 0.4147944 0.6677342 0.5742356 0.5606654 0.5196253 0.5944895
#> sample_3 0.6275017 0.7625447 0.6732162 0.5338588 0.6332554 0.7070368 0.6332554
#> sample_4 0.5572931 0.3367701 0.4795629 0.5572931 0.6214899 0.5924840 0.4429790
#> sample_5 0.4740958 0.3368248 0.5883632 0.4330062 0.4624156 0.5488834 0.6106824
#> sample_6 0.6476994 0.5422043 0.3384087 0.4940778 0.1808111 0.8046476 0.6706387
#> gene780 gene781 gene782 gene783 gene784 gene785 gene786
#> sample_1 0.5763539 0.6748601 0.4685258 0.5013398 0.6595491 0.4795092 0.7202665
#> sample_2 0.6146230 0.6479150 0.4711078 0.6743149 0.5944895 0.4218850 0.3139343
#> sample_3 0.4737630 0.5219386 0.3874867 0.6043721 0.5634473 0.5338588 0.7789927
#> sample_4 0.5924840 0.5037005 0.5097039 0.3934781 0.4183332 0.7068216 0.5335953
#> sample_5 0.6438400 0.6051188 0.3490247 0.3122689 0.4211577 0.4624156 0.6273089
#> sample_6 0.4574601 0.8264018 0.2540907 0.3127206 0.2210074 0.4141564 0.2606630
#> gene787 gene788 gene789 gene790 gene791 gene792 gene793
#> sample_1 0.3330255 0.5816312 0.7893799 0.5498075 0.4241284 0.6544256 0.5444660
#> sample_2 0.5742356 0.6545343 0.7200251 0.4780816 0.4147944 0.4218850 0.4780816
#> sample_3 0.3812251 0.6275017 0.5338588 0.6618548 0.5279048 0.7515276 0.2661473
#> sample_4 0.3934781 0.5513866 0.5866482 0.5097039 0.4613281 0.8703654 0.3997117
#> sample_5 0.4682616 0.4152152 0.5260780 0.5375033 0.3913216 0.5883632 0.2373191
#> sample_6 0.2009778 0.5895577 0.6990641 0.1332119 0.4574601 0.3575289 0.5001367
#> gene794 gene795 gene796 gene797 gene798 gene799 gene800
#> sample_1 0.4574963 0.4519643 0.3330255 0.3959955 0.5498075 0.4016462 0.4297192
#> sample_2 0.5810004 0.6346374 0.6012140 0.3139343 0.5810004 0.6545343 0.5606654
#> sample_3 0.4737630 0.5634473 0.4615934 0.5575537 0.6732162 0.5693291 0.5634473
#> sample_4 0.3176206 0.6899532 0.4976847 0.5572931 0.7788153 0.5156951 0.6899532
#> sample_5 0.3611731 0.5545566 0.2118959 0.7090314 0.5883632 0.2999120 0.7304379
#> sample_6 0.2210074 0.6990641 0.5362313 0.5122174 0.5895577 0.3062635 0.5122174
#> gene801 gene802 gene803 gene804 gene805 gene806 gene807
#> sample_1 0.6130753 0.4016462 0.4630168 0.5337505 0.4016462 0.5121877 0.5974002
#> sample_2 0.4360218 0.4147944 0.1948620 0.5877517 0.4850410 0.7329726 0.8410720
#> sample_3 0.4858819 0.6043721 0.5869034 0.7515276 0.4919225 0.6788804 0.4919225
#> sample_4 0.6843087 0.4552245 0.1120394 0.5276407 0.2463139 0.6673096 0.6559217
#> sample_5 0.3429312 0.3853171 0.2812766 0.2875018 0.2118959 0.3184276 0.6982681
#> sample_6 0.3891228 0.4079179 0.5600511 0.5001367 0.5600511 0.6012782 0.4574601
#> gene808 gene809 gene810 gene811 gene812 gene813 gene814
#> sample_1 0.5604582 0.5763539 0.5657674 0.4849839 0.5337505 0.4464206 0.6026356
#> sample_2 0.3212391 0.3285281 0.4360218 0.6012140 0.6874380 0.5674573 0.7070279
#> sample_3 0.4979505 0.3114424 0.5693291 0.8545432 0.5985608 0.6504488 0.5810571
#> sample_4 0.3746973 0.3746973 0.4368370 0.5216740 0.5454682 0.4183332 0.5983082
#> sample_5 0.4448060 0.2118959 0.4857288 0.6766202 0.4565577 0.4915277 0.5939592
#> sample_6 0.5001367 0.4513126 0.5061833 0.7991838 0.4141564 0.4203817 0.6187719
#> gene815 gene816 gene817 gene818 gene819 gene820 gene821
#> sample_1 0.6850182 0.4849839 0.5974002 0.6799440 0.5551382 0.6646627 0.3846577
#> sample_2 0.6808828 0.6346374 0.7329726 0.8597952 0.6279791 0.5944895 0.2400063
#> sample_3 0.6504488 0.6958069 0.8224044 0.7953481 0.6101717 0.5338588 0.6618548
#> sample_4 0.7068216 0.4183332 0.7291628 0.6502111 0.5395378 0.4183332 0.4121392
#> sample_5 0.5088547 0.1733351 0.5715095 0.6438400 0.4857288 0.4506878 0.2562403
#> sample_6 0.6071210 0.5242488 0.8046476 0.9897650 0.6361625 0.4451524 0.3638748
#> gene822 gene823 gene824 gene825 gene827 gene828 gene829
#> sample_1 0.4740232 0.4297192 0.6389952 0.4958991 0.4016462 0.5498075 0.4129113
#> sample_2 0.7070279 0.7200251 0.6079251 0.3934330 0.6743149 0.5606654 0.6611407
#> sample_3 0.5398006 0.6618548 0.7349232 0.5398006 0.3050147 0.3874867 0.4858819
#> sample_4 0.3997117 0.6272567 0.6387565 0.5690705 0.3809709 0.4059320 0.5216740
#> sample_5 0.2812766 0.5602187 0.4330062 0.1473380 0.4152152 0.5375033 0.5030906
#> sample_6 0.5001367 0.1808111 0.5659761 0.6361625 0.6476994 0.3954012 0.4389792
#> gene830 gene831 gene832 gene833 gene835 gene836 gene837
#> sample_1 0.5121877 0.5283763 0.5229911 0.7649040 0.6234739 0.1901808 0.6182797
#> sample_2 0.4780816 0.3503016 0.5333607 0.5538598 0.5810004 0.5402075 0.6939806
#> sample_3 0.9745534 0.5457304 0.7570414 0.6788804 0.7515276 0.4247761 0.7460033
#> sample_4 0.4121392 0.7623579 0.6955868 0.5924840 0.6157117 0.3112095 0.5572931
#> sample_5 0.1990996 0.5658696 0.5883632 0.7569741 0.5602187 0.1990996 0.3913216
#> sample_6 0.5541142 0.6877268 0.4819223 0.6071210 0.5895577 0.4451524 0.3638748
#> gene838 gene839 gene840 gene841 gene842 gene843 gene844
#> sample_1 0.5391137 0.6799440 0.6697663 0.5391137 0.2566134 0.5816312 0.5974002
#> sample_2 0.6545343 0.6412827 0.4711078 0.3575285 0.4360218 0.6213076 0.3719360
#> sample_3 0.5575537 0.6217365 0.6275017 0.6618548 0.6217365 0.5634473 0.5927379
#> sample_4 0.6387565 0.6559217 0.4976847 0.9229103 0.4916566 0.6157117 0.5276407
#> sample_5 0.2999120 0.5375033 0.5030906 0.4448060 0.3551053 0.7884981 0.6874645
#> sample_6 0.3954012 0.6419366 0.6012782 0.4697166 0.5777905 0.5777905 0.4203817
#> gene845 gene846 gene847 gene848 gene849 gene850 gene851
#> sample_1 0.2921560 0.5551382 0.7649040 0.6234739 0.4685258 0.6026356 0.4795092
#> sample_2 0.5402075 0.7715206 0.6012140 0.3430593 0.6874380 0.6808828 0.1644280
#> sample_3 0.4185943 0.5927379 0.4798288 0.4432430 0.8116120 0.6389978 0.5398006
#> sample_4 0.6955868 0.4976847 0.5690705 0.3431255 0.7180135 0.7402697 0.5335953
#> sample_5 0.2436400 0.5431990 0.1733351 0.5431990 0.5260780 0.4565577 0.3122689
#> sample_6 0.6419366 0.7717122 0.6303770 0.4513126 0.5422043 0.4574601 0.3638748
#> gene852 gene853 gene854 gene855 gene856 gene857 gene858
#> sample_1 0.3388126 0.02616428 0.7052178 0.4795092 0.3560981 0.6697663 0.5604582
#> sample_2 0.6346374 0.07929561 0.5877517 0.2175094 0.4076889 0.4711078 0.5810004
#> sample_3 0.4493727 0.46159343 0.6043721 0.7126355 0.5398006 0.5634473 0.4554895
#> sample_4 0.2854237 0.00000000 0.3240177 0.6444894 0.5808007 0.7402697 0.5513866
#> sample_5 0.3973136 0.27503791 0.8196806 0.2246356 0.1473380 0.4799182 0.6051188
#> sample_6 0.3702071 0.50618326 0.9484657 0.6361625 0.7047164 0.4819223 0.6071210
#> gene859 gene861 gene862 gene863 gene864 gene865 gene866
#> sample_1 0.3675591 0.7550497 0.7202665 0.4464206 0.3959955 0.5391137 0.5763539
#> sample_2 0.7906313 0.6743149 0.6146230 0.8784154 0.3358015 0.5877517 0.6939806
#> sample_3 0.5634473 0.6561574 0.5099693 0.5219386 0.4371004 0.6217365 0.5516480
#> sample_4 0.4491082 0.6214899 0.5513866 0.6502111 0.3494672 0.5513866 0.5097039
#> sample_5 0.3245731 0.3913216 0.3672281 0.4389121 0.2937136 0.6217774 0.5260780
#> sample_6 0.4016662 0.9380498 0.6129522 0.8479967 0.4880063 0.5362313 0.4697166
#> gene867 gene868 gene869 gene870 gene871 gene872 gene873
#> sample_1 0.6130753 0.3903327 0.4958991 0.5551382 0.5391137 0.3618348 0.6286578
#> sample_2 0.8222447 0.7523014 0.2549216 0.5742356 0.4641197 0.3934330 0.5058340
#> sample_3 0.5927379 0.6561574 0.4737630 0.5219386 0.4185943 0.5575537 0.5159601
#> sample_4 0.7842806 0.4552245 0.6444894 0.6899532 0.6272567 0.7235934 0.6843087
#> sample_5 0.5488834 0.4270880 0.4506878 0.6051188 0.6820475 0.4389121 0.5771384
#> sample_6 0.5242488 0.6245802 0.6012782 0.6419366 0.5777905 0.5895577 0.3511693
#> gene874 gene875 gene876 gene877 gene878 gene879 gene880
#> sample_1 0.25661344 0.4574963 0.2980334 0.5013398 0.4904471 0.4072847 0.4904471
#> sample_2 0.71353269 0.9030841 0.5127366 0.4289608 0.8535656 0.5810004 0.9458266
#> sample_3 0.58105707 0.6101717 0.6901757 0.7844547 0.4858819 0.6332554 0.7460033
#> sample_4 0.67865327 0.6786533 0.2918915 0.6729869 0.6041209 0.6729869 0.6786533
#> sample_5 0.07461139 0.5088547 0.4624156 0.4270880 0.5317963 0.4448060 0.4152152
#> sample_6 0.52424881 0.6649206 0.5600511 0.4819223 0.6129522 0.5061833 0.6591914
#> gene881 gene882 gene883 gene884 gene885 gene886 gene887
#> sample_1 0.4685258 0.5067694 0.7152598 0.6492922 0.7001824 0.4685258 0.19628976
#> sample_2 0.7070279 0.6412827 0.6611407 0.5470406 0.7070279 0.6279791 0.35752845
#> sample_3 0.6958069 0.4979505 0.2856459 0.6561574 0.5457304 0.6275017 0.50396612
#> sample_4 0.7347215 0.6786533 0.7458074 0.4674190 0.6387565 0.3746973 0.26593412
#> sample_5 0.5203484 0.5602187 0.2999120 0.3913216 0.1668578 0.6982681 0.03415414
#> sample_6 0.3828311 0.5242488 0.5836800 0.8209783 0.3954012 0.6419366 0.41415642
#> gene888 gene889 gene890 gene891 gene892 gene893 gene894
#> sample_1 0.6595491 0.3675591 0.7401988 0.7649040 0.3330255 0.3903327 0.3789705
#> sample_2 0.6146230 0.4780816 0.8285321 0.5196253 0.5127366 0.5333607 0.4076889
#> sample_3 0.4979505 0.5751990 0.4493727 0.6159599 0.5279048 0.6332554 0.4247761
#> sample_4 0.5454682 0.4368370 0.7235934 0.8383796 0.2066744 0.4306821 0.3494672
#> sample_5 0.4740958 0.3429312 0.6051188 0.7569741 0.2937136 0.3973136 0.1473380
#> sample_6 0.4880063 0.4141564 0.3062635 0.5718892 0.5600511 0.3255926 0.4141564
#> gene895 gene896 gene897 gene898 gene899 gene900 gene901
#> sample_1 0.3846577 0.2566134 0.5763539 0.4795092 0.6492922 0.6182797 0.5337505
#> sample_2 0.4711078 0.7329726 0.3862825 0.5264999 0.7005105 0.5742356 0.3066137
#> sample_3 0.5099693 0.4123994 0.3370120 0.4858819 0.5810571 0.7404685 0.5634473
#> sample_4 0.4059320 0.2528686 0.5866482 0.4429790 0.7068216 0.6786533 0.5037005
#> sample_5 0.3245731 0.1342509 0.4565577 0.7884981 0.5995444 0.3611731 0.5771384
#> sample_6 0.4880063 0.6012782 0.7772270 0.5182393 0.5954238 0.4451524 0.6245802
#> gene902 gene903 gene904 gene905 gene906 gene907 gene908
#> sample_1 0.3388126 0.7302515 0.5763539 0.5498075 0.4241284 0.6697663 0.5175950
#> sample_2 0.6346374 0.6146230 0.7394278 0.9153514 0.7200251 0.9030841 0.6545343
#> sample_3 0.5516480 0.4493727 0.6561574 0.8863307 0.7735204 0.5099693 0.3560429
#> sample_4 0.4059320 0.7068216 0.6899532 0.7347215 0.3621094 0.5690705 0.4183332
#> sample_5 0.6493294 0.4032932 0.7410817 0.4973149 0.4032932 0.5488834 0.6548083
#> sample_6 0.4513126 0.6071210 0.6820418 0.6763458 0.7495490 0.5481653 0.4697166
#> gene909 gene910 gene911 gene912 gene913 gene914 gene915
#> sample_1 0.2685143 0.5337505 0.5710660 0.4849839 0.5229911 0.3503488 0.6748601
#> sample_2 0.4571170 0.3862825 0.7135327 0.1105011 0.8222447 0.5196253 0.7265050
#> sample_3 0.5398006 0.5219386 0.3560429 0.3812251 0.4798288 0.3306407 0.5099693
#> sample_4 0.3934781 0.4183332 0.6387565 0.4368370 0.6041209 0.6673096 0.7068216
#> sample_5 0.7569741 0.4211577 0.3429312 0.4448060 0.4973149 0.4330062 0.5260780
#> sample_6 0.2076694 0.3320076 0.6877268 0.3127206 0.6303770 0.3954012 0.4940778
#> gene917 gene918 gene919 gene920 gene921 gene922 gene923
#> sample_1 0.5391137 0.5868980 0.3272256 0.5229911 0.6441487 0.4574963 0.2625706
#> sample_2 0.5402075 0.6939806 0.4500999 0.4571170 0.6213076 0.1567765 0.6677342
#> sample_3 0.5751990 0.4554895 0.7460033 0.5039661 0.8062008 0.4858819 0.8170132
#> sample_4 0.7513346 0.4306821 0.5097039 0.4976847 0.2854237 0.5572931 0.4613281
#> sample_5 0.6273089 0.3490247 0.5715095 0.5317963 0.5602187 0.4915277 0.3245731
#> sample_6 0.7272179 0.7717122 0.5122174 0.4513126 0.3384087 0.5481653 0.7882259
#> gene924 gene925 gene926 gene927 gene928 gene929 gene930
#> sample_1 0.4795092 0.6951373 0.7649040 0.1220305 0.5868980 0.2685143 0.7893799
#> sample_2 0.6677342 0.4218850 0.4500999 0.3066137 0.4919862 0.3066137 0.7458707
#> sample_3 0.8968498 0.4615934 0.6618548 0.6958069 0.4309448 0.3749499 0.5985608
#> sample_4 0.5156951 0.4121392 0.6955868 0.4674190 0.6041209 0.3872312 0.8383796
#> sample_5 0.5939592 0.5488834 0.2875018 0.4857288 0.4506878 0.1342509 0.8658302
#> sample_6 0.6934009 0.2737638 0.4697166 0.4635947 0.5422043 0.3575289 0.8209783
#> gene931 gene932 gene933 gene934 gene935 gene936
#> sample_1 0.63899517 0.4129113 0.4016462 0.5604582 0.6595491 0.4519643
#> sample_2 0.08712398 0.3139343 0.4989172 0.8722200 0.7458707 0.4147944
#> sample_3 0.49795054 0.7404685 0.6275017 0.6901757 0.6845335 0.4676846
#> sample_4 0.55729314 0.6157117 0.4491082 0.4674190 0.5454682 0.4183332
#> sample_5 0.57713837 0.2687857 0.3429312 0.4330062 0.4857288 0.2812766
#> sample_6 0.53623130 0.8587351 0.8747697 0.6706387 0.7047164 0.5895577
#> gene937 gene938 gene939 gene940 gene941 gene942 gene943
#> sample_1 0.47950925 0.4129113 0.6850182 0.5498075 0.5337505 0.4849839 0.6646627
#> sample_2 0.13371785 0.7135327 0.6808828 0.7329726 0.8096347 0.5606654 0.7715206
#> sample_3 0.22013572 0.8545432 0.7625447 0.5457304 0.8757734 0.4858819 0.7404685
#> sample_4 0.43068206 0.4059320 0.6330122 0.7623579 0.4306821 0.7733398 0.6502111
#> sample_5 0.07461139 0.4506878 0.6657349 0.6657349 0.3793000 0.4799182 0.8300002
#> sample_6 0.62458018 0.6245802 0.5954238 0.3891228 0.7551054 0.4819223 0.5600511
#> gene944 gene945 gene946 gene947 gene948 gene949 gene950
#> sample_1 0.6130753 0.70018237 0.5013398 0.4849839 0.7747216 0.5444660 0.4185258
#> sample_2 0.9880361 0.45009990 0.6079251 0.6012140 0.5606654 0.4850410 0.4919862
#> sample_3 0.6332554 0.38122509 0.2068547 0.8062008 0.3999697 0.5751990 0.6675411
#> sample_4 0.6157117 0.07052561 0.4916566 0.5097039 0.8703654 0.6157117 0.6041209
#> sample_5 0.7090314 0.41521520 0.5995444 0.3672281 0.7727792 0.4857288 0.2499470
#> sample_6 0.4758258 0.24750365 0.6071210 0.3702071 0.6534510 0.8533708 0.7606514
#> gene951 gene952 gene953 gene954 gene955 gene956 gene957
#> sample_1 0.6492922 0.4297192 0.40728473 0.5763539 0.5498075 0.3503488 0.1779201
#> sample_2 0.4989172 0.4289608 0.45009990 0.2919249 0.2325239 0.5333607 0.6079251
#> sample_3 0.4432430 0.5751990 0.71822342 0.6675411 0.4919225 0.4061912 0.5634473
#> sample_4 0.6272567 0.5156951 0.82225463 0.5276407 0.4552245 0.4429790 0.4306821
#> sample_5 0.8861061 0.1342509 0.06790787 0.4092604 0.2373191 0.4448060 0.4799182
#> sample_6 0.5422043 0.3447959 0.45131263 0.2997922 0.4574601 0.4079179 0.4574601
#> gene958 gene960 gene961 gene962 gene963 gene964 gene965
#> sample_1 0.4685258 0.2685143 0.3959955 0.3272256 0.5121877 0.8709378 0.6441487
#> sample_2 0.4641197 0.5333607 0.5674573 0.3575285 0.4571170 0.4430682 0.3934330
#> sample_3 0.5927379 0.8331568 0.4371004 0.4676846 0.5634473 0.8224044 0.7844547
#> sample_4 0.5037005 0.2659341 0.3367701 0.2397445 0.4368370 0.6729869 0.7291628
#> sample_5 0.4973149 0.4915277 0.5715095 0.2875018 0.3732704 0.7357647 0.7832680
#> sample_6 0.4758258 0.4451524 0.3765259 0.3447959 0.5302461 0.7272179 0.6706387
#> gene967 gene968 gene969 gene970 gene971 gene972 gene973
#> sample_1 0.3732710 0.8850720 0.6026356 0.4849839 0.5391137 0.7451584 0.2803616
#> sample_2 0.5264999 0.7715206 0.5333607 0.7715206 0.3503016 0.5810004 0.6279791
#> sample_3 0.4309448 0.1733845 0.3686612 0.5338588 0.5279048 0.5751990 0.4554895
#> sample_4 0.5454682 0.6559217 0.4916566 0.3431255 0.6444894 0.3997117 0.6444894
#> sample_5 0.4565577 0.5488834 0.4506878 0.4799182 0.5771384 0.4915277 0.3853171
#> sample_6 0.6303770 0.6706387 0.8155448 0.6012782 0.7159886 0.2606630 0.3511693
#> gene974 gene975 gene976 gene977 gene978 gene979 gene980
#> sample_1 0.2625706 0.5868980 0.4740232 0.4740232 0.5229911 0.4958991 0.4185258
#> sample_2 0.6545343 0.4005685 0.5810004 0.3719360 0.6743149 0.4989172 0.8907722
#> sample_3 0.5398006 0.5985608 0.7014272 0.5398006 0.3874867 0.6732162 0.6217365
#> sample_4 0.3997117 0.4795629 0.5924840 0.5924840 0.6955868 0.7347215 0.5749415
#> sample_5 0.2499470 0.5260780 0.5030906 0.3853171 0.4032932 0.5545566 0.3913216
#> sample_6 0.4016662 0.7159886 0.4940778 0.7047164 0.7047164 0.5481653 0.5718892
#> gene981 gene982 gene983 gene984 gene985 gene986
#> sample_1 0.30389776 0.4129113 0.7893799 0.7001824 0.5283763 0.6646627
#> sample_2 0.58100040 0.6874380 0.1414215 0.4500999 0.4850410 0.6279791
#> sample_3 0.70142724 0.5457304 0.1258695 0.6732162 0.5810571 0.8598653
#> sample_4 0.47956288 0.3621094 0.4795629 0.7068216 0.3997117 0.7068216
#> sample_5 0.09462881 0.5488834 0.4740958 0.3973136 0.3122689 0.4973149
#> sample_6 0.48800631 0.4079179 0.6706387 0.5600511 0.4203817 0.6706387
#> gene987 gene988 gene989 gene990 gene992 gene993 gene994
#> sample_1 0.47402323 0.4464206 0.4904471 0.4904471 0.4072847 0.3560981 0.2625706
#> sample_2 0.40056845 0.5196253 0.6079251 0.7394278 0.4005685 0.3430593 0.4005685
#> sample_3 0.43710040 0.5457304 0.3749499 0.6159599 0.3937349 0.6901757 0.5751990
#> sample_4 0.63875645 0.2724451 0.6843087 0.6444894 0.4856160 0.3872312 0.4856160
#> sample_5 0.09462881 0.5375033 0.2499470 0.3793000 0.6051188 0.4032932 0.4152152
#> sample_6 0.68772681 0.7103579 0.6763458 0.7882259 0.4819223 0.5954238 0.3765259
#> gene995 gene996 gene997 gene998 gene999 gene1000
#> sample_1 0.5921543 0.5121877 0.6234739 0.5604582 0.3560981 0.2921560
#> sample_2 0.5674573 0.3647399 0.6012140 0.6743149 0.7779028 0.6012140
#> sample_3 0.6504488 0.6504488 0.5338588 0.4185943 0.4919225 0.7735204
#> sample_4 0.7124229 0.3304009 0.5216740 0.4856160 0.5395378 0.4976847
#> sample_5 0.4092604 0.4565577 0.3245731 0.2750379 0.5995444 0.3245731
#> sample_6 0.3320076 0.7159886 0.6990641 0.3765259 0.6649206 0.7882259
head(processed$test_x)
#> gene1 gene2 gene3 gene4 gene5 gene6 gene7
#> sample_1 0.5617003 0.4049174 0.6933897 0.1849977 0.4432761 0.6580266 0.1642078
#> sample_2 0.5416035 0.8122668 0.5086161 0.7079389 0.6576597 0.6386026 0.4416194
#> sample_3 0.5308172 0.7911148 0.6638675 0.6976011 0.5367299 0.7364704 0.4770565
#> sample_4 0.4879155 0.5190070 0.3152229 0.6347296 0.3430057 0.5497163 0.4511461
#> sample_5 0.6304019 0.8244588 0.5925057 0.5781394 0.3883284 0.5491468 0.5296225
#> sample_6 0.7231630 0.5898397 0.9763979 0.4148797 0.2589181 0.5678873 0.5401951
#> gene8 gene10 gene11 gene12 gene13 gene14 gene15
#> sample_1 0.6580266 0.5494459 0.3530213 0.1151475 0.3267431 0.3920247 0.5371428
#> sample_2 0.7016964 0.5218513 0.9656163 0.4144290 0.2678225 0.4212480 0.3314655
#> sample_3 0.8553653 0.3789658 0.7802674 0.6125244 0.5130068 0.6125244 0.6297394
#> sample_4 0.6978418 0.6100247 0.3922491 0.3319296 0.4511461 0.4084501 0.6100247
#> sample_5 0.8374311 0.3304679 0.6444605 0.3251382 0.5099385 0.5588499 0.6444605
#> sample_6 0.5733921 0.6278345 0.4896264 0.3017963 0.4725588 0.6812072 0.3855743
#> gene16 gene17 gene18 gene19 gene20 gene21 gene22
#> sample_1 0.6875238 0.5185959 0.4432761 0.3068870 0.5860645 0.2935785 0.6875238
#> sample_2 0.7079389 0.4212480 0.4348431 0.3174300 0.4752904 0.5547053 0.6194330
#> sample_3 0.5602617 0.5308172 0.6240123 0.3664693 0.5485195 0.5836052 0.9026414
#> sample_4 0.8240363 0.3096290 0.3922491 0.3922491 0.5950835 0.5850729 0.4617070
#> sample_5 0.8759336 0.4295517 0.4900922 0.3883284 0.6537874 0.6907380 0.4448302
#> sample_6 0.3973344 0.6706162 0.6599838 0.7387309 0.5678873 0.4090439 0.7283622
#> gene23 gene24 gene25 gene26 gene27 gene28 gene29
#> sample_1 0.5799914 0.7167425 0.23297131 0.5617003 0.5799914 0.6639486 0.1918968
#> sample_2 0.5350328 0.3593561 0.49532685 0.5218513 0.3384606 0.8483029 0.2319190
#> sample_3 0.7856961 0.6582071 0.44675589 0.8922016 0.3286555 0.5719568 0.4222868
#> sample_4 0.7026312 0.6000739 0.05020575 0.7873054 0.3540329 0.5699813 0.4458488
#> sample_5 0.6584374 0.6769479 0.14803901 0.6677105 0.3357858 0.2874961 0.5296225
#> sample_6 0.6007497 0.6970167 0.38557431 0.5065875 0.7747126 0.4207030 0.1838004
#> gene30 gene31 gene32 gene33 gene34 gene35 gene36
#> sample_1 0.6816468 0.8809764 0.4432761 0.7743649 0.2465425 0.7456878 0.4936924
#> sample_2 0.6639873 0.7635883 0.2678225 0.4075957 0.4212480 0.4348431 0.7819283
#> sample_3 0.8606561 0.5777868 0.2319198 0.6354552 0.6067634 0.3851940 0.7419811
#> sample_4 0.7216973 0.4826958 0.6543192 0.4191927 0.6978418 0.4511461 0.6930432
#> sample_5 0.6815534 0.5491468 0.4499016 0.5636868 0.3935201 0.5049923 0.7939153
#> sample_6 0.5346226 0.9382028 0.1901402 0.4725588 0.9525889 0.4438723 0.4207030
#> gene37 gene38 gene39 gene40 gene41 gene42 gene43
#> sample_1 0.4685870 0.5739064 0.2397644 0.4113436 0.7225532 0.2533059 0.6698593
#> sample_2 0.2463280 0.5742593 0.6703026 0.4685841 0.6513197 0.5218513 0.2891756
#> sample_3 0.4649740 0.6638675 0.3976107 0.4649740 0.4099748 0.3851940 0.5070457
#> sample_4 0.3485254 0.7359020 0.5950835 0.6050542 0.1236714 0.5138519 0.7733909
#> sample_5 0.5296225 0.5000358 0.6444605 0.3144432 0.1191508 0.3410920 0.7271297
#> sample_6 0.5234433 0.4438723 0.4380985 0.4265139 0.5065875 0.5234433 0.1582924
#> gene44 gene45 gene46 gene47 gene48 gene49 gene50
#> sample_1 0.8365342 0.5061692 0.6401924 0.5739064 0.7456878 0.2802124 0.2802124
#> sample_2 0.4212480 0.6513197 0.3244553 0.8001653 0.6766057 0.6194330 0.6891752
#> sample_3 0.5070457 0.6009911 0.4710215 0.6582071 0.8500647 0.2967653 0.6638675
#> sample_4 0.3595283 0.5497163 0.6737562 0.8376723 0.6978418 0.7026312 0.8602348
#> sample_5 0.3569407 0.7226107 0.4038700 0.6907380 0.4851049 0.3726857 0.7451212
#> sample_6 0.7075054 0.2278711 0.3855743 0.5678873 0.4380985 0.2465419 0.3619002
#> gene51 gene52 gene53 gene54 gene55 gene56 gene57
#> sample_1 0.4559574 0.3725845 0.6222547 0.4748825 0.7743649 0.3595561 0.5185959
#> sample_2 0.4886618 0.3732121 0.4685841 0.5416035 0.8062217 0.4075957 0.4007481
#> sample_3 0.5130068 0.3789658 0.6067634 0.7254176 0.9696047 0.4345470 0.2450047
#> sample_4 0.3263731 0.2644214 0.4774651 0.4826958 0.6930432 0.4564321 0.1832841
#> sample_5 0.4801073 0.3463865 0.2929097 0.5099385 0.8631677 0.4397482 0.3037006
#> sample_6 0.4839491 0.5234433 0.5568443 0.5898397 0.7387309 0.1774458 0.3017963
#> gene58 gene59 gene60 gene61 gene62 gene63 gene64
#> sample_1 0.6282455 0.4241562 0.5860645 0.7571905 0.3920247 0.6639486 0.4305426
#> sample_2 0.3384606 0.6194330 0.4752904 0.5807513 0.5677544 0.2535087 0.4618639
#> sample_3 0.2903452 0.5070457 0.4284233 0.4406578 0.4770565 0.3664693 0.5661151
#> sample_4 0.6050542 0.5750220 0.2587125 0.4983224 0.3040226 0.4352205 0.5190070
#> sample_5 0.5877265 0.7090026 0.4141756 0.3987006 0.5972755 0.6815534 0.6584374
#> sample_6 0.6007497 0.6812072 0.5122177 0.4148797 0.7899887 0.5513059 0.5898397
#> gene65 gene66 gene68 gene69 gene70 gene71 gene72
#> sample_1 0.6816468 0.3399101 0.5739064 0.4241562 0.8084302 0.4113436 0.1222039
#> sample_2 0.7141694 0.7574519 0.6828965 0.4483816 0.4007481 0.6130180 0.2174458
#> sample_3 0.5602617 0.3602009 0.5010725 0.5426306 0.4770565 0.5485195 0.4890892
#> sample_4 0.5547980 0.5344088 0.5241515 0.9914901 0.3868253 0.4617070 0.5138519
#> sample_5 0.7629792 0.5148746 0.3883284 0.7361422 0.4346554 0.4141756 0.3726857
#> sample_6 0.8001252 0.6224391 0.5788857 0.5065875 0.6007497 0.2835028 0.6170329
#> gene73 gene74 gene75 gene76 gene77 gene78 gene79
#> sample_1 0.4999371 0.6401924 0.5309728 0.6461485 0.5061692 0.5371428 0.2600545
#> sample_2 0.5218513 0.6258355 0.7016964 0.5481610 0.9074890 0.3244553 0.4685841
#> sample_3 0.4770565 0.6976011 0.7748286 0.5777868 0.6807831 0.4467559 0.6297394
#> sample_4 0.6396414 0.6149853 0.8149041 0.3704829 0.8376723 0.3430057 0.4774651
#> sample_5 0.3463865 0.8244588 0.6491285 0.5000358 0.3622005 0.4244373 0.4801073
#> sample_6 0.7127346 0.6061883 0.5122177 0.5788857 0.6061883 0.3796751 0.2957122
#> gene80 gene81 gene82 gene83 gene84 gene85 gene86
#> sample_1 0.6757587 0.4177565 0.1502697 0.3333336 0.3790781 0.6401924 0.5739064
#> sample_2 0.4618639 0.6065902 0.2820735 0.7203880 0.4483816 0.5547053 0.7513039
#> sample_3 0.6807831 0.6125244 0.6525358 0.4345470 0.5485195 0.5719568 0.4161373
#> sample_4 0.5035097 0.7453271 0.4669707 0.3704829 0.5699813 0.6248770 0.5950835
#> sample_5 0.6350972 0.4090283 0.5148746 0.2271282 0.5877265 0.5733315 0.4141756
#> sample_6 0.4265139 0.7127346 0.8152594 0.5401951 0.4725588 0.6116160 0.5678873
#> gene87 gene88 gene89 gene91 gene92 gene93 gene94
#> sample_1 0.6520933 0.5061692 0.6042125 0.5061692 0.6102383 0.3920247 0.1432771
#> sample_2 0.1662758 0.4953268 0.5350328 0.5936965 0.5936965 0.2962623 0.4144290
#> sample_3 0.4830791 0.6695169 0.3349919 0.7856961 0.7584511 0.4890892 0.5485195
#> sample_4 0.6494362 0.4084501 0.5446242 0.6347296 0.8103254 0.4983224 0.5035097
#> sample_5 0.5733315 0.7406359 0.2492558 0.8844067 0.6630784 0.2874961 0.3935201
#> sample_6 0.5178363 0.4090439 0.6759169 0.1325426 0.5953001 0.6224391 0.5788857
#> gene95 gene96 gene97 gene98 gene99 gene100 gene101
#> sample_1 0.5185959 0.5433004 0.6342247 0.5860645 0.6520933 0.6162523 0.8027786
#> sample_2 0.2029079 0.6386026 0.5872303 0.6194330 0.7016964 0.1736354 0.4144290
#> sample_3 0.6125244 0.4161373 0.7254176 0.4161373 0.5661151 0.4710215 0.3539191
#> sample_4 0.5750220 0.7121824 0.5649304 0.5086861 0.6000739 0.6298082 0.7026312
#> sample_5 0.4141756 0.5148746 0.6067868 0.0000000 0.3674488 0.5540032 0.4700808
#> sample_6 0.6116160 0.3678381 0.7127346 0.4265139 0.6917571 0.4611206 0.6864872
#> gene102 gene103 gene104 gene105 gene106 gene107 gene108
#> sample_1 0.36607712 0.6282455 0.7050881 0.4936924 0.4496233 0.5061692 0.0000000
#> sample_2 0.61943304 0.2820735 0.6828965 0.1956144 0.3524058 0.4212480 0.3103894
#> sample_3 0.67515545 0.3539191 0.4099748 0.4770565 0.4345470 0.5189557 0.5308172
#> sample_4 0.55479795 0.3704829 0.5446242 0.5035097 0.5497163 0.5800525 0.3868253
#> sample_5 0.64446047 0.3779112 0.3569407 0.4600123 0.4549623 0.6397834 0.4448302
#> sample_6 0.03374682 0.6706162 0.6061883 0.3973344 0.6278345 0.4496339 0.3855743
#> gene109 gene110 gene111 gene112 gene113 gene114 gene115
#> sample_1 0.5555792 0.3464726 0.3725845 0.4874351 0.3201386 0.6875238 0.2735077
#> sample_2 0.6449674 0.4752904 0.6954418 0.5677544 0.3662914 0.7389728 0.5416035
#> sample_3 0.6468533 0.3539191 0.7254176 0.4345470 0.6525358 0.7911148 0.6009911
#> sample_4 0.4931244 0.3704829 0.3868253 0.4669707 0.3813897 0.7264412 0.3152229
#> sample_5 0.6304019 0.6907380 0.3144432 0.6953171 0.3410920 0.6115284 0.5540032
#> sample_6 0.5234433 0.3380180 0.6546519 0.6970167 0.6812072 0.6116160 0.6170329
#> gene116 gene117 gene118 gene119 gene120 gene121 gene122
#> sample_1 0.4811652 0.4432761 0.4748825 0.5061692 0.5555792 0.4685870 0.5739064
#> sample_2 0.4819830 0.5416035 0.1292261 0.1736354 0.4953268 0.5416035 0.3314655
#> sample_3 0.7364704 0.5543965 0.4830791 0.5189557 0.6067634 0.4467559 0.4770565
#> sample_4 0.6543192 0.5497163 0.3430057 0.6396414 0.6149853 0.5292855 0.5497163
#> sample_5 0.4750993 0.4851049 0.4244373 0.7718587 0.6209836 0.5442806 0.2326792
#> sample_6 0.5178363 0.4031955 0.8601627 0.3499854 0.6812072 0.7022661 0.5457562
#> gene123 gene124 gene125 gene126 gene127 gene128 gene129
#> sample_1 0.7514445 0.4622786 0.4622786 0.6698593 0.4369159 0.6816468 0.5799914
#> sample_2 0.5807513 0.5086161 0.4685841 0.3732121 0.2678225 0.4685841 0.5152405
#> sample_3 0.5070457 0.3727242 0.4284233 0.7143228 0.5189557 0.6354552 0.3789658
#> sample_4 0.6737562 0.5344088 0.4983224 0.5138519 0.5547980 0.8422011 0.6978418
#> sample_5 0.5198006 0.3569407 0.6304019 0.6256974 0.5345185 1.0000000 0.6907380
#> sample_6 0.5346226 0.3199675 0.6599838 0.6061883 0.5346226 0.6759169 0.4896264
#> gene130 gene131 gene132 gene133 gene134 gene135 gene136
#> sample_1 0.4369159 0.6933897 0.3333336 0.5617003 0.7514445 0.4685870 0.5123888
#> sample_2 0.7016964 0.5742593 0.2678225 0.5742593 0.4007481 0.5350328 0.6703026
#> sample_3 0.5070457 0.2121818 0.8659375 0.4770565 0.7802674 0.7254176 0.4099748
#> sample_4 0.6248770 0.4983224 0.5750220 0.6494362 0.4669707 0.5241515 0.6543192
#> sample_5 0.4950691 0.3987006 0.6861501 0.5099385 0.3674488 0.7090026 0.6020359
#> sample_6 0.6332192 0.7231630 0.6061883 0.5788857 0.6970167 0.5457562 0.6546519
#> gene137 gene138 gene140 gene141 gene142 gene143 gene144
#> sample_1 0.4748825 0.5494459 0.2802124 0.4811652 0.39847776 0.5860645 0.6342247
#> sample_2 0.4953268 0.5350328 0.3314655 0.7697131 0.08420143 0.5152405 0.6449674
#> sample_3 0.7639205 0.1923094 0.4649740 0.5426306 0.65253576 0.6297394 0.6240123
#> sample_4 0.4931244 0.3263731 0.4826958 0.5649304 0.61993600 0.7121824 0.7687354
#> sample_5 0.9959659 0.4141756 0.7585271 0.6584374 0.52962252 0.4700808 0.4193119
#> sample_6 0.4323124 0.3619002 0.4323124 0.6170329 0.48962642 0.4725588 0.6116160
#> gene145 gene146 gene148 gene149 gene150 gene151 gene152
#> sample_1 0.3464726 0.3135199 0.5860645 0.5617003 0.1432771 0.3855582 0.3333336
#> sample_2 0.4685841 0.5416035 0.6386026 0.6065902 0.4348431 0.2749558 0.6513197
#> sample_3 0.7364704 0.4589139 0.4649740 0.4284233 0.4890892 0.4950870 0.2967653
#> sample_4 0.8422011 0.6543192 0.5598693 0.6100247 0.5292855 0.7733909 0.4138272
#> sample_5 0.8844067 0.5296225 0.4549623 0.2929097 0.4600123 0.6630784 0.4141756
#> sample_6 0.7075054 0.8202855 0.4725588 0.5513059 0.4952919 0.6864872 0.3320145
#> gene153 gene155 gene156 gene157 gene158 gene159 gene160
#> sample_1 0.2667884 0.3530213 0.3068870 0.4432761 0.4622786 0.4559574 0.3267431
#> sample_2 0.5872303 0.5677544 0.2820735 0.7141694 0.3662914 0.7635883 0.1366699
#> sample_3 0.4467559 0.5010725 0.4950870 0.4649740 0.0000000 0.6067634 0.3789658
#> sample_4 0.7359020 0.6978418 0.4352205 0.5750220 0.4511461 0.4564321 0.5497163
#> sample_5 0.5540032 0.7540668 0.4900922 0.5925057 0.2657190 0.5540032 0.2271282
#> sample_6 0.4031955 0.6224391 0.3380180 0.3259977 0.3973344 0.4090439 0.3320145
#> gene161 gene162 gene163 gene164 gene165 gene167 gene168
#> sample_1 0.2802124 0.3660771 0.7341421 0.5494459 0.4936924 0.6698593 0.3984778
#> sample_2 0.3454407 0.3662914 0.6001497 0.5612364 0.5742593 0.6891752 0.5019783
#> sample_3 0.2450047 0.5602617 0.6807831 0.6582071 0.5426306 0.6525358 0.5248924
#> sample_4 0.4669707 0.3540329 0.4564321 0.4458488 0.4458488 0.7074114 0.7406190
#> sample_5 0.4141756 0.6861501 0.6723336 0.6444605 0.4090283 0.6491285 0.8114162
#> sample_6 0.6007497 0.3678381 0.7542100 0.3078669 0.7542100 0.5568443 0.6653052
#> gene169 gene170 gene171 gene172 gene173 gene174 gene175
#> sample_1 0.6102383 0.5799914 0.8365342 0.32674312 0.6461485 0.6222547 0.3660771
#> sample_2 0.3938859 0.5218513 0.4075957 0.03854408 0.4075957 0.3524058 0.2962623
#> sample_3 0.5485195 0.3413146 0.7584511 0.58360519 0.5248924 0.4710215 0.6297394
#> sample_4 0.7780377 0.3430057 0.7311761 0.21838045 0.5086861 0.3759423 0.7311761
#> sample_5 0.4700808 0.4090283 0.7361422 0.49506913 0.3304679 0.6584374 0.5636868
#> sample_6 0.5678873 0.3499854 0.5843682 0.61161601 0.5009455 0.3440083 0.6116160
#> gene176 gene177 gene178 gene179 gene180 gene181 gene182
#> sample_1 0.4999371 0.5617003 0.5494459 0.6102383 0.3530213 0.7857617 0.6875238
#> sample_2 0.4752904 0.6891752 0.7389728 0.3870092 0.3033335 0.4212480 0.3662914
#> sample_3 0.6240123 0.4950870 0.6297394 0.6009911 0.6920059 0.4222868 0.8126892
#> sample_4 0.6882354 0.4138272 0.7500264 0.4458488 0.5850729 0.2587125 0.5950835
#> sample_5 0.5685140 0.3987006 0.5198006 0.4851049 0.7044494 0.6350972 0.7983025
#> sample_6 0.7439004 0.5678873 0.7231630 0.5623714 0.5843682 0.6332192 0.4380985
#> gene183 gene184 gene185 gene186 gene187 gene188 gene189
#> sample_1 0.3920247 0.5555792 0.5981750 0.2667884 0.4496233 0.4874351 0.3725845
#> sample_2 0.5677544 0.4144290 0.4075957 0.5350328 0.0917490 0.6576597 0.5677544
#> sample_3 0.4345470 0.1182635 0.6920059 0.4890892 0.4284233 0.4890892 0.4710215
#> sample_4 0.3595283 0.4245468 1.0000000 0.4983224 0.3374738 0.7687354 0.2067364
#> sample_5 0.4750993 0.3197966 0.8287907 0.3463865 0.4499016 0.5636868 0.4090283
#> sample_6 0.7179538 0.5678873 0.9043357 0.4380985 0.3259977 0.3499854 0.7022661
#> gene190 gene191 gene192 gene193 gene194 gene195 gene196
#> sample_1 0.4559574 0.4049174 0.6102383 0.4622786 0.2465425 0.8197024 0.9302225
#> sample_2 0.4685841 0.2606734 0.4886618 0.5416035 0.3174300 0.7819283 0.4416194
#> sample_3 0.4770565 0.6354552 0.4890892 0.1723007 0.3159412 0.4890892 0.7639205
#> sample_4 0.4405403 0.2644214 0.5395217 0.4030614 0.2357454 0.5035097 0.5395217
#> sample_5 0.3831254 0.4295517 0.5099385 0.4090283 0.5148746 0.5540032 0.6256974
#> sample_6 0.5290387 0.3678381 0.3796751 0.4148797 0.3199675 0.4839491 0.8651064
#> gene197 gene198 gene200 gene201 gene202 gene203 gene204
#> sample_1 0.4936924 0.7225532 0.5433004 0.5247905 0.6520933 0.6282455 0.4305426
#> sample_2 0.4212480 0.3103894 0.6001497 0.7389728 0.2535087 0.4075957 0.4348431
#> sample_3 0.2967653 0.4830791 0.4770565 0.7639205 0.4528412 0.6807831 0.3851940
#> sample_4 0.2814703 0.4458488 0.3813897 0.7593984 0.6248770 0.6298082 0.5900832
#> sample_5 0.3516694 0.5148746 0.4346554 0.7406359 0.5685140 0.4750993 0.6397834
#> sample_6 0.3440083 0.7127346 0.6116160 0.5623714 0.5623714 0.6439567 0.5122177
#> gene205 gene206 gene207 gene208 gene209 gene210 gene211
#> sample_1 0.5185959 0.3201386 0.5981750 0.4936924 0.6102383 0.4241562 0.3530213
#> sample_2 0.5612364 0.4075957 0.5807513 0.8243233 0.8001653 0.3244553 0.5218513
#> sample_3 0.5248924 0.5836052 0.7748286 0.4830791 0.8869676 0.6125244 0.6695169
#> sample_4 0.6248770 0.5547980 0.8376723 0.5395217 0.7264412 0.4245468 0.4298893
#> sample_5 0.5491468 0.7540668 0.6677105 0.6020359 0.6815534 0.7674231 0.3831254
#> sample_6 0.8303098 0.4668457 0.6706162 0.6061883 0.5843682 0.4090439 0.5788857
#> gene212 gene213 gene214 gene215 gene216 gene217 gene218
#> sample_1 0.5309728 0.6162523 0.6933897 0.6875238 0.7399204 0.65209328 0.4874351
#> sample_2 0.4752904 0.3103894 0.4886618 0.6065902 0.6322253 0.34544072 0.3384606
#> sample_3 0.2319198 0.4770565 0.4467559 0.6582071 0.3664693 0.09086489 0.3159412
#> sample_4 0.5241515 0.5086861 0.3374738 0.4191927 0.7593984 0.46697074 0.2587125
#> sample_5 0.5394045 0.5099385 0.3674488 0.5247166 0.5394045 0.54428056 0.3037006
#> sample_6 0.6170329 0.3914607 0.6653052 0.4323124 0.5733921 0.58436819 0.3259977
#> gene219 gene221 gene222 gene223 gene224 gene225 gene226
#> sample_1 0.5247905 0.5739064 0.5061692 0.3399101 0.4622786 0.6042125 0.3201386
#> sample_2 0.5677544 0.4953268 0.6194330 0.6258355 0.3174300 0.4886618 0.4144290
#> sample_3 0.6125244 0.5308172 0.8073105 0.5426306 0.4222868 0.8234168 0.4710215
#> sample_4 0.6978418 0.6640566 0.4931244 0.7965389 0.3208042 0.7169444 0.6591926
#> sample_5 0.7044494 0.6067868 0.6677105 0.8546194 0.3410920 0.6537874 0.8631677
#> sample_6 0.7022661 0.3499854 0.6706162 0.3973344 0.3737631 0.4611206 0.4090439
#> gene227 gene228 gene229 gene230 gene231 gene232 gene233
#> sample_1 0.4369159 0.4811652 0.6042125 0.5371428 0.5739064 0.5185959 0.5555792
#> sample_2 0.4953268 0.3314655 0.3384606 0.7635883 0.6828965 0.4953268 0.6513197
#> sample_3 0.4284233 0.6638675 0.4037993 0.4890892 0.6067634 0.4284233 0.5719568
#> sample_4 0.5138519 0.4617070 0.5241515 0.7121824 0.5395217 0.4191927 0.7873054
#> sample_5 0.2159877 0.2326792 0.5588499 0.8201191 0.6584374 0.5000358 0.5972755
#> sample_6 0.3559493 0.8552099 0.5843682 0.2090712 0.4668457 0.6599838 0.6061883
#> gene234 gene235 gene236 gene237 gene238 gene239 gene240
#> sample_1 0.8140714 0.3790781 0.5371428 0.2397644 0.2193403 0.4113436 0.4874351
#> sample_2 0.7574519 0.6322253 0.3524058 0.5350328 0.4212480 0.5807513 0.4752904
#> sample_3 0.6125244 0.5602617 0.5308172 0.4649740 0.6240123 0.6411598 0.2645227
#> sample_4 0.4191927 0.3813897 0.7359020 0.5241515 0.7359020 0.4352205 0.4879155
#> sample_5 0.6815534 0.6256974 0.8026817 0.5099385 0.6256974 0.4448302 0.4141756
#> sample_6 0.6970167 0.4896264 0.3796751 0.6864872 0.4265139 0.4952919 0.6170329
#> gene241 gene242 gene243 gene244 gene245 gene246 gene247
#> sample_1 0.7914444 0.3790781 0.6875238 0.3135199 0.2869027 0.5860645 0.4432761
#> sample_2 0.4551297 0.6639873 0.4144290 0.5218513 0.3033335 0.5612364 0.7203880
#> sample_3 0.4284233 0.8500647 0.5189557 0.6067634 0.2515252 0.6525358 0.5602617
#> sample_4 0.4511461 0.5497163 0.4774651 0.5241515 0.6149853 0.7687354 0.5241515
#> sample_5 0.4851049 0.6584374 0.3037006 0.3726857 0.4900922 0.6067868 0.6677105
#> sample_6 0.7644807 0.3914607 0.3078669 0.3499854 0.5065875 0.5898397 0.8353081
#> gene248 gene249 gene250 gene251 gene252 gene253 gene254
#> sample_1 0.4432761 0.6401924 0.6580266 0.4559574 0.5061692 0.4559574 0.4811652
#> sample_2 0.1956144 0.6449674 0.6194330 0.6576597 0.7574519 0.6576597 0.3244553
#> sample_3 0.5836052 0.4649740 0.6525358 0.4950870 0.6976011 0.5308172 0.3602009
#> sample_4 0.3759423 0.5497163 0.3595283 0.3704829 0.8331352 0.3813897 0.3595283
#> sample_5 0.5636868 0.3622005 0.3987006 0.2983112 0.6998876 0.6537874 0.5972755
#> sample_6 0.7593502 0.1260668 0.7335515 0.3973344 0.5346226 0.5065875 0.5346226
#> gene255 gene256 gene257 gene258 gene259 gene260 gene261
#> sample_1 0.7109208 0.4685870 0.1502697 0.1711533 0.2869027 0.6816468 0.6520933
#> sample_2 0.4886618 0.7635883 0.4953268 0.4685841 0.5742593 0.4075957 0.4348431
#> sample_3 0.5485195 0.5189557 0.2515252 0.5894120 0.4528412 0.7639205 0.6751555
#> sample_4 0.6298082 0.4352205 0.2125652 0.7780377 0.3922491 0.8870434 0.7547168
#> sample_5 0.4549623 0.6209836 0.2492558 0.5345185 0.3987006 0.7585271 0.7226107
#> sample_6 0.5953001 0.6706162 0.5843682 0.5898397 0.6546519 0.6493096 0.5290387
#> gene262 gene263 gene264 gene265 gene266 gene267 gene268
#> sample_1 0.6933897 0.4811652 0.4369159 0.5371428 0.5185959 0.3201386 0.4748825
#> sample_2 0.5284487 0.7016964 0.5284487 0.4752904 0.4752904 0.5936965 1.0000000
#> sample_3 0.5426306 0.5367299 0.7639205 0.7198755 0.6807831 0.7584511 0.7087596
#> sample_4 0.4564321 0.4458488 0.5190070 0.4931244 0.5850729 0.7640713 0.5750220
#> sample_5 0.4750993 0.3569407 0.4801073 0.3831254 0.3831254 0.4193119 0.8759336
#> sample_6 0.7542100 0.6332192 0.6278345 0.6917571 0.4896264 0.7179538 0.4090439
#> gene269 gene270 gene271 gene272 gene273 gene274 gene275
#> sample_1 0.4748825 0.4559574 0.4177565 0.5617003 0.6698593 0.5309728 0.5799914
#> sample_2 0.4212480 0.7451442 0.6130180 0.3870092 0.4007481 0.3732121 0.4752904
#> sample_3 0.5485195 0.7419811 0.7254176 0.5010725 0.4099748 0.3413146 0.2774625
#> sample_4 0.5035097 0.6689111 0.3650116 0.2183804 0.8103254 0.4298893 0.3374738
#> sample_5 0.4397482 0.6861501 0.3987006 0.1074978 0.5148746 0.4038700 0.2271282
#> sample_6 0.3017963 0.6759169 0.6706162 0.6332192 0.8896910 0.3320145 0.4668457
#> gene276 gene277 gene278 gene279 gene280 gene281 gene282
#> sample_1 0.5981750 0.5617003 0.54944590 0.4241562 0.5494459 0.3464726 0.5678094
#> sample_2 0.8243233 0.3524058 0.09927908 0.6703026 0.7389728 0.2891756 0.5872303
#> sample_3 0.9440311 0.4099748 0.39761073 0.4890892 0.6807831 0.3602009 0.5719568
#> sample_4 0.7026312 0.4722234 0.52415153 0.4138272 0.6494362 0.5649304 0.7074114
#> sample_5 0.5394045 0.5540032 0.66307840 0.5442806 0.6677105 0.3831254 0.5442806
#> sample_6 0.6224391 0.3855743 0.64930956 0.5346226 0.6812072 0.7747126 0.7644807
#> gene283 gene284 gene285 gene286 gene287 gene288 gene289
#> sample_1 0.3984778 1.0000000 0.34647262 0.2465425 0.6102383 0.4496233 0.6102383
#> sample_2 0.3174300 0.6766057 0.41442903 0.3938859 0.6954418 0.6891752 0.4416194
#> sample_3 0.7031857 0.7254176 0.69760114 0.6297394 0.7364704 0.7748286 0.6863999
#> sample_4 0.5395217 0.8240363 0.63472964 0.5547980 0.6882354 0.7733909 0.6000739
#> sample_5 0.5829377 0.7361422 0.08402094 0.6067868 0.5491468 0.5925057 0.2766322
#> sample_6 0.5953001 0.9237400 0.48962642 0.3199675 0.3973344 0.5898397 0.6385932
#> gene290 gene291 gene292 gene293 gene294 gene295 gene296
#> sample_1 0.5494459 0.3790781 0.4999371 0.2397644 0.1642078 0.4049174 0.3399101
#> sample_2 0.7574519 0.4953268 0.3801180 0.6513197 0.4007481 0.2678225 0.4953268
#> sample_3 0.6695169 0.5308172 0.5010725 0.5010725 0.3349919 0.6297394 0.4037993
#> sample_4 0.3540329 0.3319296 0.5344088 0.4511461 0.4669707 0.4983224 0.4298893
#> sample_5 0.6162607 0.6630784 0.5247166 0.3622005 0.4346554 0.4499016 0.5877265
#> sample_6 0.2712383 0.4031955 0.3737631 0.3973344 0.6007497 0.4611206 0.5953001
#> gene297 gene298 gene299 gene300 gene301 gene302 gene303
#> sample_1 0.7167425 0.7971167 0.4241562 0.2465425 0.5247905 0.5860645 0.5433004
#> sample_2 0.4551297 0.6194330 0.6449674 0.4212480 0.3174300 0.6703026 0.2319190
#> sample_3 0.6182740 0.6525358 0.4222868 0.7584511 0.4406578 0.5602617 0.4950870
#> sample_4 0.7026312 0.6689111 0.6978418 0.7453271 0.1773864 0.4617070 0.9914901
#> sample_5 0.5636868 0.8588974 0.7585271 0.7044494 0.1594979 0.5148746 0.6907380
#> sample_6 0.5513059 0.5788857 0.5733921 0.6224391 0.5568443 0.6812072 0.4323124
#> gene304 gene305 gene306 gene308 gene309 gene310 gene311
#> sample_1 0.4999371 0.4432761 0.7050881 0.6162523 0.5617003 0.5185959 0.7743649
#> sample_2 0.6001497 0.6639873 0.4819830 0.2820735 0.6194330 0.3662914 0.7513039
#> sample_3 0.5130068 0.5130068 0.5952073 0.6125244 0.8447546 0.4467559 0.5367299
#> sample_4 0.7169444 0.5497163 0.4669707 0.5547980 0.7121824 0.6149853 0.6640566
#> sample_5 0.5049923 0.2820702 0.4801073 0.5636868 0.7495981 0.6350972 0.7983025
#> sample_6 0.6546519 0.5234433 0.6493096 0.5678873 0.5401951 0.6970167 0.4839491
#> gene312 gene313 gene314 gene315 gene316 gene317 gene319
#> sample_1 0.7167425 0.3725845 0.7456878 0.7341421 0.5555792 0.5494459 0.5799914
#> sample_2 0.5218513 0.4685841 0.6322253 0.4483816 0.4483816 0.5284487 0.7880187
#> sample_3 0.5661151 0.3914090 0.7802674 0.6468533 0.5777868 0.4830791 0.6920059
#> sample_4 0.6737562 0.6100247 0.7873054 0.5750220 0.5598693 0.4564321 0.5446242
#> sample_5 0.6256974 0.4801073 0.8674306 0.6209836 0.4346554 0.7135472 0.7180832
#> sample_6 0.4952919 0.4438723 0.5788857 0.5568443 0.7335515 0.4896264 0.6599838
#> gene320 gene321 gene322 gene324 gene325 gene326 gene327
#> sample_1 0.43691593 0.3267431 0.4369159 0.6401924 0.6401924 0.3333336 0.6222547
#> sample_2 0.07663628 0.2174458 0.5218513 0.4348431 0.2174458 0.3314655 0.6130180
#> sample_3 0.75297140 0.5719568 0.6807831 0.5661151 0.3851940 0.6240123 0.5308172
#> sample_4 0.47746509 0.5699813 0.7121824 0.4511461 0.6640566 0.3540329 0.7311761
#> sample_5 0.79391532 0.5198006 0.6020359 0.5972755 0.6256974 0.2874961 0.5877265
#> sample_6 0.50094554 0.6224391 0.5733921 0.9091998 0.6599838 0.1901402 0.3380180
#> gene328 gene329 gene330 gene331 gene332 gene333 gene334
#> sample_1 0.6933897 0.1987805 0.4936924 0.5185959 0.15026974 0.1918968 0.2465425
#> sample_2 0.5612364 0.2820735 0.7203880 0.4953268 0.13666991 0.6322253 0.5807513
#> sample_3 0.2384696 0.3914090 0.5010725 0.5070457 0.43454698 0.5367299 0.6297394
#> sample_4 0.2472554 0.2472554 0.7780377 0.4564321 0.62980816 0.4030614 0.6785920
#> sample_5 0.2929097 0.4549623 0.4851049 0.7271297 0.35694068 0.5000358 0.7762863
#> sample_6 0.5843682 0.3796751 0.4952919 0.6546519 0.08688464 0.6224391 0.5009455
#> gene335 gene336 gene337 gene338 gene339 gene340 gene341
#> sample_1 0.6816468 0.73414214 0.4113436 0.6401924 0.3790781 0.8699255 0.7686507
#> sample_2 0.4075957 0.50861614 0.2749558 0.5284487 0.6386026 0.5936965 0.6065902
#> sample_3 0.6411598 0.22535530 0.3095632 0.3976107 0.6525358 0.6354552 0.3602009
#> sample_4 0.4405403 0.68823543 0.5241515 0.2183804 0.5138519 0.6100247 0.3374738
#> sample_5 0.6444605 0.77628627 0.5491468 0.1016500 0.7495981 0.6723336 0.3144432
#> sample_6 0.6007497 0.04712904 0.6546519 0.7696015 0.7075054 0.8001252 0.7490601
#> gene342 gene343 gene344 gene345 gene346 gene347 gene349
#> sample_1 0.53097281 0.3267431 0.7399204 0.4811652 0.5617003 0.7109208 0.5123888
#> sample_2 0.44161938 0.4819830 0.7513039 0.5807513 0.6828965 0.7141694 0.3103894
#> sample_3 0.31594118 0.5189557 1.0000000 0.7309492 0.5070457 0.6920059 0.1789855
#> sample_4 0.32637312 0.4826958 0.6248770 0.4931244 0.4931244 0.6445436 0.3152229
#> sample_5 0.06626178 0.6491285 0.9221707 0.4141756 0.4801073 0.5685140 0.3883284
#> sample_6 0.60074966 0.5234433 0.6224391 0.4380985 0.5513059 0.3914607 0.7022661
#> gene350 gene351 gene352 gene353 gene354 gene355 gene356
#> sample_1 0.2329713 0.5309728 0.6520933 0.2802124 0.4999371 0.2600545 0.5555792
#> sample_2 0.5612364 0.5284487 0.6639873 0.6386026 0.4618639 0.6065902 0.4348431
#> sample_3 0.4284233 0.6354552 0.8073105 0.4528412 0.5130068 0.9130440 0.6751555
#> sample_4 0.8057384 0.6978418 0.9786706 0.6591926 0.5138519 0.8103254 0.4774651
#> sample_5 0.3987006 0.6769479 0.9221707 0.3357858 0.4448302 0.7271297 0.5829377
#> sample_6 0.6439567 0.4668457 0.4553833 0.6332192 0.7644807 0.4207030 0.5009455
#> gene357 gene360 gene361 gene362 gene363 gene364 gene365
#> sample_1 0.6698593 0.2261633 0.2802124 0.4748825 0.6992444 0.4177565 0.5061692
#> sample_2 0.7203880 0.4075957 0.3801180 0.4416194 0.5936965 0.4551297 0.3454407
#> sample_3 0.9078473 0.5777868 0.6751555 0.6525358 0.5719568 0.4710215 0.8180579
#> sample_4 0.7359020 0.4511461 0.5292855 0.5800525 0.5138519 0.6248770 0.6149853
#> sample_5 0.8759336 0.5049923 0.6630784 0.5049923 0.6067868 0.6256974 0.5148746
#> sample_6 0.6007497 0.6812072 0.7022661 0.7950617 0.4496339 0.4668457 0.7127346
#> gene366 gene367 gene368 gene369 gene370 gene371 gene372
#> sample_1 0.6162523 0.4748825 0.7686507 0.4811652 0.7857617 0.8084302 0.5185959
#> sample_2 0.3593561 0.3524058 0.6130180 0.4886618 0.6449674 0.7697131 0.2891756
#> sample_3 0.6976011 0.6411598 0.6468533 0.5485195 0.6240123 0.5010725 0.4528412
#> sample_4 0.6248770 0.4245468 0.5292855 0.6050542 0.6396414 0.7873054 0.6347296
#> sample_5 0.6998876 0.6998876 0.4750993 0.5877265 0.2602437 0.7226107 0.4244373
#> sample_6 0.6116160 0.5843682 0.7490601 0.4725588 0.7644807 0.5178363 0.5733921
#> gene373 gene374 gene375 gene376 gene377 gene378 gene379
#> sample_1 0.3530213 0.6757587 0.4748825 0.3984778 0.5247905 0.7167425 0.4999371
#> sample_2 0.2463280 0.2891756 0.5612364 0.5612364 0.8243233 0.2029079 0.5481610
#> sample_3 0.6182740 0.4037993 0.3789658 0.6695169 0.4890892 0.5661151 0.4528412
#> sample_4 0.3208042 0.5344088 0.3152229 0.5086861 0.8422011 0.6000739 0.4352205
#> sample_5 0.6444605 0.3935201 0.3779112 0.5491468 0.5247166 0.6067868 0.4750993
#> sample_6 0.3855743 0.7950617 0.4090439 0.3855743 0.6599838 0.6061883 0.6917571
#> gene380 gene382 gene383 gene384 gene385 gene386 gene387
#> sample_1 0.6520933 0.3855582 0.3399101 0.5433004 0.4369159 0.3464726 0.6401924
#> sample_2 0.7389728 0.5481610 0.6703026 0.6828965 0.3314655 0.7141694 0.5086161
#> sample_3 0.3914090 0.4830791 0.3789658 0.5485195 0.4710215 0.5426306 0.8180579
#> sample_4 0.4405403 0.6640566 0.3319296 0.4983224 0.5699813 0.6785920 0.3976611
#> sample_5 0.4141756 0.3935201 0.5442806 0.3622005 0.5049923 0.5345185 0.7983025
#> sample_6 0.4896264 0.6917571 0.5843682 0.3855743 0.6970167 0.5290387 0.5568443
#> gene388 gene389 gene390 gene391 gene392 gene393 gene394
#> sample_1 0.5981750 0.7050881 0.7050881 0.4369159 0.5799914 0.5185959 0.6816468
#> sample_2 0.4752904 0.4618639 0.5807513 0.2463280 0.6449674 0.3870092 0.8001653
#> sample_3 0.5777868 0.5070457 0.6638675 0.3976107 0.6638675 0.6525358 0.5777868
#> sample_4 0.6930432 0.7547168 0.6100247 0.4669707 0.4405403 0.7026312 0.1891678
#> sample_5 0.6256974 0.5442806 0.7939153 0.2215644 0.6115284 0.3357858 0.3357858
#> sample_6 0.6224391 0.5898397 0.3380180 0.3796751 0.7075054 0.5401951 0.1774458
#> gene395 gene396 gene397 gene398 gene399 gene400 gene401
#> sample_1 0.5247905 0.4811652 0.6875238 0.3595561 0.4811652 0.7167425 0.49369244
#> sample_2 0.6449674 0.6258355 0.5284487 0.5086161 0.5019783 0.3174300 0.59369645
#> sample_3 0.5952073 0.6411598 0.7639205 0.3539191 0.7198755 0.6468533 0.06320663
#> sample_4 0.4617070 0.5649304 0.3430057 0.4669707 0.6834184 0.6737562 0.45643211
#> sample_5 0.3987006 0.5685140 0.6723336 0.7451212 0.3987006 0.6444605 0.44483024
#> sample_6 0.7387309 0.4952919 0.5065875 0.3678381 0.2278711 0.7490601 0.58436819
#> gene402 gene403 gene404 gene405 gene406 gene407 gene408
#> sample_1 0.3201386 0.8197024 0.5247905 0.6933897 0.5309728 0.6580266 0.4559574
#> sample_2 0.2029079 0.6194330 0.6828965 0.6001497 0.5086161 0.5416035 0.6891752
#> sample_3 0.3476236 0.5010725 0.7965233 0.5308172 0.3286555 0.5308172 0.5777868
#> sample_4 0.3096290 0.7359020 0.8240363 0.3976611 0.6445436 0.5547980 0.6737562
#> sample_5 0.4397482 0.4801073 0.3987006 0.7361422 0.3831254 0.5491468 0.2820702
#> sample_6 0.7179538 0.6385932 0.6599838 0.5733921 0.5065875 0.5953001 0.4839491
#> gene409 gene410 gene411 gene412 gene413 gene414 gene415
#> sample_1 0.4622786 0.2125022 0.6580266 0.7167425 0.4049174 0.4559574 0.6698593
#> sample_2 0.6130180 0.3454407 0.9074890 0.6386026 0.6828965 0.5872303 0.7141694
#> sample_3 0.6695169 0.5894120 0.7639205 0.5602617 0.5367299 0.3476236 0.4467559
#> sample_4 0.8149041 0.5800525 0.7919264 0.5190070 0.6248770 0.0000000 0.7873054
#> sample_5 0.4499016 0.6584374 0.8588974 0.6584374 0.4397482 0.3304679 0.2657190
#> sample_6 0.6170329 0.6546519 0.7849062 0.6224391 0.6812072 0.5953001 0.8051793
#> gene416 gene417 gene418 gene419 gene420 gene421 gene422
#> sample_1 0.8253232 0.5555792 0.3660771 0.9518606 0.5309728 0.2667884 0.5061692
#> sample_2 0.6194330 0.5872303 0.2101850 0.6130180 0.5936965 0.4483816 0.2535087
#> sample_3 0.5661151 0.3349919 0.7529714 0.4528412 0.4528412 0.5426306 0.3223053
#> sample_4 0.6347296 0.6050542 0.4879155 0.4352205 0.4669707 0.6199360 0.3813897
#> sample_5 0.4244373 0.3516694 0.6350972 0.2602437 0.4750993 0.6115284 0.2820702
#> sample_6 0.7644807 0.3440083 0.4952919 0.6599838 0.1325426 0.4380985 0.2589181
#> gene423 gene424 gene425 gene426 gene427 gene428 gene429
#> sample_1 0.8477047 0.2465425 0.7399204 0.3333336 0.5061692 0.4049174 0.6162523
#> sample_2 0.6703026 0.4007481 0.5677544 0.4819830 0.6639873 0.6194330 0.4886618
#> sample_3 0.4467559 0.6125244 0.5719568 0.6638675 0.5485195 0.4890892 0.5894120
#> sample_4 0.6494362 0.2984036 0.5344088 0.6640566 0.3759423 0.6785920 0.6149853
#> sample_5 0.4950691 0.4801073 0.5540032 0.6256974 0.7762863 0.6584374 0.6584374
#> sample_6 0.6116160 0.6061883 0.7899887 0.2027755 0.4782599 0.5843682 0.4839491
#> gene430 gene431 gene432 gene433 gene434 gene435 gene436
#> sample_1 0.4622786 0.3201386 0.6933897 0.2329713 0.4559574 0.6222547 0.4496233
#> sample_2 0.4886618 0.2749558 0.5284487 0.5284487 0.4280527 0.3174300 0.5547053
#> sample_3 0.3286555 0.5777868 0.5010725 0.6582071 0.6125244 0.8712092 0.3602009
#> sample_4 0.4352205 0.5292855 0.5395217 0.6199360 0.5344088 0.4669707 0.6494362
#> sample_5 0.6162607 0.3726857 0.8157716 0.3569407 0.6304019 0.8026817 0.4801073
#> sample_6 0.3499854 0.2712383 0.4668457 0.4496339 0.7127346 0.7747126 0.1964652
#> gene437 gene438 gene439 gene440 gene441 gene442 gene443
#> sample_1 0.3135199 0.2735077 0.3984778 0.4177565 0.4049174 0.5555792 0.3267431
#> sample_2 0.3870092 0.2319190 0.4752904 0.6065902 0.6891752 0.5807513 0.4416194
#> sample_3 0.5248924 0.3539191 0.4161373 0.5189557 0.4649740 0.6411598 0.4467559
#> sample_4 0.6978418 0.3540329 0.6543192 0.8602348 0.4826958 0.5292855 0.5900832
#> sample_5 0.4499016 0.3987006 0.5540032 0.6256974 0.3144432 0.5296225 0.5877265
#> sample_6 0.4207030 0.3855743 0.5178363 0.5346226 0.4839491 0.6917571 0.6439567
#> gene444 gene445 gene446 gene447 gene448 gene449 gene450
#> sample_1 0.7283531 0.4369159 0.4622786 0.6042125 0.3201386 0.3530213 0.4811652
#> sample_2 0.5481610 0.2319190 0.3662914 0.6130180 0.3938859 0.4618639 0.6449674
#> sample_3 0.5602617 0.4528412 0.5367299 0.7198755 0.5426306 0.6751555 0.6468533
#> sample_4 0.6248770 0.6050542 0.7919264 0.3922491 0.3263731 0.6882354 0.4617070
#> sample_5 0.4499016 0.4448302 0.7585271 0.6491285 0.7718587 0.7451212 0.4141756
#> sample_6 0.5346226 0.6061883 0.5178363 0.7696015 0.7022661 0.5733921 0.6917571
#> gene451 gene452 gene454 gene455 gene456 gene457 gene458
#> sample_1 0.4305426 0.7399204 0.7283531 0.4432761 0.2935785 0.7050881 0.4113436
#> sample_2 0.5284487 0.5742593 0.3454407 0.5807513 0.2749558 0.5807513 0.7574519
#> sample_3 0.1521538 0.6920059 0.5485195 0.6976011 0.2121818 0.7584511 0.3031712
#> sample_4 0.3813897 0.7780377 0.5086861 0.5138519 0.4298893 0.6000739 0.4983224
#> sample_5 0.3090779 0.8503338 0.7451212 0.6304019 0.3987006 0.5636868 0.5540032
#> sample_6 0.2650852 0.7127346 0.6224391 0.8353081 0.2835028 0.5568443 0.4207030
#> gene459 gene460 gene461 gene462 gene463 gene464 gene465
#> sample_1 0.3725845 0.6875238 0.5678094 0.6875238 0.3399101 0.6282455 0.4113436
#> sample_2 0.3801180 0.3938859 0.5019783 0.6513197 0.4007481 0.4075957 0.3314655
#> sample_3 0.2903452 0.5367299 0.6807831 0.4528412 0.6125244 0.6182740 0.2774625
#> sample_4 0.2927719 0.5598693 0.5598693 0.6298082 0.6591926 0.2758003 0.3319296
#> sample_5 0.2103980 0.7316402 0.6304019 0.4650518 0.5540032 0.3410920 0.3090779
#> sample_6 0.5788857 0.8253023 0.7387309 0.6493096 0.6170329 0.6385932 0.4611206
#> gene466 gene467 gene468 gene469 gene470 gene471 gene472
#> sample_1 0.5061692 0.3201386 0.2869027 0.5061692 0.5555792 0.3201386 0.2533059
#> sample_2 0.4144290 0.5284487 0.4075957 0.5019783 0.5350328 0.3103894 0.5807513
#> sample_3 0.6638675 0.4467559 0.4589139 0.7143228 0.6695169 0.7254176 0.5010725
#> sample_4 0.6050542 0.7216973 0.4298893 0.5395217 0.5547980 0.6396414 0.4931244
#> sample_5 0.8201191 0.4499016 0.6304019 0.6815534 0.7540668 0.5491468 0.5000358
#> sample_6 0.7542100 0.5401951 0.6439567 0.4553833 0.7127346 0.5178363 0.5568443
#> gene473 gene474 gene475 gene476 gene477 gene478 gene479
#> sample_1 0.3135199 0.6933897 0.2465425 0.4432761 0.6698593 0.3267431 0.06529691
#> sample_2 0.4752904 0.8062217 0.3103894 0.3384606 0.6954418 0.3314655 0.52185130
#> sample_3 0.4467559 0.4467559 0.3095632 0.7198755 0.4037993 0.2384696 0.50107251
#> sample_4 0.3650116 0.6640566 0.1055066 0.4931244 0.6978418 0.2587125 0.49312440
#> sample_5 0.7585271 0.6537874 0.2326792 0.6067868 0.5685140 0.1307478 0.49506913
#> sample_6 0.4839491 0.5122177 0.4207030 0.6546519 0.6007497 0.5457562 0.61703293
#> gene480 gene481 gene482 gene483 gene484 gene485 gene486
#> sample_1 0.5309728 0.3790781 0.1711533 0.3725845 0.6401924 0.2533059 0.4305426
#> sample_2 0.3524058 0.6766057 0.3593561 0.4280527 0.7513039 0.2174458 0.6386026
#> sample_3 0.7419811 0.4345470 0.4950870 0.5661151 0.4222868 0.4649740 0.4467559
#> sample_4 0.9829511 0.4722234 0.4298893 0.5649304 0.3485254 0.5649304 0.6445436
#> sample_5 0.8331147 0.4193119 0.4244373 0.5148746 0.4851049 0.4801073 0.4950691
#> sample_6 0.4952919 0.3017963 0.2896143 0.1838004 0.5009455 0.3017963 0.6653052
#> gene487 gene488 gene489 gene490 gene491 gene492 gene493
#> sample_1 0.5678094 0.5247905 0.0219191 0.3790781 0.4432761 0.3790781 0.4113436
#> sample_2 0.4144290 0.3870092 0.3314655 0.5612364 0.5481610 0.5872303 0.6130180
#> sample_3 0.6182740 0.8073105 0.3159412 0.7802674 0.8341052 0.5719568 0.6009911
#> sample_4 0.3595283 0.2587125 0.1176311 0.5138519 0.2587125 0.5800525 0.4564321
#> sample_5 0.5345185 0.7406359 0.3726857 0.3569407 0.4038700 0.2602437 0.4801073
#> sample_6 0.5513059 0.7387309 0.1964652 0.7593502 0.4839491 0.3440083 0.3796751
#> gene494 gene495 gene496 gene497 gene498 gene499 gene500
#> sample_1 0.4369159 0.5185959 0.5123888 0.5309728 0.3068870 0.4811652 0.5123888
#> sample_2 0.3938859 0.1292261 0.5416035 0.1956144 0.8062217 0.6001497 0.5936965
#> sample_3 0.4770565 0.5010725 0.5248924 0.3349919 0.6411598 0.6863999 0.3914090
#> sample_4 0.5950835 0.5649304 0.5035097 0.4983224 0.5699813 0.5950835 0.5598693
#> sample_5 0.5394045 0.1879085 0.5345185 0.5540032 0.5877265 0.4038700 0.4397482
#> sample_6 0.4782599 0.5346226 0.2773774 0.6224391 0.5678873 0.8051793 0.5122177
#> gene501 gene502 gene503 gene504 gene505 gene506 gene507
#> sample_1 0.4685870 0.3267431 0.6992444 0.26678840 0.5799914 0.5678094 0.3464726
#> sample_2 0.6954418 0.5086161 0.4886618 0.03087175 0.5677544 0.1736354 0.7758264
#> sample_3 0.6976011 0.6920059 0.5777868 0.70318569 0.7802674 0.5426306 0.8019219
#> sample_4 0.7216973 0.4030614 0.6882354 0.54462421 0.8194743 0.2183804 0.7026312
#> sample_5 0.6256974 0.4900922 0.5148746 0.51980064 0.7540668 0.5198006 0.5148746
#> sample_6 0.8601627 0.3737631 0.4496339 0.64930956 0.8253023 0.6385932 0.5568443
#> gene508 gene509 gene510 gene511 gene512 gene513 gene514
#> sample_1 0.6580266 0.7456878 0.3002399 0.5617003 0.5555792 0.5371428 0.5309728
#> sample_2 0.5152405 0.4483816 0.2535087 0.3244553 0.8062217 0.7635883 0.6954418
#> sample_3 0.5426306 0.6182740 0.3476236 0.6920059 0.5426306 0.8817243 0.5719568
#> sample_4 0.3319296 0.6347296 0.4245468 0.4030614 0.6298082 0.7873054 0.7406190
#> sample_5 0.5296225 0.7629792 0.4038700 0.5345185 0.6630784 0.5588499 0.6723336
#> sample_6 0.3973344 0.6224391 0.3855743 0.5346226 0.5678873 0.5009455 0.5401951
#> gene515 gene516 gene517 gene518 gene519 gene520 gene521
#> sample_1 0.5921256 0.4685870 0.7857617 0.04368401 0.5678094 0.4113436 0.4049174
#> sample_2 0.7016964 0.5284487 0.8423246 0.13666991 0.3870092 0.4618639 0.6513197
#> sample_3 0.5010725 0.4770565 0.4467559 0.54263064 0.6354552 0.5248924 0.5952073
#> sample_4 0.6149853 0.5241515 0.4138272 0.30962903 0.7547168 0.6000739 0.6494362
#> sample_5 0.5394045 0.2929097 0.1480390 0.47509926 0.5198006 0.6630784 0.6115284
#> sample_6 0.8051793 0.6278345 0.4148797 0.69175705 0.4496339 0.5898397 0.5953001
#> gene522 gene523 gene524 gene525 gene526 gene527 gene529
#> sample_1 0.2125022 0.5371428 0.1222039 0.4811652 0.3002399 0.4049174 0.5185959
#> sample_2 0.5872303 0.5612364 0.8602267 0.5218513 0.2820735 0.6891752 0.5612364
#> sample_3 0.5661151 0.6976011 0.4406578 0.5070457 0.6125244 0.4037993 0.4830791
#> sample_4 0.4722234 0.5086861 0.5649304 0.5190070 0.5344088 0.4191927 0.6149853
#> sample_5 0.2159877 0.4750993 0.5491468 0.5099385 0.6350972 0.3251382 0.6953171
#> sample_6 0.6970167 0.5733921 0.3855743 0.4090439 0.5178363 0.6385932 0.4782599
#> gene530 gene531 gene533 gene534 gene535 gene536 gene537
#> sample_1 0.5739064 0.4874351 0.3267431 0.5247905 0.3855582 0.1432771 0.3464726
#> sample_2 0.7327897 0.4886618 0.5218513 0.6513197 0.4280527 0.3801180 0.3662914
#> sample_3 0.5543965 0.4830791 0.4589139 0.7198755 0.6297394 0.4950870 0.5485195
#> sample_4 0.7026312 0.7406190 0.6930432 0.6591926 0.4931244 0.3976611 0.5900832
#> sample_5 0.4750993 0.7895202 0.4650518 0.7451212 0.4801073 0.5247166 0.6491285
#> sample_6 0.2650852 0.6385932 0.6170329 0.6812072 0.6599838 0.8102240 0.7899887
#> gene538 gene539 gene540 gene541 gene543 gene544 gene545
#> sample_1 0.6992444 0.2056490 0.4369159 0.5309728 0.4049174 0.5981750 0.4305426
#> sample_2 0.6001497 0.4551297 0.4551297 0.5677544 0.3454407 0.4551297 0.5284487
#> sample_3 0.7965233 0.3413146 0.4161373 0.4890892 0.5308172 0.6411598 0.6297394
#> sample_4 0.8285899 0.2415070 0.3976611 0.5497163 0.4931244 0.7216973 0.5800525
#> sample_5 0.9552482 0.3622005 0.3779112 0.3090779 0.5442806 0.5148746 0.5296225
#> sample_6 0.5898397 0.4896264 0.4952919 0.2341090 0.3259977 0.5401951 0.6759169
#> gene546 gene547 gene548 gene549 gene550 gene551 gene552
#> sample_1 0.4999371 0.2329713 0.4496233 0.5739064 0.4177565 0.6698593 0.6580266
#> sample_2 0.4886618 0.4886618 0.6130180 0.4819830 0.7513039 0.7079389 0.7265948
#> sample_3 0.5602617 0.7529714 0.4528412 0.4830791 0.5661151 0.8019219 0.5010725
#> sample_4 0.6445436 0.4458488 0.5138519 0.5344088 0.6396414 0.4405403 0.3374738
#> sample_5 0.7226107 0.6723336 0.2874961 0.5540032 0.3357858 0.8244588 0.5829377
#> sample_6 0.4782599 0.7283622 0.5122177 0.6706162 0.6599838 0.6706162 0.5513059
#> gene553 gene554 gene555 gene556 gene557 gene558 gene559
#> sample_1 0.7686507 0.5739064 0.7800685 0.7283531 0.2533059 0.4999371 0.4305426
#> sample_2 0.1809782 0.4819830 0.6001497 0.7141694 0.2749558 0.7635883 0.5284487
#> sample_3 0.7087596 0.5248924 0.6009911 0.5189557 0.3031712 0.6525358 0.6807831
#> sample_4 0.4983224 0.8376723 0.5446242 0.3813897 0.5900832 0.6882354 0.4138272
#> sample_5 0.2382175 0.6304019 0.6953171 0.5781394 0.4499016 0.3883284 0.5099385
#> sample_6 0.6116160 0.8601627 0.5065875 0.3973344 0.5898397 0.8552099 0.7490601
#> gene560 gene561 gene562 gene563 gene564 gene565 gene566
#> sample_1 0.6222547 0.1711533 0.6698593 0.6102383 0.5433004 0.3920247 0.3267431
#> sample_2 0.5807513 0.5152405 0.4953268 0.6065902 0.3801180 0.4348431 0.6954418
#> sample_3 0.5367299 0.5952073 0.5189557 0.7254176 0.7911148 0.7254176 0.7364704
#> sample_4 0.5446242 0.5395217 0.4564321 0.5344088 0.8103254 0.6882354 0.8736751
#> sample_5 0.5345185 0.4801073 0.5925057 0.4750993 0.8417397 0.6209836 0.4090283
#> sample_6 0.6599838 0.5898397 0.6170329 0.4782599 0.5733921 0.5568443 0.6332192
#> gene567 gene568 gene569 gene571 gene572 gene574 gene575
#> sample_1 0.6042125 0.4305426 0.7800685 0.5494459 0.3595561 0.3920247 0.5247905
#> sample_2 0.4007481 0.4212480 0.4348431 0.2174458 0.8661722 0.5350328 0.8122668
#> sample_3 0.6240123 0.4161373 0.2580312 0.3539191 0.7639205 0.7309492 0.6525358
#> sample_4 0.5750220 0.4879155 0.4084501 0.2814703 0.5900832 0.8194743 0.5800525
#> sample_5 0.4600123 0.4295517 0.3674488 0.5781394 0.6020359 0.7361422 0.6491285
#> sample_6 0.6599838 0.2027755 0.6170329 0.6599838 0.4496339 0.8303098 0.4496339
#> gene576 gene577 gene578 gene579 gene580 gene581 gene582
#> sample_1 0.5433004 0.6401924 0.2397644 0.3920247 0.6757587 0.3855582 0.6520933
#> sample_2 0.7389728 0.4886618 0.4551297 0.4551297 0.5019783 0.5872303 0.6703026
#> sample_3 0.3789658 0.3914090 0.3914090 0.4284233 0.6240123 0.4037993 0.3976107
#> sample_4 0.6298082 0.5086861 0.2472554 0.3374738 0.4352205 0.4084501 0.7687354
#> sample_5 0.4600123 0.1652069 0.3410920 0.3831254 0.4295517 0.3674488 0.5540032
#> sample_6 0.5953001 0.4148797 0.5122177 0.6170329 0.8102240 0.3855743 0.6061883
#> gene583 gene584 gene585 gene586 gene587 gene588 gene589
#> sample_1 0.4049174 0.4559574 0.5185959 0.4369159 0.5247905 0.5061692 0.5123888
#> sample_2 0.5481610 0.5936965 0.5019783 0.4618639 0.6703026 0.5481610 0.4280527
#> sample_3 0.2967653 0.5543965 0.5010725 0.2774625 0.5367299 0.6125244 0.7474814
#> sample_4 0.5086861 0.4931244 0.2758003 0.5086861 0.8647229 0.4458488 0.6591926
#> sample_5 0.1991795 0.2437430 0.3304679 0.3144432 0.7807057 0.5781394 0.5685140
#> sample_6 0.4380985 0.5788857 0.7127346 0.6170329 0.5401951 0.6224391 0.4725588
#> gene590 gene591 gene592 gene593 gene594 gene595 gene596
#> sample_1 0.6162523 0.5247905 0.6992444 0.4305426 0.5123888 0.3725845 0.3855582
#> sample_2 0.4618639 0.4685841 0.2749558 0.2463280 0.7758264 0.4685841 0.5019783
#> sample_3 0.3914090 0.6182740 0.6125244 0.5248924 0.4467559 0.3349919 0.2839109
#> sample_4 0.6543192 0.7780377 0.3208042 0.7453271 0.6543192 0.4138272 0.3208042
#> sample_5 0.4244373 0.7451212 0.7226107 0.3569407 0.4801073 0.3197966 0.2271282
#> sample_6 0.4839491 0.5513059 0.6546519 0.6007497 0.6332192 0.3737631 0.5843682
#> gene598 gene599 gene600 gene601 gene602 gene603 gene604
#> sample_1 0.7857617 0.6102383 0.5494459 0.3333336 0.5799914 0.5860645 0.3725845
#> sample_2 0.4212480 0.7389728 0.7451442 0.3801180 0.4886618 0.7141694 0.6130180
#> sample_3 0.5070457 0.5777868 0.5308172 0.5719568 0.5719568 0.7143228 0.6411598
#> sample_4 0.4564321 0.4722234 0.6347296 0.4084501 0.6737562 0.5850729 0.4352205
#> sample_5 0.5781394 0.5049923 0.6815534 0.2983112 0.6444605 0.4851049 0.4193119
#> sample_6 0.4438723 0.7747126 0.4207030 0.7798142 0.4380985 0.6061883 0.2712383
#> gene605 gene606 gene607 gene608 gene609 gene610 gene611
#> sample_1 0.7050881 0.4113436 0.5678094 0.4811652 0.5371428 0.5309728 0.5061692
#> sample_2 0.4886618 0.4752904 0.7203880 0.3244553 0.5086161 0.6576597 0.6130180
#> sample_3 0.7419811 0.3539191 0.6067634 0.4222868 0.3223053 0.6067634 0.4950870
#> sample_4 0.7169444 0.6298082 0.3096290 0.6494362 0.4669707 0.5190070 0.5292855
#> sample_5 0.8026817 0.2602437 0.6769479 0.4549623 0.4038700 0.4346554 0.5491468
#> sample_6 0.3499854 0.4839491 0.6706162 0.7849062 0.4725588 0.7849062 0.5457562
#> gene612 gene613 gene614 gene615 gene616 gene617 gene618
#> sample_1 0.7971167 0.1292443 0.4811652 0.7341421 0.5678094 0.5739064 0.7971167
#> sample_2 0.5742593 0.5152405 0.4280527 0.5218513 0.4144290 0.4886618 0.4551297
#> sample_3 0.5894120 0.6525358 0.5894120 0.6182740 0.5485195 0.5543965 0.5248924
#> sample_4 0.6834184 0.5446242 0.4458488 0.4826958 0.4722234 0.5292855 0.4138272
#> sample_5 0.4448302 0.8201191 0.5345185 0.7090026 0.4244373 0.5442806 0.3987006
#> sample_6 0.6439567 0.5234433 0.7542100 0.4148797 0.4380985 0.7950617 0.4725588
#> gene619 gene620 gene621 gene622 gene623 gene624 gene625
#> sample_1 0.5617003 0.7167425 0.3068870 0.6580266 0.5309728 0.6875238 0.4496233
#> sample_2 0.4618639 0.4144290 0.4819830 0.2535087 0.5086161 0.1515066 0.6258355
#> sample_3 0.1656005 0.2903452 0.3413146 0.5719568 0.7087596 0.3476236 0.5426306
#> sample_4 0.3485254 0.3208042 0.3208042 0.6050542 0.6882354 0.5800525 0.7406190
#> sample_5 0.1537753 0.1594979 0.5000358 0.6953171 0.6397834 0.5829377 0.6998876
#> sample_6 0.3973344 0.6706162 0.2527371 0.4725588 0.5122177 0.8353081 0.3855743
#> gene626 gene627 gene628 gene629 gene630 gene631 gene632
#> sample_1 0.6639486 0.6102383 0.8197024 0.2125022 0.5371428 0.1292443 0.5309728
#> sample_2 0.5416035 0.3454407 0.9942946 0.4280527 0.4685841 0.5218513 0.4618639
#> sample_3 0.5308172 0.5894120 0.5952073 0.5426306 0.6240123 0.3914090 0.7087596
#> sample_4 0.4564321 0.4826958 0.6199360 0.5850729 0.7733909 0.7311761 0.3096290
#> sample_5 0.1480390 0.4295517 0.6537874 0.5099385 0.4090283 0.7180832 0.3304679
#> sample_6 0.8798839 0.6439567 0.6493096 0.5953001 0.4323124 0.4553833 0.7593502
#> gene633 gene634 gene635 gene636 gene637 gene638 gene639
#> sample_1 0.3002399 0.4369159 0.5799914 0.2125022 0.3790781 0.5123888 0.5555792
#> sample_2 0.4953268 0.1956144 0.6828965 0.5350328 0.5086161 0.6194330 0.4618639
#> sample_3 0.3095632 0.2774625 0.4467559 0.6920059 0.7254176 0.6297394 0.6976011
#> sample_4 0.3704829 0.4138272 0.5446242 0.5035097 0.5241515 0.4669707 0.5138519
#> sample_5 0.2820702 0.1249563 0.4499016 0.6769479 0.6067868 0.2929097 0.4900922
#> sample_6 0.4323124 0.4090439 0.6007497 0.6170329 0.6061883 0.7849062 0.4496339
#> gene640 gene641 gene642 gene643 gene644 gene645 gene646
#> sample_1 0.6162523 0.4241562 0.3984778 0.3660771 0.6282455 0.1711533 0.4936924
#> sample_2 0.2391315 0.5152405 0.4685841 0.3662914 0.4483816 0.6513197 0.6258355
#> sample_3 0.4222868 0.5248924 0.5952073 0.6067634 0.6067634 0.7309492 0.6976011
#> sample_4 0.3976611 0.3540329 0.5395217 0.6100247 0.6149853 0.6689111 0.5598693
#> sample_5 0.2983112 0.1935506 0.5000358 0.5733315 0.6020359 0.7406359 0.8026817
#> sample_6 0.3139240 0.5898397 0.9382028 0.4031955 0.3499854 0.6224391 0.7849062
#> gene647 gene648 gene649 gene650 gene651 gene652 gene653
#> sample_1 0.7225532 0.5555792 0.2600545 0.3068870 0.7225532 0.5309728 0.62225474
#> sample_2 0.3454407 0.6513197 0.5152405 0.5807513 0.7940977 0.5416035 0.06145295
#> sample_3 0.3664693 0.3095632 0.8922016 0.4099748 0.7748286 0.5189557 0.60676345
#> sample_4 0.4511461 0.2758003 0.3813897 0.4458488 0.7965389 0.5750220 0.37048291
#> sample_5 0.5394045 0.4499016 0.6304019 0.3516694 0.4900922 0.5685140 0.51980064
#> sample_6 0.7593502 0.2278711 0.8452772 0.7179538 0.8102240 0.6759169 0.53462264
#> gene654 gene655 gene656 gene657 gene658 gene659 gene660
#> sample_1 0.7629259 0.3920247 0.2465425 0.6992444 0.5739064 0.3595561 0.1362687
#> sample_2 0.7574519 0.3174300 0.5481610 0.7079389 0.4685841 0.5350328 0.6130180
#> sample_3 0.7254176 0.6182740 0.5602617 0.6297394 0.4710215 0.5189557 0.4890892
#> sample_4 0.6640566 0.7311761 0.4879155 0.3704829 0.5699813 0.4352205 0.5649304
#> sample_5 0.8114162 0.6304019 0.4600123 0.8026817 0.5877265 0.1594979 0.7718587
#> sample_6 0.7696015 0.7283622 0.6653052 0.9478020 0.5843682 0.5733921 0.2027755
#> gene661 gene662 gene663 gene664 gene665 gene666 gene667
#> sample_1 0.5185959 0.4559574 0.4241562 0.64019237 0.5494459 0.5185959 0.8532749
#> sample_2 0.3801180 0.3593561 0.4886618 0.33146552 0.4348431 0.4483816 0.6766057
#> sample_3 0.5010725 0.5602617 0.6468533 0.04927856 0.7198755 0.5485195 0.6638675
#> sample_4 0.1950377 0.4511461 0.5699813 0.27580027 0.5138519 0.8467217 0.3922491
#> sample_5 0.5733315 0.6162607 0.1991795 0.28749608 0.4950691 0.5540032 0.5394045
#> sample_6 0.7798142 0.5346226 0.5234433 0.39733443 0.5898397 0.5953001 0.6864872
#> gene668 gene669 gene670 gene671 gene672 gene673 gene674
#> sample_1 0.5617003 0.22616332 0.5981750 0.6580266 0.4241562 0.4432761 0.2935785
#> sample_2 0.7016964 0.16627583 0.3938859 0.5677544 0.7513039 0.4886618 0.5284487
#> sample_3 0.7529714 0.42228678 0.6525358 0.6067634 0.7087596 0.6182740 0.5602617
#> sample_4 0.6591926 0.56998130 0.5190070 0.8512342 0.6834184 0.7074114 0.5800525
#> sample_5 0.6584374 0.42443727 0.5540032 0.7895202 0.7895202 0.7585271 0.5925057
#> sample_6 0.2589181 0.05379551 0.6653052 0.5843682 0.8202855 0.4668457 0.6224391
#> gene675 gene676 gene678 gene679 gene680 gene681 gene682
#> sample_1 0.4559574 0.6102383 0.4622786 0.7225532 0.3002399 0.3135199 0.3135199
#> sample_2 0.5807513 0.4280527 0.5807513 0.6322253 0.6891752 0.4280527 0.4483816
#> sample_3 0.8234168 0.5248924 0.4037993 0.2515252 0.4950870 0.5952073 0.5248924
#> sample_4 0.7121824 0.5850729 0.4458488 0.4931244 0.5950835 0.6882354 0.5497163
#> sample_5 0.5636868 0.6953171 0.4090283 0.3410920 0.4346554 0.7271297 0.7451212
#> sample_6 0.3619002 0.4668457 0.5401951 0.4265139 0.3619002 0.5122177 0.4031955
#> gene683 gene684 gene685 gene686 gene687 gene689 gene690
#> sample_1 0.2935785 0.7341421 0.3333336 0.3267431 0.5739064 0.4049174 0.6520933
#> sample_2 0.3593561 0.5677544 0.4551297 0.6001497 0.4007481 0.0000000 0.1956144
#> sample_3 0.2645227 0.3664693 0.5367299 0.4890892 0.6354552 0.6920059 0.3413146
#> sample_4 0.5446242 0.5800525 0.4617070 0.4298893 0.5750220 0.5292855 0.5497163
#> sample_5 0.5685140 0.5636868 0.6256974 0.1652069 0.3304679 0.7807057 0.5491468
#> sample_6 0.5234433 0.7127346 0.5513059 0.6546519 0.5457562 0.5009455 0.4438723
#> gene691 gene692 gene693 gene694 gene695 gene696 gene697
#> sample_1 0.2533059 0.2667884 0.8027786 0.4874351 0.4369159 0.6992444 0.4685870
#> sample_2 0.3384606 0.3801180 0.5416035 0.2174458 0.3801180 0.5086161 0.9133488
#> sample_3 0.3159412 0.5543965 0.3976107 0.5010725 0.2645227 0.5894120 0.8764715
#> sample_4 0.4931244 0.9047574 0.7406190 0.3208042 0.4084501 0.3813897 0.7264412
#> sample_5 0.3410920 0.7361422 0.6537874 0.4700808 0.2820702 0.4090283 0.7271297
#> sample_6 0.5733921 0.6007497 0.5346226 0.4148797 0.5401951 0.7644807 0.7127346
#> gene698 gene699 gene700 gene701 gene702 gene703 gene704
#> sample_1 0.4874351 0.3135199 0.5247905 0.6042125 0.6757587 0.5617003 0.1572466
#> sample_2 0.8780308 0.5350328 0.5677544 0.3384606 0.3384606 0.5481610 0.4886618
#> sample_3 0.5836052 0.7143228 0.5426306 0.3976107 0.7474814 0.7309492 0.6582071
#> sample_4 0.3813897 0.5900832 0.3096290 0.2984036 0.6785920 0.5699813 0.3152229
#> sample_5 0.2766322 0.5000358 0.5685140 0.5442806 0.7226107 0.6444605 0.4397482
#> sample_6 0.5843682 0.4380985 0.4611206 0.5953001 0.8303098 0.8552099 0.5788857
#> gene705 gene706 gene707 gene708 gene709 gene710 gene711
#> sample_1 0.3984778 0.3201386 0.7686507 0.4496233 0.4369159 0.1009863 0.2600545
#> sample_2 0.5547053 0.1366699 0.4953268 0.8602267 0.2029079 0.7265948 0.6194330
#> sample_3 0.9337386 0.3413146 0.7087596 0.7474814 0.2967653 0.5952073 0.5010725
#> sample_4 0.7026312 0.4405403 0.6248770 0.6000739 0.4138272 0.4879155 0.3595283
#> sample_5 0.7983025 0.4499016 0.8070529 0.4650518 0.5345185 0.3883284 0.2711817
#> sample_6 0.7490601 0.6116160 0.9140552 0.6970167 0.3678381 0.6007497 0.6116160
#> gene712 gene713 gene715 gene716 gene718 gene719 gene720
#> sample_1 0.4559574 0.5371428 0.6401924 0.5981750 0.7456878 0.4305426 0.4811652
#> sample_2 0.4348431 0.4953268 0.6828965 0.5936965 0.5547053 0.3384606 0.3174300
#> sample_3 0.3031712 0.5189557 0.3789658 0.3476236 0.4037993 0.7584511 0.2774625
#> sample_4 0.3759423 0.5497163 0.2644214 0.3319296 0.5344088 0.5800525 0.6737562
#> sample_5 0.2437430 0.3037006 0.3357858 0.4141756 0.1935506 0.4499016 0.4038700
#> sample_6 0.4611206 0.2773774 0.6493096 0.3559493 0.4265139 0.3973344 0.3678381
#> gene721 gene722 gene723 gene725 gene726 gene727 gene728
#> sample_1 0.7456878 0.3399101 0.6639486 0.2397644 0.6222547 0.5739064 0.4748825
#> sample_2 0.7141694 0.4551297 0.6513197 0.1662758 0.5936965 0.3174300 0.5872303
#> sample_3 0.6240123 0.7748286 0.5602617 0.4528412 0.4161373 0.5777868 0.5894120
#> sample_4 0.6445436 0.5900832 0.7965389 0.3813897 0.3868253 0.5850729 0.4458488
#> sample_5 0.6723336 0.7807057 0.6491285 0.5540032 0.5829377 0.4038700 0.4295517
#> sample_6 0.6970167 0.5009455 0.3914607 0.1964652 0.3973344 0.6546519 0.6917571
#> gene729 gene731 gene732 gene733 gene734 gene735 gene736
#> sample_1 0.5921256 0.7109208 0.3595561 0.6042125 0.2261633 0.6042125 0.5247905
#> sample_2 0.6513197 0.5481610 0.5936965 0.5677544 0.5086161 0.5019783 0.6065902
#> sample_3 0.7419811 0.5602617 0.6751555 0.6182740 0.6411598 0.6067634 0.5719568
#> sample_4 0.5649304 0.4879155 0.6591926 0.4245468 0.4511461 0.5900832 0.7169444
#> sample_5 0.5000358 0.4900922 0.5972755 0.4090283 0.3987006 0.4244373 0.7135472
#> sample_6 0.6864872 0.7798142 0.4090439 0.4323124 0.4496339 0.6007497 0.6493096
#> gene737 gene738 gene740 gene741 gene742 gene743 gene744
#> sample_1 0.4685870 0.8421245 0.2056490 0.5921256 0.3068870 0.5617003 0.5433004
#> sample_2 0.4144290 0.5481610 0.3732121 0.5416035 0.2678225 0.6703026 0.7016964
#> sample_3 0.3602009 0.5836052 0.4467559 0.6525358 0.1114379 0.5426306 0.4890892
#> sample_4 0.4722234 0.5497163 0.3704829 0.6298082 0.3540329 0.4826958 0.5138519
#> sample_5 0.5296225 0.7271297 0.5636868 0.6067868 0.5049923 0.5491468 0.4600123
#> sample_6 0.2403325 0.7022661 0.5122177 0.3559493 0.2403325 0.6917571 0.5513059
#> gene745 gene746 gene747 gene748 gene749 gene750 gene751
#> sample_1 0.4369159 0.2125022 0.4177565 0.6933897 0.5371428 0.6222547 0.7283531
#> sample_2 0.4819830 0.2246905 0.5019783 0.4752904 0.7697131 0.7016964 0.6639873
#> sample_3 0.4589139 0.5308172 0.6582071 0.4528412 0.6976011 0.5308172 0.7364704
#> sample_4 0.2701173 0.7593984 0.6591926 0.5900832 0.6396414 0.6050542 0.6543192
#> sample_5 0.2874961 0.4851049 0.7271297 0.7939153 0.4950691 0.4295517 0.5049923
#> sample_6 0.4896264 0.8001252 0.7283622 0.9285695 0.6493096 0.8001252 0.5843682
#> gene752 gene753 gene754 gene755 gene756 gene757 gene759
#> sample_1 0.3530213 0.2193403 0.3530213 0.5799914 0.2329713 0.5309728 0.4622786
#> sample_2 0.2535087 0.6449674 0.2101850 0.2463280 0.3593561 0.7203880 0.5936965
#> sample_3 0.5130068 0.6067634 0.3159412 0.3413146 0.5894120 0.5602617 0.4528412
#> sample_4 0.5497163 0.6298082 0.1714748 0.3868253 0.4931244 0.6930432 0.3152229
#> sample_5 0.6020359 0.7629792 0.5000358 0.3516694 0.6491285 0.4950691 0.6397834
#> sample_6 0.6278345 0.8402972 0.4438723 0.5733921 0.3855743 0.5178363 0.5623714
#> gene760 gene761 gene762 gene763 gene764 gene765 gene766
#> sample_1 0.5981750 0.2125022 0.3068870 0.8365342 0.4999371 0.6757587 0.6042125
#> sample_2 0.2319190 0.3938859 0.5284487 0.5612364 0.5481610 0.7016964 0.6576597
#> sample_3 0.5189557 0.4099748 0.3976107 0.5426306 0.5426306 0.3286555 0.8126892
#> sample_4 0.4564321 0.4722234 0.3096290 0.6882354 0.5446242 0.6149853 0.8331352
#> sample_5 0.6953171 0.5198006 0.4650518 0.5345185 0.7271297 0.7406359 0.5781394
#> sample_6 0.6546519 0.4839491 0.5346226 0.5733921 0.6007497 0.4090439 0.3139240
#> gene768 gene769 gene770 gene771 gene772 gene773 gene774
#> sample_1 0.4685870 0.6520933 0.3790781 0.4496233 0.4748825 0.4559574 0.5921256
#> sample_2 0.3593561 0.4953268 0.6258355 0.5086161 0.6322253 0.5742593 0.5218513
#> sample_3 0.2253553 0.5543965 0.4406578 0.4770565 0.4710215 0.4649740 0.4589139
#> sample_4 0.3319296 0.8512342 0.6199360 0.6100247 0.5547980 0.4931244 0.5446242
#> sample_5 0.4600123 0.3674488 0.6723336 0.5781394 0.6584374 0.3516694 0.5588499
#> sample_6 0.4782599 0.7075054 0.8253023 0.4668457 0.6332192 0.5898397 0.3199675
#> gene775 gene776 gene777 gene778 gene779 gene780 gene781
#> sample_1 0.5617003 0.3068870 0.5247905 0.5061692 0.7167425 0.4049174 0.6222547
#> sample_2 0.5742593 0.6065902 0.3870092 0.3801180 0.6258355 0.6891752 0.5872303
#> sample_3 0.7364704 0.7584511 0.6751555 0.4950870 0.4467559 0.5367299 0.6695169
#> sample_4 0.5699813 0.6834184 0.6396414 0.5344088 0.5598693 0.7547168 0.4826958
#> sample_5 0.5972755 0.5972755 0.5781394 0.6815534 0.4750993 0.4851049 0.4397482
#> sample_6 0.7644807 0.4090439 0.4438723 0.6493096 0.8001252 0.6599838 0.8001252
#> gene782 gene783 gene784 gene785 gene786 gene787 gene788
#> sample_1 0.2397644 0.5617003 0.6401924 0.4305426 0.7456878 0.4113436 0.4748825
#> sample_2 0.3454407 0.6766057 0.2678225 0.5481610 0.6065902 0.4953268 0.5086161
#> sample_3 0.4345470 0.6638675 0.7529714 0.4222868 0.6240123 0.3851940 0.5070457
#> sample_4 0.6396414 0.5547980 0.3595283 0.5900832 0.6834184 0.5395217 0.4030614
#> sample_5 0.4801073 0.6115284 0.5636868 0.4950691 0.4750993 0.3726857 0.5636868
#> sample_6 0.4380985 0.3078669 0.7231630 0.7593502 0.5843682 0.6653052 0.3855743
#> gene789 gene790 gene791 gene792 gene793 gene794 gene795
#> sample_1 0.6401924 0.5981750 0.3333336 0.9138940 0.04368401 0.4113436 0.5433004
#> sample_2 0.6703026 0.3314655 0.5872303 0.5872303 0.21018499 0.4212480 0.4483816
#> sample_3 0.5777868 0.6067634 0.4099748 0.7031857 0.47102152 0.6695169 0.4830791
#> sample_4 0.7826759 0.6494362 0.3922491 0.8285899 0.25871250 0.7640713 0.5598693
#> sample_5 0.6677105 0.7316402 0.3935201 0.5296225 0.46001234 0.5588499 0.6209836
#> sample_6 0.4323124 0.7127346 0.5623714 0.6224391 0.22161891 0.5898397 0.6653052
#> gene796 gene797 gene798 gene799 gene800 gene801 gene802
#> sample_1 0.4049174 0.4622786 0.2193403 0.3660771 0.7283531 0.5494459 0.3530213
#> sample_2 0.2246905 0.6576597 0.6386026 0.6703026 0.4416194 0.4886618 0.3244553
#> sample_3 0.2903452 0.3851940 0.8500647 0.4161373 0.4950870 0.4528412 0.8019219
#> sample_4 0.2008939 0.6978418 0.5598693 0.3040226 0.4191927 0.4405403 0.5900832
#> sample_5 0.3410920 0.2711817 0.8244588 0.6067868 0.4950691 0.4900922 0.6537874
#> sample_6 0.2153523 0.5678873 0.8051793 0.4896264 0.5346226 0.4553833 0.3078669
#> gene803 gene804 gene805 gene806 gene807 gene808 gene809
#> sample_1 0.3002399 0.6461485 0.3595561 0.8309338 0.3984778 0.5185959 0.3530213
#> sample_2 0.2678225 0.6001497 0.4075957 0.5284487 0.5481610 0.6828965 0.2463280
#> sample_3 0.2839109 0.5189557 0.6009911 0.6067634 0.6354552 0.6240123 0.3976107
#> sample_4 0.6050542 0.3485254 0.5800525 0.6737562 0.8376723 0.4826958 0.6882354
#> sample_5 0.4600123 0.6209836 0.3935201 0.5296225 0.7406359 0.7044494 0.8201191
#> sample_6 0.2465419 0.5346226 0.7127346 0.5401951 0.8001252 0.6970167 0.4148797
#> gene810 gene811 gene812 gene813 gene814 gene815 gene816
#> sample_1 0.3595561 0.9733484 0.5678094 0.7109208 0.2869027 0.5494459 0.4113436
#> sample_2 0.5677544 0.6639873 0.5742593 0.6639873 0.4416194 0.5547053 0.2463280
#> sample_3 0.4345470 0.4406578 0.4950870 0.6920059 0.5308172 0.7364704 0.6182740
#> sample_4 0.4826958 0.4458488 0.4298893 0.7311761 0.4458488 0.5750220 0.6050542
#> sample_5 0.4090283 0.3674488 0.6256974 0.5049923 0.5296225 0.5588499 0.5442806
#> sample_6 0.3737631 0.7439004 0.4323124 0.6224391 0.7075054 0.6812072 0.6224391
#> gene817 gene818 gene819 gene820 gene821 gene822 gene823
#> sample_1 0.5555792 0.4241562 0.8919879 0.2935785 0.5739064 0.4936924 0.3855582
#> sample_2 0.4075957 0.8062217 0.6065902 0.3732121 0.4483816 0.2820735 0.2962623
#> sample_3 0.5543965 0.5308172 0.4222868 0.5777868 0.4830791 0.4528412 0.4467559
#> sample_4 0.6050542 0.9398127 0.3430057 0.5598693 0.4826958 0.6347296 0.5750220
#> sample_5 0.6209836 0.5000358 0.5198006 0.6907380 0.4600123 0.4499016 0.6256974
#> sample_6 0.6706162 0.5843682 0.5953001 0.6599838 0.4839491 0.6706162 0.3619002
#> gene824 gene825 gene827 gene828 gene829 gene830 gene831
#> sample_1 0.7914444 0.6639486 0.3530213 0.4369159 0.4241562 0.6757587 0.6401924
#> sample_2 0.9133488 0.3938859 0.1736354 0.6001497 0.4007481 0.6954418 0.5152405
#> sample_3 0.5894120 0.5189557 0.5308172 0.4770565 0.7254176 0.6297394 0.7693796
#> sample_4 0.6834184 0.5138519 0.4617070 0.4298893 0.7359020 0.4983224 0.4826958
#> sample_5 0.4851049 0.5394045 0.2103980 0.4295517 0.5148746 0.3622005 0.4244373
#> sample_6 0.4952919 0.3973344 0.5513059 0.4725588 0.7899887 0.5843682 0.0000000
#> gene832 gene833 gene835 gene836 gene837 gene838 gene839
#> sample_1 0.4936924 0.4177565 0.7225532 0.3135199 0.4432761 0.5981750 0.5860645
#> sample_2 0.4348431 0.6828965 0.4618639 0.5019783 0.3384606 0.5019783 0.4886618
#> sample_3 0.5602617 0.8073105 0.6468533 0.2515252 0.5543965 0.4649740 0.8126892
#> sample_4 0.4669707 0.6591926 0.6298082 0.4511461 0.7264412 0.6050542 0.5547980
#> sample_5 0.7180832 0.6067868 0.6209836 0.4346554 0.2874961 0.2382175 0.3987006
#> sample_6 0.6278345 0.6917571 0.6864872 0.4265139 0.7179538 0.4265139 0.8102240
#> gene840 gene841 gene842 gene843 gene844 gene845 gene846
#> sample_1 0.5555792 0.6639486 0.4559574 0.4177565 0.4874351 0.4748825 0.4748825
#> sample_2 0.2820735 0.3384606 0.3454407 0.6001497 0.4685841 0.5416035 0.6065902
#> sample_3 0.8606561 0.6067634 0.4589139 0.6067634 0.5777868 0.3159412 0.3602009
#> sample_4 0.3922491 0.4879155 0.3540329 0.5138519 0.5497163 0.4826958 0.6000739
#> sample_5 0.7271297 0.6861501 0.4801073 0.4700808 0.6998876 0.2602437 0.3779112
#> sample_6 0.1901402 0.6061883 0.4725588 0.7283622 0.7022661 0.4952919 0.3199675
#> gene847 gene848 gene849 gene850 gene851 gene852 gene853
#> sample_1 0.4874351 0.5981750 0.4811652 0.3984778 0.5185959 0.4369159 0.1918968
#> sample_2 0.6639873 0.5872303 0.6194330 0.3870092 0.3662914 0.3314655 0.1067917
#> sample_3 0.6125244 0.5543965 0.6807831 0.5602617 0.3727242 0.4099748 0.1588849
#> sample_4 0.5497163 0.7311761 0.4191927 0.4458488 0.2067364 0.4564321 0.2758003
#> sample_5 0.5049923 0.5829377 0.5442806 0.5099385 0.4141756 0.5345185 0.2382175
#> sample_6 0.2527371 0.5009455 0.7231630 0.6493096 0.5898397 0.5178363 0.7075054
#> gene854 gene855 gene856 gene857 gene858 gene859 gene861
#> sample_1 0.5799914 0.2935785 0.3855582 0.5494459 0.5921256 0.4748825 0.5555792
#> sample_2 0.5547053 0.4551297 0.4348431 0.4144290 0.2962623 0.4007481 0.5152405
#> sample_3 0.6354552 0.4649740 0.3664693 0.7474814 0.4589139 0.3664693 0.5010725
#> sample_4 0.5598693 0.4931244 0.4030614 0.6591926 0.6050542 0.1950377 0.6149853
#> sample_5 0.6815534 0.5296225 0.2326792 0.7316402 0.4499016 0.2874961 0.4549623
#> sample_6 0.5513059 0.4148797 0.2957122 0.5953001 1.0000000 0.5843682 0.7490601
#> gene862 gene863 gene864 gene865 gene866 gene867 gene868
#> sample_1 0.4432761 0.4496233 0.5309728 0.3920247 0.6282455 0.8365342 0.4559574
#> sample_2 0.6194330 0.6194330 0.2749558 0.7327897 0.6258355 0.4618639 0.3384606
#> sample_3 0.7143228 0.5952073 0.5836052 0.6751555 0.5426306 0.7965233 0.3413146
#> sample_4 0.2758003 0.5497163 0.4458488 0.5190070 0.6834184 0.4983224 0.6000739
#> sample_5 0.4750993 0.6444605 0.4244373 0.5877265 0.7585271 0.4244373 0.5588499
#> sample_6 0.6278345 0.5953001 0.3737631 0.7022661 0.5568443 0.4496339 0.2650852
#> gene869 gene870 gene871 gene872 gene873 gene874 gene875
#> sample_1 0.6282455 0.5247905 0.3595561 0.5123888 0.5739064 0.5123888 0.4936924
#> sample_2 0.6703026 0.6258355 0.2606734 0.5742593 0.3732121 0.6639873 0.6322253
#> sample_3 0.4710215 0.6582071 0.5367299 0.2839109 0.5426306 0.5130068 0.7474814
#> sample_4 0.6494362 0.7169444 0.6591926 0.2529905 0.4458488 0.5446242 0.6100247
#> sample_5 0.4244373 0.8114162 0.5540032 0.5394045 0.5636868 0.3935201 0.6444605
#> sample_6 0.4148797 0.4725588 0.7899887 0.6970167 0.6493096 0.4148797 0.8847919
#> gene876 gene877 gene878 gene879 gene880 gene881 gene882
#> sample_1 0.5617003 0.4936924 0.6580266 0.5061692 0.5617003 0.6222547 0.4559574
#> sample_2 0.2101850 0.4075957 0.4819830 0.7758264 0.7697131 0.5547053 0.3244553
#> sample_3 0.6863999 0.5367299 0.5836052 0.8764715 0.3476236 0.6920059 0.5130068
#> sample_4 0.6347296 0.3922491 0.5344088 0.4774651 0.7359020 0.6930432 0.7169444
#> sample_5 0.5491468 0.4295517 0.4900922 0.6020359 0.2983112 0.7674231 0.5296225
#> sample_6 0.4265139 0.5733921 0.7127346 0.6385932 0.6116160 0.5290387 0.4611206
#> gene883 gene884 gene885 gene886 gene887 gene888 gene889
#> sample_1 0.4874351 0.5617003 0.5799914 0.4999371 0.3002399 0.7167425 0.3855582
#> sample_2 0.6065902 0.8001653 0.5807513 0.4144290 0.3870092 0.3244553 0.4075957
#> sample_3 0.6411598 0.3095632 0.3031712 0.5777868 0.3476236 0.7198755 0.4649740
#> sample_4 0.4352205 0.4983224 0.7074114 0.3922491 0.2758003 0.6737562 0.4983224
#> sample_5 0.4499016 0.3197966 0.5972755 0.7090026 0.3037006 0.7629792 0.5588499
#> sample_6 0.4896264 0.2027755 0.3914607 0.6599838 0.4725588 0.3440083 0.3796751
#> gene890 gene891 gene892 gene893 gene894 gene895 gene896
#> sample_1 0.5799914 0.5860645 0.4685870 0.3464726 0.2600545 0.4559574 0.5247905
#> sample_2 0.4685841 0.4416194 0.4212480 0.4144290 0.4551297 0.4075957 0.5936965
#> sample_3 0.7965233 0.7309492 0.3602009 0.7031857 0.5485195 0.3789658 0.3914090
#> sample_4 0.5900832 0.5190070 0.6591926 0.5950835 0.6248770 0.5190070 0.7264412
#> sample_5 0.6584374 0.6677105 0.5588499 0.4950691 0.4600123 0.6020359 0.4295517
#> sample_6 0.5009455 0.7127346 0.5065875 0.7696015 0.3017963 0.3499854 0.5234433
#> gene897 gene898 gene899 gene900 gene901 gene902 gene903
#> sample_1 0.3725845 0.3002399 0.6042125 0.7914444 0.6401924 0.2735077 0.2667884
#> sample_2 0.5019783 0.4953268 0.8122668 0.6258355 0.3524058 0.2749558 0.6449674
#> sample_3 0.5367299 0.5777868 0.4589139 0.4710215 0.6807831 0.3539191 0.7143228
#> sample_4 0.6347296 0.3704829 0.4774651 0.4458488 0.6149853 0.2125652 0.8825953
#> sample_5 0.8631677 0.4295517 0.5829377 0.7180832 0.3987006 0.5394045 0.5442806
#> sample_6 0.2341090 0.4031955 0.8552099 0.6653052 0.8798839 0.5122177 0.6759169
#> gene904 gene905 gene906 gene907 gene908 gene909 gene910
#> sample_1 0.8309338 0.8027786 0.4369159 0.5678094 0.3790781 0.3267431 0.4811652
#> sample_2 0.9133488 0.8423246 0.6513197 0.5416035 0.4007481 0.5086161 0.4685841
#> sample_3 0.7802674 0.5952073 0.4830791 0.5248924 0.6807831 0.5719568 0.3476236
#> sample_4 0.7593984 0.4511461 0.7826759 0.6591926 0.7264412 0.4245468 0.5292855
#> sample_5 0.6815534 0.3197966 0.5685140 0.5247166 0.4244373 0.4397482 0.4950691
#> sample_6 0.8994629 0.5678873 0.3678381 0.7644807 0.6493096 0.6116160 0.3678381
#> gene911 gene912 gene913 gene914 gene915 gene917 gene918
#> sample_1 0.5921256 0.4432761 0.5617003 0.6757587 0.7456878 0.3725845 0.2056490
#> sample_2 0.4212480 0.3662914 0.3103894 0.3103894 0.4752904 0.6828965 0.4416194
#> sample_3 0.7584511 0.3539191 0.2903452 0.4284233 0.6009911 0.6468533 0.5894120
#> sample_4 0.6737562 0.5190070 0.3485254 0.5446242 0.4191927 0.6248770 0.6100247
#> sample_5 0.6584374 0.5049923 0.5781394 0.6115284 0.5685140 0.3569407 0.4448302
#> sample_6 0.5457562 0.4952919 0.7075054 0.6599838 0.8502481 0.6278345 0.3737631
#> gene919 gene920 gene921 gene922 gene923 gene924 gene925
#> sample_1 0.7514445 0.2667884 0.3660771 0.4241562 0.4496233 0.5309728 0.4369159
#> sample_2 0.6322253 0.4075957 0.3384606 0.2101850 0.6639873 0.5416035 0.3103894
#> sample_3 0.4950870 0.6009911 0.4222868 0.3789658 0.6067634 0.4161373 0.6638675
#> sample_4 0.6396414 0.5395217 0.6640566 0.5547980 0.5395217 0.6050542 0.6930432
#> sample_5 0.3569407 0.6304019 0.4090283 0.3987006 0.4141756 0.2215644 0.6630784
#> sample_6 0.5898397 0.3259977 0.4265139 0.4725588 0.6546519 0.5568443 0.3855743
#> gene926 gene927 gene928 gene929 gene930 gene931 gene932
#> sample_1 0.5371428 0.3399101 0.3920247 0.5860645 0.5981750 0.2869027 0.5185959
#> sample_2 0.4752904 0.4348431 0.6130180 0.5612364 0.6065902 0.4819830 0.4483816
#> sample_3 0.6468533 0.4099748 0.4406578 0.5130068 0.7087596 0.6067634 0.3851940
#> sample_4 0.6248770 0.5497163 0.5395217 0.5850729 0.6199360 0.6100247 0.3430057
#> sample_5 0.4090283 0.4600123 0.6953171 0.1822532 0.6304019 0.5296225 0.6953171
#> sample_6 0.6439567 0.3737631 0.4496339 0.3855743 0.9430066 0.3017963 0.6170329
#> gene933 gene934 gene935 gene936 gene937 gene938 gene939
#> sample_1 0.5433004 0.4748825 0.3790781 0.4369159 0.4432761 0.6580266 0.6162523
#> sample_2 0.4348431 0.3454407 0.6449674 0.6449674 0.3662914 0.6065902 0.6130180
#> sample_3 0.5248924 0.4950870 0.6297394 0.3727242 0.5836052 0.5719568 0.6009911
#> sample_4 0.4245468 0.4617070 0.5138519 0.2587125 0.4722234 0.3595283 0.2758003
#> sample_5 0.4801073 0.4600123 0.3357858 0.2766322 0.3090779 0.4295517 0.7316402
#> sample_6 0.7899887 0.7387309 0.3139240 0.7335515 0.5122177 0.8001252 0.4090439
#> gene940 gene941 gene942 gene943 gene944 gene945 gene946
#> sample_1 0.7456878 0.5371428 0.4177565 0.7109208 0.5799914 0.3267431 0.3002399
#> sample_2 0.4212480 0.4348431 0.3524058 0.6386026 0.5152405 0.2463280 0.4483816
#> sample_3 0.5719568 0.6354552 0.3349919 0.6695169 0.6751555 0.6297394 0.6525358
#> sample_4 0.5750220 0.7733909 0.4511461 0.6640566 0.7593984 0.3263731 0.6737562
#> sample_5 0.7629792 0.5099385 0.3883284 0.5296225 0.5296225 0.5491468 0.4448302
#> sample_6 0.5346226 0.7439004 0.7696015 0.6332192 0.7899887 0.2957122 0.5843682
#> gene947 gene948 gene949 gene950 gene951 gene952 gene953
#> sample_1 0.5247905 0.6401924 0.1918968 0.4496233 0.6222547 0.5799914 0.5185959
#> sample_2 0.4212480 0.4752904 0.5218513 0.5677544 0.3524058 0.2820735 0.5019783
#> sample_3 0.8180579 0.7639205 0.5485195 0.4528412 0.6751555 0.0562509 0.4890892
#> sample_4 0.5035097 0.7121824 0.4826958 0.7359020 0.6347296 0.4983224 0.5395217
#> sample_5 0.7226107 0.9838228 0.6491285 0.6953171 0.3987006 0.1074978 0.3935201
#> sample_6 0.4553833 0.7231630 0.4839491 0.4090439 0.5953001 0.3914607 0.5065875
#> gene954 gene955 gene956 gene957 gene958 gene960 gene961
#> sample_1 0.5247905 0.4305426 0.5123888 0.6102383 0.5247905 0.3984778 0.5433004
#> sample_2 0.2962623 0.3662914 0.2246905 0.6954418 0.4416194 0.4007481 0.3593561
#> sample_3 0.5485195 0.6354552 0.3976107 0.3476236 0.4284233 0.3159412 0.5719568
#> sample_4 0.6785920 0.7640713 0.3976611 0.5190070 0.5750220 0.2067364 0.6882354
#> sample_5 0.5049923 0.4801073 0.5099385 0.4851049 0.4346554 0.1307478 0.4346554
#> sample_6 0.6385932 0.5513059 0.3199675 0.5346226 0.6116160 0.7335515 0.5513059
#> gene962 gene963 gene964 gene965 gene967 gene968 gene969
#> sample_1 0.3660771 0.2193403 0.5739064 0.7514445 0.3725845 0.2802124 0.5123888
#> sample_2 0.3732121 0.6065902 0.4685841 0.6322253 0.4551297 0.5416035 0.3662914
#> sample_3 0.1454071 0.5602617 0.6182740 0.5719568 0.7198755 0.7087596 0.6009911
#> sample_4 0.2984036 0.4191927 0.6640566 0.7593984 0.7169444 0.5800525 0.5344088
#> sample_5 0.4549623 0.3726857 0.6209836 0.6584374 0.4900922 0.6769479 0.2874961
#> sample_6 0.1582924 0.5401951 0.8601627 0.7075054 0.6007497 0.3619002 0.7542100
#> gene970 gene971 gene972 gene973 gene974 gene975 gene976
#> sample_1 0.2600545 0.7050881 0.6222547 0.4622786 0.3464726 0.1642078 0.5678094
#> sample_2 0.5284487 0.1515066 0.1883046 0.7451442 0.3033335 0.4551297 0.3938859
#> sample_3 0.4589139 0.2121818 0.6525358 0.6582071 0.4099748 0.3539191 0.7198755
#> sample_4 0.7169444 0.6882354 0.6199360 0.5344088 0.2241822 0.4722234 0.5138519
#> sample_5 0.5000358 0.6304019 0.6162607 0.5345185 0.4499016 0.3569407 0.7361422
#> sample_6 0.6385932 0.4553833 0.6278345 0.3855743 0.5733921 0.3559493 0.4265139
#> gene977 gene978 gene979 gene980 gene981 gene982 gene983
#> sample_1 0.59817498 0.4748825 0.4811652 0.5739064 0.6042125 0.5185959 0.6401924
#> sample_2 0.43484310 0.7203880 0.5677544 0.3174300 0.4819830 0.5284487 0.4075957
#> sample_3 0.42842332 0.7087596 0.7748286 0.7965233 0.3976107 0.5602617 0.5130068
#> sample_4 0.08107947 0.7264412 0.7593984 0.7121824 0.3704829 0.6100247 0.2984036
#> sample_5 0.50003581 0.8928500 0.8114162 0.6209836 0.3144432 0.2711817 0.6304019
#> sample_6 0.67591686 0.4380985 0.6759169 0.5733921 0.7644807 0.7022661 0.6116160
#> gene984 gene985 gene986 gene987 gene988 gene989 gene990
#> sample_1 0.6757587 0.2667884 0.6757587 0.2533059 0.4496233 0.6580266 0.6342247
#> sample_2 0.3938859 0.4416194 0.3870092 0.6130180 0.5936965 0.7758264 0.6194330
#> sample_3 0.6125244 0.4830791 0.4950870 0.4467559 0.2967653 0.5836052 0.5952073
#> sample_4 0.6050542 0.6248770 0.3922491 0.5241515 0.6978418 0.7311761 0.5035097
#> sample_5 0.5636868 0.4499016 0.3883284 0.4448302 0.2929097 0.7939153 0.5636868
#> sample_6 0.5346226 0.2773774 0.7231630 0.4207030 0.4725588 0.4090439 0.7439004
#> gene992 gene993 gene994 gene995 gene996 gene997 gene998
#> sample_1 0.5799914 0.5494459 0.7283531 0.6816468 0.5309728 0.5123888 0.5981750
#> sample_2 0.7327897 0.4551297 0.2749558 0.5742593 0.1217652 0.4752904 0.4212480
#> sample_3 0.5485195 0.2967653 0.6751555 0.5248924 0.5661151 0.3539191 0.5485195
#> sample_4 0.4879155 0.4191927 0.4511461 0.5190070 0.6298082 0.3813897 0.5138519
#> sample_5 0.5491468 0.4600123 0.6115284 0.3090779 0.4650518 0.6350972 0.5877265
#> sample_6 0.7490601 0.3559493 0.7644807 0.7644807 0.6706162 0.5953001 0.1130688
#> gene999 gene1000
#> sample_1 0.3984778 0.6698593
#> sample_2 0.3662914 0.4348431
#> sample_3 0.5485195 0.6582071
#> sample_4 0.6445436 0.5138519
#> sample_5 0.4900922 0.6209836
#> sample_6 0.4148797 0.6706162